Results 151 to 160 of about 153,642 (269)
Introduction: Biofilms are communities of microorganisms embedded in a self-produced extracellular polymeric matrix. Bacterial cells are protected from antimicrobial agents in biofilm structure.
Zianab Mohsenipour, Mehdi Hassanshahian
doaj
Intelligent design of artificial biocatalyst for biomedical diseases
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang +3 more
wiley +1 more source
Diagnostic modulation of subgingival proteomic biomarkers by age and smoking habits in periodontitis
Abstract Background Although age and smoking influence the periodontal proteome, their impact on subgingival biomarkers for diagnosing periodontitis remains unclear. This multicenter study assessed their influence on subgingival proteins for disease detection.
Triana Blanco‐Pintos +8 more
wiley +1 more source
Abstract Background The aim of this study is to determine whether the timing of metronidazole (MTZ) and amoxicillin (AMX) administration, relative to scaling and root planing (SRP), influences the clinical and microbiological outcomes of periodontal treatment.
Daiane Fermiano +10 more
wiley +1 more source
Abstract Background The biofilm‐inhibitory effects of electrolyzed saline (EOS) vary widely due to differences in formulations and treatment methods. This study analyzed the impact of EOS on key oral microbial species and used serial 3D‐intraoral scans to evaluate its effects on de novo biofilm formation.
Katja Povšič +6 more
wiley +1 more source
Synthesis and antibacterial activity study of anti-biofilm agents based on American oyster defensin analog A4. [PDF]
Zhang X, Liu Y, Geng Z, Guo Y.
europepmc +1 more source
Abstract Background Immunomodulatory agents such as omega‐3 (ω‐3) and low‐dose aspirin (ASA) have been proposed as effective adjuncts in the treatment of periodontitis. However, they still lack long‐term studies and head‐to‐head evaluation with metronidazole (MTZ) and amoxicillin (AMX), the adjunct protocol with the strongest scientific evidence of ...
Nidia C. Castro dos Santos +14 more
wiley +1 more source
New Anti-Telomerase Anti-Cancer Agents
The unlimited proliferative potential of cancer cells depends on telomere maintenance. Optimal telomerase activity requires in chromosomal DNA an unfolded single-stranded telomeric overhang.
PETRACCONE, LUIGI
core
Abstract Background Periodontitis is a widespread, chronic infection‐triggered inflammatory condition in which professional supportive periodontal care (SPC) and daily oral hygiene form the backbone to reduce the disease activity. Light‐based treatments have shown promising antibacterial effects, but their potential for routine home use has not been ...
Paula Tegelberg +9 more
wiley +1 more source
Abstract Background Periodontal disease (PD) is associated with type 2 diabetes mellitus (T2DM), while periodontal treatment (PT) improves glycemic control in T2DM patients. Leptin and adiponectin belong to the adipokines family and have almost antagonistic functions in inflammatory processes and insulin sensitivity modulation.
Natalia Christaki +3 more
wiley +1 more source

