Anti-cyclic citrullinated peptide antibodies are not associated with familial Mediterranean fever
Journal of Back and Musculoskeletal Rehabilitation, 2010Objective: This study investigated the presence of anti-cyclic citrullinated peptide (anti-CCP) antibodies in familial Mediterranean fever (FMF) patients and controls. Material and Methods: Forty-nine patients with FMF were enrolled (23 had a history of arthritis during attacks and 26 had no such history).
Yanmaz, Vefa +5 more
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Anti-Cyclic Citrullinated Peptide Antibodies in Patients with Juvenile Idiopathic Arthritis
Immunological Investigations, 2008The objectives were to determine the prevalence and clinical significance of anti-cyclic citrullinated peptide (anti-CCP) antibodies in patients with juvenile idiopathic arthritis (JIA). Anti-CCP antibodies were checked by ELISA in 68 children with JIA, 38 males and 30 females with mean age of 10.6 (+/-4.02) years and disease duration of 3.7 (+/-1.8 ...
H M, Habib, Y M, Mosaad, H M, Youssef
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[Anti-cyclic citrullinated peptide antibodies and rheumatoid arthritis].
Rinsho byori. The Japanese journal of clinical pathology, 2010Rheumatoid arthritis (RA) is a severe, progressive, systemic inflammatory disease of unknown etiology. Early diagnosis of RA is important to identify individuals who will develop severe destructive disease, so that effective treatment can be initiated before irreversible damage occurs.
Nobuhide, Hayashi, Shunichi, Kumagai
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Anti-cyclic citrullinated peptide antibodies in patients with sarcoidosis.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2016Anti-cyclic citrullinated peptide (anti-CCP) antibodies have a high predictive value in rheumatoid arthritis (RA) patients and are associated with disease severity. Sarcoidosis is a chronic inflammatory disease characterized by non-calcified granuloma formations.To determining the prevalence of anti-CCP antibodies in patients with sarcoidosis, and ...
Senol, Kobak +4 more
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Several autoantibodies found in RA are directed to epitopes in citrullinated proteins. One of them is anti modified citrullinated vimentin (Anti-MCV). We tested the value a newly developed ELISA for the detection of antibodies against a genetically modified citrullinated vimentin (anti-MCV) in comparison with an anti-CCP based ELISA system for the ...
Goksal, Keskin +6 more
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HLA-DRB1 and Anti-Cyclic Citrullinated Peptide Antibody Production in Rheumatoid Arthritis
International Archives of Allergy and Immunology, 2005Anti-cyclic citrullinated peptide antibodies (anti-CCP) are a new diagnostic marker for rheumatoid arthritis (RA), which shows a specificity of 97% and a sensitivity of 81% in the second generation assay. About 61% of RA patients express HLA-DRB1*0401.
Ilka, Senkpiehl +6 more
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Anti-cyclic citrullinated peptide autoantibodies in IgM rheumatoid factor-positive patients
Clinica Chimica Acta, 2005Antibodies to citrullinated proteins have been described in patients with RA and these appear to be the most specific markers of the disease. The objective of this study was to analyse the improvement in diagnostic accuracy of anti-cyclic citrullinated peptide autoantibodies and IgA rheumatoid factor in patients with clinical suspicion of RA and who ...
Belén, García-Berrocal +6 more
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Elevated Anti-Cyclic Citrullinated Peptide Levels Associated with Filamentary Keratitis
Ocular Immunology and InflammationTo assess two cases of filamentary keratitis with elevated serum levels of anti-cyclic citrullinated peptide (anti-CCP) antibodies without known rheumatoid arthritis (RA).A retrospective chart review was conducted on cases with filamentary keratitis and elevated anti-CCP antibodies between January 2021 and January 2023.
Kevin, Wang +4 more
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The predictive value of anti-cyclic citrullinated peptide antibodies in early arthritis.
The Journal of rheumatology, 2003To assess the additional predictive value of anti-cyclic citrullinated peptide (anti-CCP) antibodies above conventional variables for progressive erosive or disabling disease in a cohort of patients with early inflammatory oligo- and polyarthritis. Methods.
Jansen, Louise M.A. +5 more
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Are anti-cyclic citrullinated peptide antibodies pathogenic in rheumatoid arthritis?
Nature Clinical Practice Rheumatology, 2006New insights into the etiology of rheumatoid arthritis have suggested that humoral autoimmunity might have a substantive, possibly even causal role in the pathogenesis of disease. In this Viewpoint, Dr Holers will discuss the basis of this hypothesis, focusing on the role of anti-cyclic citrullinated peptide antibodies.
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