Results 11 to 20 of about 16,424 (267)

Serum IgE as a Biomarker of Severity and Short-term Treatment Response in Steroid-naïve Children with Asthma: A Hospital-based Prospective Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Paediatric asthma is a growing public health challenge in Low- and Middle-Income Countries (LMICs), with increasing prevalence and substantial morbidity.
Kishore Alagesan, Prasanna Raju, Vaishnavi Sivaji, Preethi Suresh, Padmanaban Srinivasan, Subash Sundar   +5 more
doaj   +1 more source

Parent’s perceptions and concerns about inhaled asthma therapy

Gazeta Médica, 2019
Aim: To determine parent´s perceptions and concerns about inhaled therapy and their relation to disease control. Methods:  A questionnaire was applied by interviewing parents of 119 asthmatic children attending the Pediatric Allergy or Pneumology ...
Rita Barreira, Madalena Sales Luís, Sara Marcos, Vivian Gonçalves, Rita Monteiro, Maria João Leiria   +5 more
doaj   +1 more source

Docking analysis and the possibility of prediction efficacy for an anti-IL-13 biopharmaceutical treatment with tralokinumab and lebrikizumab for bronchial asthma. [PDF]

PLoS ONE, 2017
Interleukin-13 (IL-13) is associated with allergic airway inflammation and airway remodeling. Our group found a variant with a single nucleotide polymorphism in the IL13 gene at position +2044G>A (rs20541) that was expected to result in the non ...
Yutaka Nakamura, Aki Sugano, Mika Ohta, Yutaka Takaoka   +3 more
doaj   +1 more source

Eficácia e segurança de dois inaladores de pó seco usados para a aplicação de furoato de mometasona em pacientes com asma Efficacy and safety of two dry-powder inhalers for the administration of mometasone furoate in asthma patients

Jornal Brasileiro de Pneumologia, 2010
OBJETIVO: O furoato de mometasona (FM) é um novo corticosteroide inalatório sintético potente. Internacionalmente, o FM é fornecido em um inalador de pó seco que permite sua administração em múltiplas doses.
Carlos Alberto de Castro Pereira, Flávia Fillardo Vianna, Alberto Cukier, Rafael Stelmach, Júlio César Abreu de Oliveira, Erich Vidal Carvalho, Edimar Pedrosa Gomes, Suzete Varela Mayo, Antônio Monteiro da Silva Chibante, Cláudia Patrícia Domingues   +9 more
doaj   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Natural Products from Physalis alkekengi L. var. franchetii (Mast.) Makino: A Review on Their Structural Analysis, Quality Control, Pharmacology, and Pharmacokinetics

Molecules, 2022
The calyxes and fruits of Physalis alkekengi L. var. franchetii (Mast.) Makino (P. alkekengi), a medicinal and edible plant, are frequently used as heat-clearing and detoxifying agents in thousands of Chinese medicine prescriptions.
Jing Yang, Yanping Sun, Feng Cao, Bingyou Yang, Haixue Kuang   +4 more
doaj   +1 more source

Nonsteroidal Anti-Inflammatory Agents in the Treatment of Asthma in Children

Canadian Respiratory Journal, 1995
The increasing scientific information clearly demonstrates the important role of inflammation in asthma. This evidence has led physicians to focus their treatment on the elimination of inflammation instead of working solely against bronchoconstriction ...
Pierre Gaudreault
doaj   +1 more source

Development of bronchial sensitization to inhalant allergens in occupational asthma patients

Allergology International, 1997
In cases of occupational asthma due to reactive chemicals, an appreciable number of patients have persistent asthmatic symptoms and airway inflammation even after several years' avoidance of the cause agents. A case of late respiratory systemic syndrome (
Hae-sim Park, Dong-ho Nahm
doaj   +1 more source

Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation

Molecules, 2022
Oxidative stress is the key factor that strengthens free radical generation which stimulates lung inflammation. The aim was to explore antioxidant, bronchodilatory along with anti-asthmatic potential of folkloric plants and the aqueous methanolic crude ...
Taha Alqahtani, Sajida Parveen, Yahia Alghazwani, Hanan M. Alharbi, Reem M. Gahtani, Nadia Hussain, Kashif ur Rehman, Musaddique Hussain   +7 more
doaj   +1 more source

Long-term efficacy of anti-IL-4 receptor antibody in a patient with aspirin-exacerbated respiratory disease and IgG4-related disease

Allergy, Asthma & Clinical Immunology, 2023
Background Aspirin-exacerbated respiratory disease (AERD) and IgG4-related disease (IgG4RD) share a common pathway of Th2-mediated immune mechanism; there have been several cases of IgG4RD developed in patients with asthma, especially in those comorbid ...
Hyun-Seob Jeon, Jae-Hyuk Jang, Youngsoo Lee, Hae-Sim Park   +3 more
doaj   +1 more source