Results 31 to 40 of about 356,287 (308)

Phlegmonous gastritis: Evolving from surgical to medical disease

IDCases, 2023
We present a case of phlegmonous gastritis, which is a rare, life-threatening infection involving transmural inflammation of the stomach of multiple possible etiologies.
Michael T. Czapka, Stephen J. Schrantz
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Evaluation of different detection methods of biofilm formation in the clinical isolates

Brazilian Journal of Infectious Diseases
BACKGROUND: Microorganisms growing in a biofilm are associated with chronic and recurrent human infections and are highly resistant to antimicrobial agents.
Afreenish Hassan, Javaid Usman, Fatima Kaleem, Maria Omair, Ali Khalid, Muhammad Iqbal   +5 more
doaj   +1 more source

Physicochemical Characteristics of Nanoliposome Garlic (Allium sativum L.) Essential Oil and Its Antibacterial Effect on Escherichia coli O157:H7 [PDF]

Journal of Food Quality and Hazards Control, 2017
Background: Escherichia coli O157:H7 is a Gram-negative and facultative anaerobic food-borne bacterial pathogen. The major purpose of this study was to evaluate physicochemical characteristics of nanoliposome garlic Essential Oil (EO) and its ...
A. Zabihi, A. Akhondzadeh Basti, G. Amoabediny, A. Khanjari, J. Tavakkoly Bazzaz, F. Mohammadkhan, A. Hajjar Bargh, E. Vanaki   +7 more
doaj  

Initial respiratory specimen bacteriology and isolates susceptibility to antimicrobials in promptly intubated chronic obstructive pulmonary disease adults - single-center two-year experience [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2019
Introduction/Objective. Chronic obstructive pulmonary disease (COPD) exacerbation is mostly triggered by infectious agents and seriously compromises the patient’s quality of life and predicts a poor outcome of the disease as well.
Gluvić Zoran, Mitrović Bojan, Radojević Biljana, Krasnjuk Andrej, Panić Miloš, Miličević Predrag, Vukčević Miodrag, Tomašević Ratko, Putniković Biljana, Nešković Aleksandar N.   +9 more
doaj   +1 more source

Synthesis and evaluation of novel benzimidazole derivatives as potential anti bacterial and anti fungal agents [PDF]

, 2021
Vishwajeet Amarsingh Pardeshi, Sultan Pathan, Amit Bhargava, Narendra Singh Chundawat, Girdhar Pal Singh   +4 more
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Effect of K1, K2 Anti-Bacterial Agents on Tobacco Ralstonia Solanacearum

Engineering, 2010
The tobacco Ralstonia Solanacearum were both cultured on nutrient agar plates and inoculated in seedling stage of tobacco, then treated with K1 and K2, two anti-bacterial agents, at a serial con-centrations to study their inhibitory efficiency. The result indicated that K1 can inhibit R.
Anan Wang, Zhifeng Zhao, Zhenzhen Liu, Yixin Liu   +3 more
openaire   +3 more sources