Results 21 to 30 of about 3,604,842 (297)

Docking analysis and the possibility of prediction efficacy for an anti-IL-13 biopharmaceutical treatment with tralokinumab and lebrikizumab for bronchial asthma. [PDF]

PLoS ONE, 2017
Interleukin-13 (IL-13) is associated with allergic airway inflammation and airway remodeling. Our group found a variant with a single nucleotide polymorphism in the IL13 gene at position +2044G>A (rs20541) that was expected to result in the non ...
Yutaka Nakamura, Aki Sugano, Mika Ohta, Yutaka Takaoka   +3 more
doaj   +1 more source

Eficácia e segurança de dois inaladores de pó seco usados para a aplicação de furoato de mometasona em pacientes com asma Efficacy and safety of two dry-powder inhalers for the administration of mometasone furoate in asthma patients

Jornal Brasileiro de Pneumologia, 2010
OBJETIVO: O furoato de mometasona (FM) é um novo corticosteroide inalatório sintético potente. Internacionalmente, o FM é fornecido em um inalador de pó seco que permite sua administração em múltiplas doses.
Carlos Alberto de Castro Pereira, Flávia Fillardo Vianna, Alberto Cukier, Rafael Stelmach, Júlio César Abreu de Oliveira, Erich Vidal Carvalho, Edimar Pedrosa Gomes, Suzete Varela Mayo, Antônio Monteiro da Silva Chibante, Cláudia Patrícia Domingues   +9 more
doaj   +1 more source

Anti-asthmatic effect of fusarubin in an ovalbumin-induced asthmatic rat model [PDF]

, 2022
Purpose: To investigate the anti-asthmatic effect of fusarubin in an ovalbumin (OVA)-induced asthmatic rat model Methods: A rat model of asthma was employed in this investigation. Ovalbumin (OVA) was used to sensitise rats, and the rats were then treated
Yang, Dongyu, Kan, Junming, Hong, Jiajing, Wang, Fuchun   +3 more
core   +1 more source

Natural Products from Physalis alkekengi L. var. franchetii (Mast.) Makino: A Review on Their Structural Analysis, Quality Control, Pharmacology, and Pharmacokinetics

Molecules, 2022
The calyxes and fruits of Physalis alkekengi L. var. franchetii (Mast.) Makino (P. alkekengi), a medicinal and edible plant, are frequently used as heat-clearing and detoxifying agents in thousands of Chinese medicine prescriptions.
Jing Yang, Yanping Sun, Feng Cao, Bingyou Yang, Haixue Kuang   +4 more
doaj   +1 more source

Synthesis and in vitro evaluation of anti-inflammatory, antioxidant, and anti-fibrotic effects of new 8-aminopurine-2,6-dione-based phosphodiesterase inhibitors as promising anti-asthmatic agents [PDF]

, 2021
Phosphodiesterase (PDE) inhibitors are currently an extensively studied group of compounds that can bring many benefits in the treatment of various inflammatory and fibrotic diseases, including asthma.
Koczurkiewicz-Adamczyk, Paulina, Wyska, Elżbieta, Wójcik-Pszczoła, Katarzyna, Gosens, Reinoud, Plutecka, Hanna, Popiół, Justyna, Jankowska, Agnieszka, Chłoń-Rzepa, Grażyna, Świerczek, Artur, Pękala, Elżbieta, Pociecha, Krzysztof, Jakieła, Bogdan, Ślusarczyk, Marietta, Krzysztof Pociecha, Artur Świerczek, Reinoud Gosens, Bogdan Jakieła, Elżbieta Wyska, Paulina Koczurkiewicz-Adamczyk, Hanna Plutecka, Agnieszka Jankowska, Marietta Ślusarczyk, Elżbieta Pękala, Katarzyna Wójcik-Pszczoła, Justyna Popiół, Grażyna Chłoń-Rzepa   +25 more
core   +1 more source

Gas exchange during exercise in habitually active asthmatic subjects [PDF]

, 2005
We determined the relations among gas exchange, breathing mechanics, and airway inflammation during moderate- to maximum-intensity exercise in asthmatic subjects.
Haverkamp, HC, Eldridge, MW, Rodman, JR, Pegelow, DF, Miller, JD, Romer, LM, Dempsey, JA   +6 more
core   +1 more source

Severe eosinophilic asthma with IgG subclass deficiency treated with benralizumab and IVIG: a case report and literature review

Alergologia Polska
Severe asthma is characterized by poor symptom control and frequent recurrent exacerbations. Primary immunodeficiency with antibody deficiencies are the most common immunodeficiency phenotypes in adult patients and are characterized by frequent recurrent
Mehmet Cakmak, Nida Öztop
doaj   +1 more source

Development of bronchial sensitization to inhalant allergens in occupational asthma patients

Allergology International, 1997
In cases of occupational asthma due to reactive chemicals, an appreciable number of patients have persistent asthmatic symptoms and airway inflammation even after several years' avoidance of the cause agents. A case of late respiratory systemic syndrome (
Hae-sim Park, Dong-ho Nahm
doaj   +1 more source

Long-term efficacy of anti-IL-4 receptor antibody in a patient with aspirin-exacerbated respiratory disease and IgG4-related disease

Allergy, Asthma & Clinical Immunology, 2023
Background Aspirin-exacerbated respiratory disease (AERD) and IgG4-related disease (IgG4RD) share a common pathway of Th2-mediated immune mechanism; there have been several cases of IgG4RD developed in patients with asthma, especially in those comorbid ...
Hyun-Seob Jeon, Jae-Hyuk Jang, Youngsoo Lee, Hae-Sim Park   +3 more
doaj   +1 more source

Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation

Molecules, 2022
Oxidative stress is the key factor that strengthens free radical generation which stimulates lung inflammation. The aim was to explore antioxidant, bronchodilatory along with anti-asthmatic potential of folkloric plants and the aqueous methanolic crude ...
Taha Alqahtani, Sajida Parveen, Yahia Alghazwani, Hanan M. Alharbi, Reem M. Gahtani, Nadia Hussain, Kashif ur Rehman, Musaddique Hussain   +7 more
doaj   +1 more source