Results 161 to 170 of about 3,661,773 (260)

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Structural Insights into Curli CsgA Cross-β Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents. [PDF]

PLoS Pathog, 2019
Perov S, Lidor O, Salinas N, Golan N, Tayeb-Fligelman E, Deshmukh M, Willbold D, Landau M.   +7 more
europepmc   +1 more source

Diverse Uses of Lantibiotics: Exploring New Approaches to Combat Antibiotic Resistance

Medicine Advances, EarlyView.
This review illustrates lantibiotics as an alternative therapeutic approach to combat antibiotic resistance, highlighting their diverse sources, including plants, insects, animals, and microorganisms. It further emphasizes their broad therapeutic potential, including antibacterial, antifungal, antiparasitic, antiviral, and anticancer activities (GA ...
Gopalarethinam Janani, Shangavy Pandiarajan, Kunal Biswas, Manickam Rajkumar, Agnishwar Girigoswami, Koyeli Girigoswami   +5 more
wiley   +1 more source

Enhanced Recovery After Surgery in Simultaneous Pancreas–Kidney Transplantation: A Retrospective Cohort Analysis of Perioperative Outcomes

Organ Medicine, EarlyView.
ABSTRACT Background While simultaneous pancreas–kidney transplantation (SPK) is an established therapeutic intervention for patients with end‐stage renal disease and diabetes, it has been associated with prolonged recovery periods and high complication rates.
Rongxin Chen, Luhao Liu, Jialin Wu, Zhuangqiang Fang, Guanghui Li, Zheng Chen   +5 more
wiley   +1 more source

Discovery of edodine, a natural compound from Lentinula edodes with antibacterial activity for the biological control of fire blight pathogen Erwinia amylovora

Pest Management Science, EarlyView.
Novel edodine was identified from Lentinula edodes HK761, exhibiting biocontrol potential against fire blight by affecting motility, intracellular ATP level, and cell division of Erwinia amylovora. Abstract BACKGROUND In the search for biological resources with antibacterial activity against Erwinia amylovora, the culture filtrate of Lentinula edodes ...
Yeong Seok Kim, Jae Woo Han, Bomin Kim, Chunggeon Lee, Daeui Park, Jaehyuk Choi, Gyung Ja Choi, Hun Kim   +7 more
wiley   +1 more source

Bioactivity profiling of linear venom peptides from Italian small wood‐scorpion (Euscorpius italicus)

Pest Management Science, EarlyView.
Functional screening pipeline of venom peptides from Euscorpius italicus reveal their activity towards globally important pest insects, bacteria, and cells – providing insight on the potential and function of arachnid venom peptides. Abstract BACKGROUND Rising host‐expansion and the global spread of pest insects, confront agricultural sectors with ...
Maurice Pierry, Ludwig Dersch, Jonas Krämer, Lennart Schulte, Ignazio Avella, Tobias Kessel, Kornelia Hardes, Michael Marner, Jens Grotmann, Maximilian Seip, Till F. Schäberle, Tim Lüddecke   +11 more
wiley   +1 more source

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Multi‐Scale Magnetically Controlled Soft Matter Robots for Tissue Interfacing Applications

SmartBot, EarlyView.
Magnetically controlled soft matter robots (MSMRs) integrate remote magnetic control with soft matter adaptability for minimally invasive biomedical tasks at tissue interfaces across multiple scales. This review examines the interaction mechanisms between MSMRs and tissue interfaces, with MSMRs classified into five categories according to their ...
Wenxin Lian, Yan Zhou, Dianhong Zhang, Yuanwen Liang, Zihao Tang, Zhuo Chen, Qichen Hong, Jiangfan Yu, Chi Zhang, Xiaopu Wang   +9 more
wiley   +1 more source

Binder Design in Extrusion‐Based 3D Printing of Electrodes: Enhancing Printability and Electrochemical Performance in Energy Storage Devices

Small, EarlyView.
Binder design plays a pivotal role in extrusion‐based 3D printing of energy storage electrodes by simultaneously governing ink printability and electrochemical performance. This review examines how diverse binder materials and design strategies are employed to enable printability while addressing key electrochemical challenges in energy storage devices,
Akesh Manimendra Badalge, Timothy J. Biddle, Huynh Tam Minh Nguyen, Eric Campbell, Munkhbayar Batmunkh, Tak Kim, Stefanie Feih, Yu Lin Zhong   +7 more
wiley   +1 more source

Mechanism‐Guided Engineering of Upconversion Nanoparticles for Antibacterial Phototherapy: From Photonic Principles to Translational Nanosystems

Small, EarlyView.
This review provides a systematic overview of the field of antibacterial PhotoDynamic Therapy (aPDT) triggered by upconversion nanoparticles (UCNPs), focusing on the mechanisms and the key factors that define their efficacy for generating bactericidal species upon NIR‐light activation.
Zhe Li, Calum Johnston, Barbara Lonetti, Clément Roux   +3 more
wiley   +1 more source