Results 41 to 50 of about 16,424 (267)

Local Specific IgE Levels Can Predict and Monitor the Therapeutic Response to Subcutaneous Immunotherapy With House Dust Mite

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Identifying predictive and monitoring biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This study aims to investigate the systemic and local levels of immunoglobulins and identify potential biomarkers in house dust mite (HDM) allergic rhinitis (AR) patients who are undergoing subcutaneous ...
Xu Xu, Jingyun Li, Xu Zhang, Yu Song, Lin Xi, Luo Zhang, Yuan Zhang   +6 more
wiley   +1 more source

Cancer Chemoprevention and Piperine: Molecular Mechanisms and Therapeutic Opportunities

Frontiers in Cell and Developmental Biology, 2018
Cancer is a genetic disease characterized by unregulated growth and dissemination of malignantly transformed neoplastic cells. The process of cancer development goes through several stages of biochemical and genetic alterations in a target cell.
Rafiq A. Rather, Madhulika Bhagat
doaj   +1 more source

IN SILICO PHARMACOKINETIC, BIOACTIVITY AND TOXICITY STUDY OF SOME SELECTED ANTI-ASTHMATIC AGENTS

International Journal of Pharmaceutical Sciences and Drug Research, 2018
Asthma is a disease affecting the airways that carry air to and from lungs. Exposure to various irritants and substances that trigger allergies (allergens) can trigger signs and symptoms of asthma. The prevalence of asthma varies widely in different regions of the world due to distinct genetic, environmental and occupational risk factors.
Shashank Shekhar Mishra, Neeraj Kumar, Hamendra Pratap Singh, Shashi Ranjan, Chandra Shekhar Sharma   +4 more
openaire   +2 more sources

Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion, Dioni‐Pinelopi Petsiou, Florian C. Fally, Karina Berbalk, Noah F. Melamed, Aldine Tu, Christina Morgenstern, Fana Alem Kidane, Mohammed Zghaebi, Linda Liu, Minghao Pan, Tina J. Bartosik, Victoria Stanek, Katarina Gangl, Julia Eckl‐Dorna, Sven Schneider   +15 more
wiley   +1 more source

Extent of Sinus Surgery Is Associated With Disease Control in Biologic Treated Type 2 Dominant CRS

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background A greater benefit of biologics is observed after surgery in Type 2 chronic rhinosinusitis with nasal polyps (CRSwNP). However, the extent of surgery remains undefined in many studies. This study evaluated the extent of surgery on disease control in patients receiving biologics for refractory Type 2 dominant CRSwNP.
Nicholas J. Campion, Peta‐Lee Sacks, Lu Hui Png, Ruoxin Hua, Rhea Darbari Kaul, Raquel Alvarado, Christine Choy, Raymond Sacks, Peter Earls, Raewyn G. Campbell, Larry Kalish, Richard J. Harvey   +11 more
wiley   +1 more source

Resveratrol as an anti-asthmatic agent: could this stilbenoid help against COVID-19 in any way? A meta-analysis

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, 2021
Resveratrol is a phenolic phytoconstituent found in many plants. This molecule has always caught the attention of scientists because of biological potentials such as inhibition of inflammation, oxidative stress and platelet aggregation as well as to prevent/protect against cardiovascular and neurodegenerative disease/disorders.
Ali Parlar, Amner Muñoz-Acevedo, Fatih Uckardes, Luisauris Jaimes, Ina Aneva, Bernardo Morales, Amina Unis, Maite Rodriguez, Onder Yumrutas, Raul Vinet, Simona Bungau, Jose L. Martinez   +11 more
openaire   +2 more sources

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Chronic Respiratory Disease Prevalence, Burden, and Treatment in Cape Town: A Cross‐Sectional Study

Health Science Reports
Background and Aims There is a high burden of respiratory symptoms in South Africa, but accurate classification of diagnoses is challenging. Due to the adverse risk profile, inhaled corticosteroid (ICS) treatment should only be used in specific ...
Marie Stolbrink, Lisanne Liebenberg, Tantaswa Ndlelana, Kischa Petersen, Stephanie Griffith‐Richards, Kevin Mortimer, Brian Allwood   +6 more
doaj   +1 more source

Leukotriene Receptor Antagonists in the Treatment of Asthma: Implications for Eosinophilic Inflammation

Canadian Respiratory Journal, 1999
Recent advances in the treatment and management of asthma have suggested that leukotriene (LT) receptor antagonists may be very beneficial as a second generation therapy with steroid-sparing properties and negligible side effects. These agents have shown
Redwan Moqbel
doaj   +1 more source

Which drugs are risk factors for the development of gastroesophageal reflux disease?

The Turkish Journal of Gastroenterology, 2017
Gastroesophageal reflux disease (GERD), which is common in many communities, is associated with structural factors, eating habits, and the use of certain drugs.
Zeynel Mungan, Binnur Pınarbaşı Şimşek   +1 more
doaj   +1 more source