Results 61 to 70 of about 32,098 (325)

Relationship Between Different Types and Forms of Anti-Asthmatic Medications and Dental Caries in Three to 12 Year Olds

open access: yesFrontiers in Dentistry, 2016
Objectives: Asthma is a common chronic disease. Asthma and anti-asthmatic medications have been suggested as risk factors for increased susceptibility to caries.
Alireza Heidari   +5 more
doaj  

Cancer Chemoprevention and Piperine: Molecular Mechanisms and Therapeutic Opportunities

open access: yesFrontiers in Cell and Developmental Biology, 2018
Cancer is a genetic disease characterized by unregulated growth and dissemination of malignantly transformed neoplastic cells. The process of cancer development goes through several stages of biochemical and genetic alterations in a target cell.
Rafiq A. Rather, Madhulika Bhagat
doaj   +1 more source

Ruxolitinib Ameliorates Airway Hyperresponsiveness and Lung Inflammation in a Corticosteroid-Resistant Murine Model of Severe Asthma

open access: yesFrontiers in Immunology, 2021
Asthma prevalence has increased considerably over the decades and it is now considered as one of the most common chronic disorders in the world. While the current anti-asthmatic therapies are effective for most asthma patients, there are 5-10% subjects ...
Hariharan Subramanian   +5 more
doaj   +1 more source

Integrating evidence for managing asthma in patients who smoke [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Bjermer, Leif   +3 more
core   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

open access: yesAdvanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou   +3 more
wiley   +1 more source

気管支喘息における気管支肺胞洗浄液中の細胞成分に対する加齢および副腎皮質ホルモンの影響 [PDF]

open access: yes, 2002
Effects of aging and glucocorticoid therapy on bronchoalveolar lavage (BAL) cells, particularly lymphocytes, neutrophils and eosinophils, were examined in 81 patients with asthma. 1.
Ashida, Kozo   +8 more
core   +1 more source

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

open access: yesAdvanced Science, EarlyView.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu   +17 more
wiley   +1 more source

Asthma and Therapeutics: Recombinant Therapies in Asthma

open access: yesAllergy, Asthma & Clinical Immunology, 2005
Numerous recombinant therapies are being investigated for the treatment of asthma. This report reviews the current status of several of these novel agents.
Cockcroft Donald W
doaj   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

open access: yesAdvanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu   +5 more
wiley   +1 more source

The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications

open access: yesAngewandte Chemie, EarlyView.
The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet   +7 more
wiley   +2 more sources

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