Results 51 to 60 of about 3,604,842 (297)

Recent Advances in High‐Entropy Nanozymes: From Fabrication to Applications

Advanced Science, EarlyView.
To highlight key achievements and clarify the current landscape of high‐entropy nanozymes (HEAzymes), this review summarizes state‐of‐the‐art developments ranging from thermodynamically and kinetically controlled synthetic strategies; enzyme‐like catalytic types, catalytic characteristics, and underlying mechanisms; to their antioxidative, therapeutic,
Yongjian Ai, Weibo Zhang, Pengjie Wang, Wentao Xu, Huiyuan Guo, Hong‐bin Sun, Meng‐Qi He, Fazheng Ren, Qionglin Liang   +8 more
wiley   +1 more source

Association of asthma and anti-asthmatic therapy with oral health and microbiota alterations in children - a cross-sectional study

BMC Pediatrics
Background Asthma and its treatments are recognized as risk factors for oral health in children. The composition of oral microbiota is linked to asthma, as well as to the development of caries and other oral conditions.
Vojko Berce, Boris Egić, Anja Pintaric Lonzaric, Maja Rupnik, Aleksander Mahnic   +4 more
doaj   +1 more source

Does drug compliance change in asthmatic patients during pregnancy? [PDF]

, 2013
Background: Pregnant women with asthma are recommended to maintain optimal therapeutic management during pregnancy. Uncontrolled, symptomatic asthma may increase the risk of adverse peri-natal outcomes; thus adequate regular anti-asthmatic treatment must
ERKEKOL, Ferda Oner, Sevki Celen, Dilsad Mungan, Omur Aydin, Aydin, Omur, Celik, Gulfem, Insu Yilmaz, Yilmaz, Insu, Zeynep Misirligil, Mujdegul Karaca, CELEN, Sevki, Mungan, Dilsad, Ferda Erkekol, KARACA, Mujdegul Zayifoglu, Gulfem Celik, Misirligil, Zeynep, Karaca, MZ, Celik, G, Aydin, O, Erkekol, FERDA, Mungan, D, Misirligil, Z, Celen, S, Yilmaz, I   +23 more
core   +1 more source

Clinical Longitudinal Evaluation After Regimen Stop (CLEAR) of Dupilumab in Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Long‐term management strategies for severe chronic rhinosinusitis with nasal polyps (CRSwNP) increasingly include biologic therapy targeting Type 2 inflammation. However, data on outcomes after complete discontinuation of dupilumab following sustained disease control are scarce.
Patrick Huber, Manuel Lasch, Veronika Volgger, Clemens Stihl, Philipp Teupe, Fabienne Oettgen, Sophia Gantner, Moritz Gröger   +7 more
wiley   +1 more source

Cancer Chemoprevention and Piperine: Molecular Mechanisms and Therapeutic Opportunities

Frontiers in Cell and Developmental Biology, 2018
Cancer is a genetic disease characterized by unregulated growth and dissemination of malignantly transformed neoplastic cells. The process of cancer development goes through several stages of biochemical and genetic alterations in a target cell.
Rafiq A. Rather, Madhulika Bhagat
doaj   +1 more source

IN SILICO PHARMACOKINETIC, BIOACTIVITY AND TOXICITY STUDY OF SOME SELECTED ANTI-ASTHMATIC AGENTS

International Journal of Pharmaceutical Sciences and Drug Research, 2018
Asthma is a disease affecting the airways that carry air to and from lungs. Exposure to various irritants and substances that trigger allergies (allergens) can trigger signs and symptoms of asthma. The prevalence of asthma varies widely in different regions of the world due to distinct genetic, environmental and occupational risk factors.
Shashank Shekhar Mishra, Neeraj Kumar, Hamendra Pratap Singh, Shashi Ranjan, Chandra Shekhar Sharma   +4 more
openaire   +2 more sources

Biologics Adoption in CRSwNP and the Associated Decline in Endoscopic Sinus Surgery: A Longitudinal Claims Database Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Biologic treatments were introduced for chronic rhinosinusitis with nasal polyps (CRSwNP) in 2019. Treatment algorithms for medically refractory CRSwNP remain open, with patients choosing among surgery, biologics, or both. Real‐world utilization of surgery and biologics remains incompletely characterized.
Stephanie Shintani Smith, Sam L. Kaefer, Harsh Duvvuru, Robert C. Kern, Brent A. Senior, Vijay R. Ramakrishnan   +5 more
wiley   +1 more source

Anti-reflux therapy in asthmatic children

, 2011
Gastroesophageal reflux disease and asthma are the two diseases which are in a close relationship with each other. Occurance of one of these diseases causes a risk factor for the another. Anti-reflux treatment in asthmatic patients is a focus of interest
Uysal, Pinar, UZUNER, NEVİN
core   +1 more source

An Efficient Synthesis of the Anti-asthmatic Agent T-440: A Selective N-Alkylation of 2-Pyridone.

Chemical and Pharmaceutical Bulletin, 2000
6,7-Diethoxy-1-[1-(2-methoxyethyl)-2-oxo-1,2-dihydropyridin- 4-yl]naphthalene-2,3-dimethanol [T-440, (1)] is a potential anti-asthmatic agent based on selective phosphodiesterase 4 inhibition. It was necessary for the further evaluation of 1 to develop an efficient synthetic route for 1, especially the construction of the 1-(2-methoxyethyl)-2-pyridone ...
SUGAHARA, Masakatsu, MORITANI, Yasunori, KURODA, Tooru, KONDO, Kazuhiko, SHIMADZU, Hideshi, UKITA, Tatsuzo   +5 more
openaire   +3 more sources

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

British Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen, Patrick C. Souverein, Eibert R. Heerdink, Elisabeth Y. Bijlsma, Lucianne Groenink   +4 more
wiley   +1 more source