Results 81 to 90 of about 796 (295)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Zwitterionic polymer brush coatings with excellent anti-fog and anti-frost properties

RSC Advances, 2016
The anti-fog and anti-frost properties of superhydrophilic pSBMA and pSBVI polymer brushes compared to bare substrates.
Metwally Ezzat, Chun-Jen Huang
openaire   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Review on Interfacial Frosting and Anti-/Defrosting Techniques

Zhileng xuebao
Interfacial frosting is ubiquitous in daily life and has many industrial applications. Owing to the poor heat transfer performance induced by packed air pockets, the frost layer usually manifests itself as a thick porous medium, which compromises the ...
Cai Haoting, Zhang Ruimin, Zhao Yugang
doaj  

Ice‐Bridging Frustration by Self‐Ejection of Single Droplets Results in Superior Anti‐Frosting Surfaces

Advanced Materials Interfaces
Surfaces capable of delaying the frosting passively and facilitating its removal are highly desirable in fields where ice introduces inefficiencies and risks.
Nicolò G. Di Novo, Alvise Bagolini, Nicola M. Pugno   +2 more
doaj   +1 more source

Application of High-Surface Tension and Hygroscopic Ionic Liquid-Infused Nanostructured SiO₂ Surfaces for Reversible/Repeatable Anti-Fogging Treatment

Surfaces
Anti-fogging coatings/surfaces have attracted much attention lately because of their practical applications in a wide variety of engineering fields.
Satoshi Nakamura, Jerred Wassgren, Sayaka Sugie, Atsushi Hozumi   +3 more
doaj   +1 more source

Nanotextured Surfaces and Related Methods, Systems, and Uses [PDF]

A method of controlling wetting characteristics is described. Such method includes forming and configuring nanostructures on a surface where controlling of the wetting characteristics is desired. Surfaces and methods of fabricating such surfaces are also
Greer, Harold F., Greer, Julia R.
core   +1 more source

TEORI DAN PRAKTIK SISTEM AC (AIR CONDITIONER)

, 2023
Buku ini membahas tentang dasar teori air conditioner (AC), komponen sistem air conditioner (AC), pemeliharaan sistem AC, job sheet dan ...

core   +1 more source