Results 21 to 30 of about 153,642 (269)

Anti-biofilm activity as a health issue

Frontiers in Microbiology, 2016
The formation and persistence of surface-attached microbial communities, known as biofilms, are responsible for 75% of human microbial infections (National Institutes of Health).
Sylvie eMiquel, Rosyne eLagrafeuille, Bertrand eSouweine, Bertrand eSouweine, Christiane eForestier   +4 more
doaj   +2 more sources

Novel Chronic Wound Healing by Anti-biofilm Peptides and Protease [PDF]

Advanced Pharmaceutical Bulletin, 2022
Chronic wounds have made a challenge in medical healthcare due to their biofilm infections,which reduce the penetrance of the antibacterial agents in the injury site.
Fatemeh Sadat Ghoreishi, Rasoul Roghanian, Giti Emtiazi   +2 more
doaj   +1 more source

Synthesis and Evaluation of Ciprofloxacin-Nitroxide Conjugates as Anti-Biofilm Agents. [PDF]

Molecules, 2016
As bacterial biofilms are often refractory to conventional antimicrobials, the need for alternative and/or novel strategies for the treatment of biofilm related infections has become of paramount importance. Herein, we report the synthesis of novel hybrid molecules comprised of two different hindered nitroxides linked to the piperazinyl secondary amine
Verderosa AD, Mansour SC, de la Fuente-Núñez C, Hancock RE, Fairfull-Smith KE.   +4 more
europepmc   +9 more sources

Anti-biofilm agents from marine biota

Journal of Chemical Technology and Metallurgy, 2023
Microbial biofilm forms on any living or non-living material surface contacting with microbial species. It is a persistent world-weight spread problem with very high prize. This explains the exclusive interest to development of anti-biofilm material surfaces.
Vladkova T.G., Martinov B.L., Gospodinova D.N.   +2 more
openaire   +2 more sources

Microemulsions are highly effective anti-biofilm agents [PDF]

Letters in Applied Microbiology, 2003
The demonstration of the antibiofilm effects of pharmaceutical microemulsions.Microemulsions were prepared as physically stable oil/water systems. Previous work by this group has shown that microemulsions are highly effective antimembrane agents that result in rapid losses of viability in planktonic populations of Pseudomonas aeruginosa and ...
I S I, Al-Adham, N D, Al-Hmoud, E, Khalil, M, Kierans, P J, Collier   +4 more
openaire   +2 more sources

An Overview of Biofilm Formation–Combating Strategies and Mechanisms of Action of Antibiofilm Agents

Life, 2022
Biofilm formation on surfaces via microbial colonization causes infections and has become a major health issue globally. The biofilm lifestyle provides resistance to environmental stresses and antimicrobial therapies.
Syeda Tasmia Asma, Kálmán Imre, Adriana Morar, Viorel Herman, Ulas Acaroz, Hamid Mukhtar, Damla Arslan-Acaroz, Syed Rizwan Ali Shah, Robin Gerlach   +8 more
doaj   +1 more source

Coumarin derivatives as new anti-biofilm agents against Staphylococcus aureus. [PDF]

PLoS One
Staphylococcus aureus infections are the primary causes of morbidity, and mortality, particularly in immuno-compromised individuals. S. aureus associated infections are acquired from community, as well as hospital settings, and difficult to treat because of the emerging resistance against available antibiotics.
Wahab AT, Nadeem F, Salar U, Bilal HM, Farooqui M, Javaid S, Sadaf S, Khan KM, Choudhary MI.   +8 more
europepmc   +3 more sources

Combination Therapies for Biofilm Inhibition and Eradication: A Comparative Review of Laboratory and Preclinical Studies

Frontiers in Cellular and Infection Microbiology, 2022
Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are currently being developed as treatments for biofilm infections ...
Sophia Hawas, Sophia Hawas, Anthony D. Verderosa, Anthony D. Verderosa, Makrina Totsika, Makrina Totsika   +5 more
doaj   +1 more source

The Potential of Human Peptide LL-37 as an Antimicrobial and Anti-Biofilm Agent [PDF]

Antibiotics, 2021
The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat bacterial infections. The development of novel therapeutic agents is crucial in avoiding a post-antibiotic era and the associated deaths from antibiotic resistant pathogens. The human antimicrobial peptide LL-37 has been considered as a potential alternative to
Kylen E. Ridyard, Joerg Overhage
openaire   +3 more sources

Activity of Phage–Lactoferrin Mixture against Multi Drug Resistant Staphylococcus aureus Biofilms

Antibiotics, 2022
Biofilms are complex bacterial structures composed of bacterial cells embedded in extracellular polymeric substances (EPS) consisting of polysaccharides, proteins and lipids. As a result, biofilms are difficult to eradicate using both mechanical methods,
Katarzyna Kosznik-Kwaśnicka, Natalia Kaźmierczak, Lidia Piechowicz   +2 more
doaj   +1 more source