Relationship Between Serum Complement C3 Levels and Outcomes Among Patients With Anti-GBM Disease. [PDF]
Front Immunol, 2022 BackgroundIgG and complement 3 (C3) are generally found to be deposited along the glomerular basement membrane (GBM) in human anti-GBM disease. The pathogenic role of complement activation in kidney damage of anti-GBM disease has been explored in recent ...
Zhu M +6 more
europepmc +4 more sources
Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report. [PDF]
SAGE Open Med Case Rep, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kazemzadeh K +3 more
europepmc +4 more sources
Plasmapheresis, immunosuppressive therapy and anti-GBM disease prognosis: a cohort study of 107 patients. [PDF]
Ren FailBackground Anti-glomerular basement membrane (anti-GBM) disease presents with rapidly progressive glomerulonephritis and alveolar hemorrhage, requiring urgent management.
Liu Y +11 more
europepmc +4 more sources
Veno-venous extracorporeal membrane oxygenation (VV-ECMO) for life-threatening isolated pulmonary anti-GBM disease. [PDF]
Respir Med Case Rep, 2022 Anti-glomerular basement membrane disease (anti-GBM disease) associated with renal and lung lesions has a poor prognosis. Diffuse alveolar hemorrhage (DAH) is a complication that worsens anti-GBM disease prognosis.
Goda S, Gando S, Berg BW.
europepmc +2 more sources
A case of aggressive atypical anti-GBM disease complicated by CMV pneumonitis. [PDF]
BMC Nephrol, 2019 Background Anti-glomerular basement membrane (anti-GBM) disease is characterized by circulating IgG glomerular basement membrane antibodies and is clinically expressed as a rapidly progressive crescentic glomerulonephritis (GN), with 30–60% of patients ...
Sporinova B +6 more
europepmc +2 more sources
Clinical features and prognosis of patients with anti-GBM disease combined with mesangial IgA deposition. [PDF]
Front ImmunolIntroductionAnti-GBM diseases with IgA deposition in the mesangial region are rarely described.The factors influencing renal prognosis in patients with anti-GBM disease combined with mesangial IgA deposition are unknown.MethodsWe searched the ...
Ning W, Zhao YF, Liu YR, Qi YY, Zhao ZZ.
europepmc +2 more sources
Anti-GBM Disease in Pregnancy: Acute Renal Failure Resolved After Plasma Exchange, Hemodialysis, and Steroids. [PDF]
J Investig Med High Impact Case Rep, 2016 Antiglomerular basement membrane (GBM) disease presenting during pregnancy is uncommon. We present a case of a pregnant female who presented with acute renal failure requiring dialysis due to anti-GBM disease.
Adnan MM +5 more
europepmc +2 more sources
Rapidly progressive anti-GBM disease secondary to long-standing rheumatoid arthritis: a case report and literature review. [PDF]
Front ImmunolBackgroundLong-standing rheumatoid arthritis (RA) complicated by anti–glomerular basement membrane (anti-GBM) disease is exceptionally rare.CaseA 71-year-old man with long-standing seropositive RA developed a rapidly progressive glomerulonephritis due to
Li J +9 more
europepmc +2 more sources
Elevated serum soluble α3(IV)NC1 correlates with kidney injury and worse outcome in patients with anti-glomerular basement membrane disease. [PDF]
Front ImmunolBackgroundAnti-glomerular basement membrane (GBM) disease is the most severe form of autoimmune kidney diseases characterized by pathogenic autoantibodies against GBM component, α3(IV)NC1.
Kuang H, Wan HS, Cui Z, Zhao MH, Jia XY.
europepmc +2 more sources
The multiple autoantibodies in anti-GBM disease. [PDF]
Nephrol Dial TransplantPrendecki M, Pusey CD.
europepmc +4 more sources