Results 171 to 180 of about 10,355 (194)
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Clinical Rheumatology, 2019
Detection of autoantibodies in sera of rheumatoid arthritis (RA) patients has an important role in diagnosis and management strategies. Recently, another type of autoantibodies has been detected with activity against carbamylated proteins (anti-CarP) which may play an important role in the diagnosis of RA.
Sahar A. Elsayed +3 more
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Detection of autoantibodies in sera of rheumatoid arthritis (RA) patients has an important role in diagnosis and management strategies. Recently, another type of autoantibodies has been detected with activity against carbamylated proteins (anti-CarP) which may play an important role in the diagnosis of RA.
Sahar A. Elsayed +3 more
openaire +2 more sources
Arg‐gingipain, myeloperoxidase, and anti‐CarP across the rheumatoid arthritis spectrum
Journal of PeriodontologyAbstractBackgroundThe association between periodontitis (PD) and rheumatoid arthritis (RA) has been linked to autoantibodies. In recent years, Arg‐gingipain (Rgp) triggered myeloperoxidase (MPO) release, which mediates protein carbamylation to form anti‐carbamylated proteins (anti‐CarP), perpetuating RA progression has gained interest.
Maliha Shahbaz +6 more
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Medicina Clínica (English Edition)
OBJECTIVE: To analyze the association of anti-CarP levels with clinical activity, manifestations, and serological profile in rheumatoid arthritis (RA) patients. METHODS: Cross-sectional study including RA patients and healthy controls (HC). Clinical and analytical data were collected, and anti-CarP levels were measured by ELISA. RESULTS: A total of 101
Martínez Calabuig P +2 more
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OBJECTIVE: To analyze the association of anti-CarP levels with clinical activity, manifestations, and serological profile in rheumatoid arthritis (RA) patients. METHODS: Cross-sectional study including RA patients and healthy controls (HC). Clinical and analytical data were collected, and anti-CarP levels were measured by ELISA. RESULTS: A total of 101
Martínez Calabuig P +2 more
openaire +2 more sources
Annals of the Rheumatic Diseases, 2019
Background: (SLE) is a chronic autoimmune disease with a complex pathogenesis in which genes and environmental factors interact leading to a protean clinical picture. Joint involvement is one of the most common manifestations in SLE patients, with a prevalence ranging from 69 to 95%. This feature significantly influences the patients’ quality of life,
Carlo Perricone +13 more
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Background: (SLE) is a chronic autoimmune disease with a complex pathogenesis in which genes and environmental factors interact leading to a protean clinical picture. Joint involvement is one of the most common manifestations in SLE patients, with a prevalence ranging from 69 to 95%. This feature significantly influences the patients’ quality of life,
Carlo Perricone +13 more
openaire +1 more source
Immunologic Research, 2014
Anti-citrullinated protein antibodies (ACPA) are important serological markers in the diagnosis of rheumatoid arthritis (RA) and are part of the recent disease classification criteria. However, there is a strong need for reliable markers for measuring and predicting joint damage and disease activity.
Alvin, Yee +12 more
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Anti-citrullinated protein antibodies (ACPA) are important serological markers in the diagnosis of rheumatoid arthritis (RA) and are part of the recent disease classification criteria. However, there is a strong need for reliable markers for measuring and predicting joint damage and disease activity.
Alvin, Yee +12 more
openaire +3 more sources
Journal of Autoimmunity, 2017
In 2011 a novel autoantibody system, anti-carbamylated protein (anti-CarP) antibodies, was described in rheumatoid arthritis (RA) patients. Anti-CarP antibody positivity associates with a more severe disease course, is observed years before disease onset, and may predict the development of RA in arthralgia patients.
Verheul +9 more
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In 2011 a novel autoantibody system, anti-carbamylated protein (anti-CarP) antibodies, was described in rheumatoid arthritis (RA) patients. Anti-CarP antibody positivity associates with a more severe disease course, is observed years before disease onset, and may predict the development of RA in arthralgia patients.
Verheul +9 more
openaire +3 more sources
Development, 1985
ABSTRACT Gonadal development, germ cell differentiation and the appearance of membrane antigenic determinants, specific for male and female germ cells during gonadogenesis, was studied in larval and juvenile carp (Cyprinus carpio L.) until 25 weeks after fertilization.
Parmentier, H.K., Timmermans, L.P.M.
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ABSTRACT Gonadal development, germ cell differentiation and the appearance of membrane antigenic determinants, specific for male and female germ cells during gonadogenesis, was studied in larval and juvenile carp (Cyprinus carpio L.) until 25 weeks after fertilization.
Parmentier, H.K., Timmermans, L.P.M.
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Annals of the Rheumatic Diseases, 2017
Anti-carbamylated protein (anti-CarP) antibodies are reported to associate with more radiographic progression within the total rheumatoid arthritis (RA) population and anti-citrullinated peptide antibody (ACPA)-negative subgroup. We explored the association of anti-CarP with radiographic progression in RA and aimed to replicate the association and ...
Ajeganova +10 more
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Anti-carbamylated protein (anti-CarP) antibodies are reported to associate with more radiographic progression within the total rheumatoid arthritis (RA) population and anti-citrullinated peptide antibody (ACPA)-negative subgroup. We explored the association of anti-CarP with radiographic progression in RA and aimed to replicate the association and ...
Ajeganova +10 more
openaire +4 more sources
Annals of the Rheumatic Diseases, 2014
Background In inflammatory arthritis (IA) the spectrum varies from individuals “at-risk” to the full rheumatoid arthritis phenotype. ACPA are highly specific for RA and associated with severe progression. Recently, anti-carbamylated protein (anti-CarP) antibodies have been identified in the sera of individuals with RA and prior to diagnosis, predicting
L. Hunt +9 more
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Background In inflammatory arthritis (IA) the spectrum varies from individuals “at-risk” to the full rheumatoid arthritis phenotype. ACPA are highly specific for RA and associated with severe progression. Recently, anti-carbamylated protein (anti-CarP) antibodies have been identified in the sera of individuals with RA and prior to diagnosis, predicting
L. Hunt +9 more
openaire +1 more source
Annals of the Rheumatic Diseases, 2014
Background and Objectives In rheumatoid arthritis (RA), the presence of antibodies to citrullinated proteins (ACPA) is strongly associated with certain genetic risk factors and smoking. The recently identified antibodies against carbamylated proteins (anti-CarP) are present in part of ACPA-positive, but also ACPA-negative RA patients.
Xia Jiang +14 more
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Background and Objectives In rheumatoid arthritis (RA), the presence of antibodies to citrullinated proteins (ACPA) is strongly associated with certain genetic risk factors and smoking. The recently identified antibodies against carbamylated proteins (anti-CarP) are present in part of ACPA-positive, but also ACPA-negative RA patients.
Xia Jiang +14 more
openaire +1 more source