Results 101 to 110 of about 741 (163)

Detecting Borrelia burgdorferi–Triggered Seronegative Rheumatoid Arthritis Using [68Ga]Ga‐DOTA–Siglec‐9–Positron Emission Tomography/Computed Tomography

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Prince Dadson, Heli Ylä‐Outinen, Simona Malaspina, Mikko Koivumäki, Sirpa Jalkanen, Laura Pirilä, Anne Roivainen   +6 more
wiley   +1 more source

Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu, Yu Su, Li Zhou, Jianzhou Liu, Junchao Guo   +4 more
wiley   +1 more source

PD‐1hiCXCR5−CD4+T Peripheral Helper Cells Were Enriched and Potentially Predicted Clinical Response to Etanercept Therapy in Rheumatoid Arthritis

MedComm, Volume 7, Issue 8, August 2026.
This study investigated the role of PD‐1hiCXCR5−CD4+ T peripheral helper (Tph) cells in rheumatoid arthritis (RA). Tph cells were increased in the peripheral blood of RA patients and associated with disease activity. Baseline Tph cell levels were linked to the response to etanercept therapy.
Haojie Xu, Wanki Ho, Lulu Cao, Dongdong Fu, Yun Li, Feng Sun, Xi Xu, Zhanguo Li, Ru Li, Hua Ye, Huaqun Zhu   +10 more
wiley   +1 more source

The Role of Anti-cyclic Citrullinated Peptide Antibody from Joint to Brain

مجله دانشکده پزشکی اصفهان, 2014
Background: Anti-cyclic citrullinated peptide (CCP) antibodies are highly specific and predictive for rheumatoid arthritis (RA). Recently, existence of anti-CCP in several other inflammatory conditions from psoriatic arthritis to neurodegenerative ...
Rokhsareh Meamar, Mohammadreza Maracy, Majid Ghasemi, Mansour Salesi   +3 more
doaj  

The Role of Inflammation and Immunity in Cardiovascular Disease: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong, Zhen Wang, Xiaoxiao Lin, Ziwen Lei, Qianqian Huang, Hang Liu, Fei Luan, Junbo Zou, Yajun Shi   +8 more
wiley   +1 more source

The Association of Anti-Aminoacyl-Transfer Ribonucleic Acid Synthetase Antibodies in Patients With Rheumatoid Arthritis and Interstitial Lung Disease

The Turkish Journal of Gastroenterology, 2018
Objectives: This study aims to analyze the distribution and clinicopathological characteristics of anti-aminoacyl-transfer ribonucleic acid (tRNA) synthetase (ARS) antibodies in rheumatoid arthritis patients.
Masakazu MATSUSHITA, Naoto TAMURA, Michihiro OGASAWARA, Kurisu TADA, Ken YAMAJI, Yoshinari TAKASAKI   +5 more
doaj  

Association Between Chikungunya Infection and Rheumatoid Arthritis in Taiwan—A Cross‐Sectional Study

International Journal of Rheumatic Diseases, Volume 29, Issue 8, August 2026.
ABSTRACT Objectives Chikungunya virus (CHIKV) infection might cause chronic chikungunya arthritis resembling rheumatoid arthritis (RA). The purpose of this study is to investigate the potential role of this virus in the pathogenesis of RA in Taiwan, a non‐endemic area. Methods This cross‐sectional study enrolled 98 RA patients and 200 healthy controls.
Chang‐Yi Yen, Chang‐Chi Lin, Ping‐Chang Lin, Ching‐Yi Tsai, Li‐Teh Liu, Chen‐Hsuan Lin, Chun‐Hong Chen, Chia‐Chun Tseng, Hua‐Chen Chan, Cheng‐Chin Wu, Tsan‐Teng Ou, Jih‐Jin Tsai, Jeng‐Hsien Yen   +12 more
wiley   +1 more source

Anti‐Modified Protein Antibodies in Rheumatoid Arthritis: Pathogenic, Protective, or Passive Bystander?

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT The presence of anti‐modified protein antibodies (AMPA) is a hallmark of rheumatoid arthritis (RA). AMPA recognize post‐translationally modified proteins and are cross‐reactive. AMPA include anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA).
Amber‐Sarai F. L. Stalman, Diane van der Woude   +1 more
wiley   +1 more source

Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha, Holly M. Weisfelder, Thanh D. Do   +2 more
wiley   +1 more source

The TG2/LRP1 Pathway for T Cell Activation by Post‐Translationally Modified Antigens

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Post‐translational modifications (PTMs) can generate neo‐epitopes, modified peptides that evade immune tolerance and trigger immune responses. This review focuses on the TG2/LRP1 pathway as a new paradigm for coupling the formation of post‐translationally modified peptides with their effective presentation as T‐cell antigens by dendritic cells.
Agnele Sylvia Sewa, Fu‐Chen Yang, Chaitan Khosla   +2 more
wiley   +1 more source