Results 71 to 80 of about 59,985 (224)
Association of SIRT6 Expression With Risk of Pneumonitis Induced by Radiotherapy in Cancer Patients
Molecular Carcinogenesis, EarlyView.ABSTRACT Thoracic tumours represent a significant proportion of malignant cancers. While radiotherapy (RT) improves prognosis, it can also lead to side effects such as radiation‐induced pneumonitis (RP). Since SIRT6 is involved in DNA repair, energy metabolism and inflammation, this study aims to investigate the expression of SIRT6 in lymphocytes as a ...
Fengyuan Yu +14 more
wiley +1 more source
Regimes and Mechanisms of Inflammation Described by a Reaction–Diffusion System
Mathematical Methods in the Applied Sciences, EarlyView.ABSTRACT Inflammation is a biological response of the immune system to external stimuli such as injury or infection. It plays an important role in various diseases including atherosclerosis, cancer, and neurodegenerative diseases. This work presents a generic inflammation model based on reaction–diffusion equations that describes the concentrations of ...
W. El Hajj, N. El Khatib, V. Volpert
wiley +1 more source
Clinical Transplantation, Volume 36, Issue 11, November 2022., 2022 Abstract Background We reviewed the scientific literature to gain insight on the epidemiology and outcome of Strongyloides stercoralis infections after transplantation. Methods CINAHL, PUBMED, and OVID/MEDLINE were reviewed from inception through March 31, 2022 using key words Strongyloides and transplantation.
Cybele Lara R. Abad +3 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Fanastomig (also known as EMB‐02) is a bispecific antibody targeting programmed cell death protein‐1(PD‐1) and lymphocyte activation gene‐3 (LAG‐3), developed for the treatment of advanced solid tumors. A first‐in‐human (FIH) Phase I study (NCT04618393) evaluated safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD ...
Chengjun Jiang +6 more
wiley +1 more source
European Journal of Clinical Investigation, Volume 53, Issue 1, January 2023., 2023 Graphical abstract MP3‐pulses‐COVID‐19 trial. Abstract Background The efficacy and safety of high versus medium doses of glucocorticoids for the treatment of patients with COVID‐19 has shown mixed outcomes in controlled trials and observational studies.
Luis Corral‐Gudino +21 more
wiley +1 more source
arXivThanks to advances in large language models, a new type of software agent, the artificial intelligence (AI) agent, has entered the marketplace. Companies such as OpenAI, Google, Microsoft, and Salesforce promise their AI Agents will go from generating passive text to executing tasks.
arxiv
The Potency of Monoterpenes Contained in Essential Oils of Canary Sap (Canarium indicum L.) as Anti-inflammatory Agent on Asthmatic Rats (Rattus norvegicus) [PDF]
, 2018 Velayaty Labone Azzahra +2 more
openalex +1 more source
SAGA: A Security Architecture for Governing AI Agentic Systems [PDF]
arXivLarge Language Model (LLM)-based agents increasingly interact, collaborate, and delegate tasks to one another autonomously with minimal human interaction. Industry guidelines for agentic system governance emphasize the need for users to maintain comprehensive control over their agents, mitigating potential damage from malicious agents. Several proposed
arxiv
Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development
Small, EarlyView.Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen +7 more
wiley +1 more source