Results 31 to 40 of about 3,661,773 (260)

An Overview of Biofilm Formation–Combating Strategies and Mechanisms of Action of Antibiofilm Agents

Life, 2022
Biofilm formation on surfaces via microbial colonization causes infections and has become a major health issue globally. The biofilm lifestyle provides resistance to environmental stresses and antimicrobial therapies.
Syeda Tasmia Asma, Kálmán Imre, Adriana Morar, Viorel Herman, Ulas Acaroz, Hamid Mukhtar, Damla Arslan-Acaroz, Syed Rizwan Ali Shah, Robin Gerlach   +8 more
doaj   +1 more source

Combination Therapies for Biofilm Inhibition and Eradication: A Comparative Review of Laboratory and Preclinical Studies

Frontiers in Cellular and Infection Microbiology, 2022
Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are currently being developed as treatments for biofilm infections ...
Sophia Hawas, Sophia Hawas, Anthony D. Verderosa, Anthony D. Verderosa, Makrina Totsika, Makrina Totsika   +5 more
doaj   +1 more source

Activity of Phage–Lactoferrin Mixture against Multi Drug Resistant Staphylococcus aureus Biofilms

Antibiotics, 2022
Biofilms are complex bacterial structures composed of bacterial cells embedded in extracellular polymeric substances (EPS) consisting of polysaccharides, proteins and lipids. As a result, biofilms are difficult to eradicate using both mechanical methods,
Katarzyna Kosznik-Kwaśnicka, Natalia Kaźmierczak, Lidia Piechowicz   +2 more
doaj   +1 more source

Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors. [PDF]

J Med Chem, 2019
International audienceBiofilm formation is a key mechanism of antimicrobial resistance. We have recently reported two classes of orally bioavailable C-glycosidic inhibitors of the Pseudomonas aeruginosa lectin LecB with anti-biofilm activity. They proved
Sommer R, Rox K, Wagner S, Hauck D, Henrikus SS, Newsad S, Arnold T, Ryckmans T, Brönstrup M, Imberty A, Varrot A, Hartmann RW, Titz A.   +12 more
europepmc   +2 more sources

N-benzylimidazoles as potential antimicrobial and antibiofilm agents – syntheses, bioactivity and molecular docking studies

Scientific African, 2023
Biofilm formation has been identified as one of the major pathways by which pathogens evade the effect of antimicrobial agents, leading to drug resistance in general. The imidazole ring provides a promising scaffold for the design of viable antimicrobial
Caleb Impraim Aboagye, Gilbert Boadu Ampomah, Jehoshaphat Oppong Mensah, Caleb Nketia Mensah, Daniel Nartey, Edward Ntim Gasu, Lawrence Sheringham Borquaye   +6 more
doaj   +1 more source

Coumarin derivatives as new anti-biofilm agents against Staphylococcus aureus. [PDF]

PLoS One
Staphylococcus aureus infections are the primary causes of morbidity, and mortality, particularly in immuno-compromised individuals. S. aureus associated infections are acquired from community, as well as hospital settings, and difficult to treat because of the emerging resistance against available antibiotics.
Wahab AT, Nadeem F, Salar U, Bilal HM, Farooqui M, Javaid S, Sadaf S, Khan KM, Choudhary MI.   +8 more
europepmc   +3 more sources

Biofilm Formation, and Related Impacts on Healthcare, Food Processing and Packaging, Industrial Manufacturing, Marine Industries, and Sanitation–A Review

Applied Microbiology, 2023
Biofilm formation can lead to problems in healthcare, water distribution systems, food processing and packaging, industrial manufacturing, marine industries, and sanitation.
Ghazal Shineh, Mohammadmahdi Mobaraki, Mohammad Jabed Perves Bappy, David K. Mills   +3 more
doaj   +1 more source

Importance of SigB for Listeria monocytogenes static and continuous flow biofilm formation and disinfectant resistance [PDF]

, 2010
Listeria monocytogenes is a food-borne pathogen that is able to form biofilms in food processing facilities. Biofilms are generally more resistant to antimicrobial agents, making it difficult to eradicate them during cleanup procedures. So far, little is
Veen, S., van der, Abee, T., Tjakko Abee, Stijn van der Veen   +3 more
core   +1 more source

How well are we translating biofilm research from bench-side to bedside?

Biofilm, 2020
Biofilms are responsible for more than 80% of all chronic infections and represent an enormous medical challenge. In order to meet this challenge, translation research on anti-biofilm approaches is desperately needed.
Kendra P. Rumbaugh
doaj   +1 more source

Image_1_Promising Anti-Biofilm Agents and Phagocytes Enhancers for the Treatment of Candida albicans Biofilm–Associated Infections.jpeg

, 2022
Little is known about the interactions among phagocytes and antifungal agents and the antifungal immunomodulatory activities on Candida species biofilms. Here, inhibition of C. albicans biofilms and the interactions among biofilms and phagocytes alone or
Gamal A. Elmowalid (12984488), Yasmine H. Tartor (11744636), Mohamed N. Hassan (12984491), Taisir Saber (12057086), Dalia F. Ashour (12984494), Asmaa Shaker (10511848)   +5 more
core   +1 more source