Results 61 to 70 of about 11,284 (188)
Possible Role of Anti-Cyclic Citrullinated Peptide Antibody (Anti-CCP Ab) in Rheumatic Diseases
Background: Anti-cyclic citrullinated peptide (anti-CCP) antibodies are highly specific for RA, but are not detectable in all RA patients, in addition their usefulness to identify rheumatic arthritis (RA) from other rheumatic diseases presenting with ...
Eman Sh Al-Obeidy +2 more
doaj +2 more sources
Comparative Evaluation of Rheumatoid Factor and Anti-CCP Antibody Tests as Diagnostic Markers for Rheumatoid Arthritis: A Cross-sectional Study from a Tertiary Care Centre in Dehradun, Uttarakhand, India [PDF]
Introduction: Rheumatoid Arthritis (RA) is a chronic autoimmune disease with a global prevalence of approximately 1%. It is characterised by persistent joint inflammation and the production of multiple autoantibodies, leading to joint destruction ...
Yogita Rawat +5 more
doaj +1 more source
Is anti-cyclic citrullinated peptide antibody a good value biomarker for alzheimer disease?
Background: Alzheimer′s disease (AD) is one of the most important neurodegenerative disorder. Anti-cyclic citrullinated peptide (anti-CCP) may all be involved in the development of vascular disease such as AD.
Rokhsareh Meamar +6 more
doaj
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo +8 more
wiley +1 more source
Abstract Background and aims Real‐world evaluation of clinical characteristics and treatment profile of patients with idiopathic pulmonary fibrosis (IPF) is needed to establish areas for improvement according to evidence‐based recommendations. This study evaluated the clinical characteristics and treatment profile of patients with IPF from the ...
Michelle Chee +31 more
wiley +1 more source
Incidence of P200 pemphigoid: A nationwide study
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen +7 more
wiley +1 more source
Autoimmunity and Periodontitis
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
The role of clathrin in post‐Golgi secretion in plant cells
Morphology of Arabidopsis thaliana XVE»amiCHC seedlings. Summary Within the plant endomembrane system, the vesicle coat protein clathrin localizes to the plasma membrane (PM) and the trans‐Golgi Network/early endosome (TGN/EE). While the role of clathrin in endocytosis at the PM is well established, its function at TGN/EE, presumably in late secretion (
Maciek Adamowski +4 more
wiley +1 more source
. Background:. Clinical outcomes of undifferentiated arthritis (UA) are diverse, and only 40% of patients with UA develop rheumatoid arthritis (RA) after 3 years.
Chun Li +44 more
doaj +1 more source
Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva +2 more
wiley +1 more source

