Results 1 to 10 of about 74,969 (210)

Anti-GBM Disease in Pregnancy [PDF]

Journal of Investigative Medicine High Impact Case Reports, 2015
Antiglomerular basement membrane (GBM) disease presenting during pregnancy is uncommon. We present a case of a pregnant female who presented with acute renal failure requiring dialysis due to anti-GBM disease.
Mohammed Muqeet Adnan MD, Jordan Morton MD, Syed Hashmi MD, Sufyan Abdul Mujeeb DO, William Kern MD, Benjamin D. Cowley MD   +5 more
doaj   +3 more sources

Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report [PDF]

SAGE Open Medical Case Reports, 2023
Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh, Elham Kabiri Naeini, Firouzeh Moeinzadeh, Azar Naimi   +3 more
doaj   +4 more sources

Relationship Between Serum Complement C3 Levels and Outcomes Among Patients With Anti-GBM Disease [PDF]

Frontiers in Immunology, 2022
BackgroundIgG and complement 3 (C3) are generally found to be deposited along the glomerular basement membrane (GBM) in human anti-GBM disease. The pathogenic role of complement activation in kidney damage of anti-GBM disease has been explored in recent ...
Mengyue Zhu, Jingjing Wang, Weibo Le, Feng Xu, Ying Jin, Chenfeng Jiao, Haitao Zhang   +6 more
doaj   +4 more sources

Plasmapheresis, immunosuppressive therapy and anti-GBM disease prognosis: a cohort study of 107 patients [PDF]

Renal Failure
Background Anti-glomerular basement membrane (anti-GBM) disease presents with rapidly progressive glomerulonephritis and alveolar hemorrhage, requiring urgent management.
Ying Liu, Yiting Wu, Wei Wei, Letian Yang, Caihong Liu, Jian Li, Yongxiu Huang, Bo Wang, Yingying Yang, Ling Zhang, Ping Fu, Yuliang Zhao   +11 more
doaj   +4 more sources

Veno-venous extracorporeal membrane oxygenation (VV-ECMO) for life-threatening isolated pulmonary anti-GBM disease [PDF]

Respiratory Medicine Case Reports, 2022
Anti-glomerular basement membrane disease (anti-GBM disease) associated with renal and lung lesions has a poor prognosis. Diffuse alveolar hemorrhage (DAH) is a complication that worsens anti-GBM disease prognosis.
Shogo Goda, Satoshi Gando, Benjamin W. Berg   +2 more
doaj   +2 more sources

Anti-GBM disease with a mild relapsing course and low levels of anti-GBM autoantibodies [PDF]

CKJ: Clinical Kidney Journal, 2012
Anti-glomerular basement membrane disease (anti-GBM) is usually characterized by rapidly progressive glomerulonephritis, and when autoantibody production has ceased, relapses are rare. Here, we report a 71-year-old women diagnosed at a stage of mild renal insufficiency.
Marten Segelmark, J Wieslander, Segelmark Marten   +2 more
exaly   +3 more sources

Anti-GBM disease in pregnancy [PDF]

BMJ Case Reports
We present the case of a pregnant woman in her 20s who presented in her second trimester with severe pulmonary haemorrhage and dialysis-dependent acute kidney failure due to antiglomerular basement membrane (GBM) disease. Responding to therapy, she recovered kidney function and delivered a baby.
Abdul Hadi, Kafagi, Anna S, Li, David, Jayne, Silke R, Brix   +3 more
openaire   +3 more sources

A case of relapsing anti-GBM disease secondary to alemtuzumab therapy [PDF]

CEN Case Reports, 2023
AbstractWe report the first case of relapsing anti-GBM disease secondary to alemtuzumab in a 24-year-old female with relapsing–remitting multiple sclerosis. Initial anti-GBM disease was detected 10 months after alemtuzumab was given and was diagnosed by demonstrating high anti-GBM antibody titers and with a confirmatory kidney biopsy.
Saskia M. Leibowitz, Valli Manickam, Vikas Srivastava, George Kan   +3 more
openaire   +5 more sources

When Atypical Becomes Typical: A Fulminant Seronegative Anti-GBM Disease [PDF]

Kidney Medicine
Anti-glomerular basement membrane (GBM) disease is a rare autoimmune disorder characterized by circulating anti-GBM antibodies, rapidly progressive glomerulonephritis, and linear immunoglobulin G (IgG) deposition along the GBM. In contrast, atypical anti-
Faten Y. Andrawes-Barbara, George Jiries, Olga Vdovitch, Ofer Ben-Izhak, Etty Kruzel-Davila   +4 more
doaj   +2 more sources

Peroxidasin—a Novel Autoantigen in Anti-GBM Disease? [PDF]

Journal of the American Society of Nephrology, 2018
Basement membranes are highly specialized extracellular matrices, the evolution of which coincided with the emergence of multicellularity in animals. They associate with all epithelial and endothelial surfaces in the body, and they are essential for tissue morphogenesis both through provision ...
McAdoo, SP, Pusey, CD
openaire   +4 more sources