Results 221 to 230 of about 1,948,743 (254)

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Acute tree nut-triggered food protein-induced enterocolitis syndrome in two infants: a case report. [PDF]

Front Allergy
Nortier MR, Merks AM, van Boekholt AA, Herpertz ICEM, van der Heijden HHACM, Verweij MMJ.   +5 more
europepmc   +1 more source

Empowering Parents in Child Protection: An Evaluation of the Parental Advocacy and Information Service (PAIS) in Ireland

Child &Family Social Work, EarlyView.
ABSTRACT Parental advocacy represents a crucial response to the marginalization of parents within child protection systems, aiming to empower them by amplifying their voices, ensuring their participation and supporting them through complex legal and bureaucratic processes.
Shane Powell, Emilia Preter, Clive Diaz, Vicky Hansly   +3 more
wiley   +1 more source

Bullous Eruption Associated With Loncastuximab Tesirine in a Patient With Diffuse Large B‐Cell Lymphoma

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Loncastuximab tesirine (LT) is an antibody‐drug conjugate (ADC), a novel class of therapeutics that combines a target‐specific monoclonal antibody with a cytotoxic agent via a chemical linker. LT has been approved in the United States as therapy for relapsed or refractory diffuse large B‐cell lymphoma (DLBCL).
Daniella Jaguan, Cuong Nguyen, Jennifer N. Choi   +2 more
wiley   +1 more source

Outcomes of avoidance of routine nasogastric decompression following elective major gastrointestinal and hepatopancreatobiliary surgery: a single-center prospective observational cohort study. [PDF]

Ann Med Surg (Lond)
Parshaila R, Agarwal N, Dangi T, Yadav D, Nalbo D, Shrestha BC, Pandit N.   +6 more
europepmc   +1 more source

Impact of Opioid and Cannabis Use on Low-Dose Amitriptyline Efficacy in Cyclical Vomiting Syndrome: A Real-World Study in the United Kingdom. [PDF]

Neurogastroenterol Motil
Butt MF, Cefalo F, Sbarigia C, Dhali A, Corsetti M.   +4 more
europepmc   +1 more source

Component-based approach of enhanced recovery after surgery protocols in bariatric surgery: A systematic review and meta-analysis of randomized controlled trials. [PDF]

Metabol Open
Almaski IEM, Alalwani YJ, Alshammari RS, Alassiri RMA, Jathmi SAS, Alhadi AM, Alzahrani AS, Alzahrani MA, Azzam AY, Maani TA.   +9 more
europepmc   +1 more source

Perioperative glycaemic profiles in Aboriginal and Torres Strait Islander people with diabetes mellitus

Diabetic Medicine, EarlyView.
This large multicentre retrospective cohort study in Australia revealed that despite being younger and having greater preoperative comorbidity and higher HbA1c levels, Aboriginal and Torres Strait Islander adults with diabetes mellitus demonstrate higher rates of perioperative hypoglycaemia, but otherwise comparable markers of glycaemic variability and
Katerina Flabouris, Odette R. Pearson, Kim Morey, Suzanne M. Edwards, David R. Jesudason, Chinmay S. Marathe   +5 more
wiley   +1 more source

Peri-operative allergy: continuing to navigate uncertainty. [PDF]

Anaesthesia
Parkes A.
europepmc   +1 more source

Incretin‐Based Therapies as Cardiometabolic Interventions: Outcome Hierarchy, Receptor‐Network Pharmacology and Phenotype‐Based Clinical Positioning

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Incretin‐based pharmacotherapy was initially developed to improve glucose‐dependent insulin secretion and glycaemic control in type 2 diabetes, but its clinical interpretation has expanded substantially with cardiovascular outcome trials, kidney outcome data, obesity studies and next‐generation polyagonist development.
Ferenc Sztanek, Hajnalka Lőrincz, Mariann Harangi, Attila Csaba Nagy   +3 more
wiley   +1 more source