Results 21 to 30 of about 89,994 (247)

A case report of atypical anti-glomerular basement membrane disease

BMC Nephrology, 2022
Background Anti-glomerular basement membrane (anti-GBM) disease is characterized by crescentic necrotizing glomerulonephritis, with linear deposits of immunoglobulin G (IgG) in the GBM.
Ryo Tamura, Toshiki Doi, Shuma Hirashio, Kensuke Sasaki, Yukinari Masuda, Akira Shimizu, Takao Masaki   +6 more
doaj   +1 more source

Anti-glomerular Basement Membrane Disease with Atypical Associations

Saudi Journal of Kidney Diseases and Transplantation, 2021
Anti-glomerular basement membrane (anti-GBM) disease is a systemic autoimmune disorder characterized by circulating immunoglobulin (Ig) G antibodies to carboxy-terminal, noncollagenous 1 domain of type IV collagen of GBM.
Prashant Bharat Malviya, Somashekhar Modigonda, Sanjay Maitra, Swarnalata Gowrishankar   +3 more
doaj   +1 more source

Atypical anti-glomerular basement membrane disease with anti-GBM antibody negativity and ANCA positivity: a case report

BMC Nephrology, 2021
Background Anti-glomerular basement membrane (anti-GBM) disease is an organ-specific autoimmune disease that involves the lung and kidneys and leads to rapid glomerulonephritis progression, with or without diffuse alveolar hemorrhage, and even ...
Na Guo, Qinghua Yin, Song Lei, Yanjun He, Ping Fu   +4 more
doaj   +1 more source

Serodiagnosis of Anti-glomerular Basement Membrane Disease Using a Newly Developed Chemiluminescence Immunoassay

Frontiers in Medicine, 2022
Circulating autoantibodies directed against the kidney glomerular basement membrane (GBM) antigens are important markers in the diagnosis and monitoring of autoimmune glomerulonephritides, including the classic Goodpasture's syndrome.
Alexander Kühnl, Lea Hartwig, Cornelia Dähnrich, Wolfgang Schlumberger   +3 more
doaj   +1 more source

Clinical and immunologic characteristics of Japanese patients with anti-glomerular basement membrane disease: case reports and literature review

Renal Replacement Therapy, 2021
Background Clinical studies of anti-glomerular basement membrane (GBM) disease were limited because of the low incidence. We aimed to report the characteristics, treatments, and outcomes of patients with anti-GBM disease at a tertiary reference medical ...
Yoshinosuke Shimamura, Takuto Maeda, Koki Abe, Yayoi Ogawa, Hideki Takizawa   +4 more
doaj   +1 more source

Unleashing the power of complement activation: unraveling renal damage in human anti-glomerular basement membrane disease

Frontiers in Immunology, 2023
Anti-glomerular basement membrane (GBM) disease is a rare but life-threatening autoimmune disorder characterized by rapidly progressive glomerulonephritis with or without pulmonary hemorrhage. Renal biopsies of anti-GBM patients predominantly show linear
Anqi Tang, Xin Zhao, Tian Tao, Dengpiao Xie, Bojun Xu, Youqun Huang, Mingquan Li   +6 more
doaj   +1 more source

Comparison of the performance of a chemiluminescence assay and an ELISA for detection of anti-GBM antibodies

Renal Failure, 2020
Objective Autoantibodies to the α3 chain noncollagen 1 domain of type IV collagen (α3(IV)NC1) are a serological hallmark in the diagnosis of anti-glomerular basement membrane (GBM) disease.
Ying Tan, Wei Pang, Xiaoyu Jia, Ming-hui Zhao   +3 more
doaj   +1 more source

SARS-CoV-2 infection and recurrence of anti-glomerular basement disease: a case report

BMC Nephrology, 2021
Background Anti-glomerular basement membrane disease (GBM) disease is a rare autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary haemorrhage.
Alexander Winkler, Emanuel Zitt, Hannelore Sprenger-Mähr, Afschin Soleiman, Manfred Cejna, Karl Lhotta   +5 more
doaj   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source

IgA mediated anti-glomerular basement membrane disease with associated circulating anti-neutrophil cytoplasm antibodies [PDF]

Journal of Nephropathology
Anti-glomerular basement membrane (anti-GBM) disease is an aggressive small vessel vasculitis usually mediated by IgG autoantibodies. We describe the case of a 73-year-old male with rapidly progressive renal failure that was diagnosed with IgA mediated ...
Patricia Alves, Mário Góis, Tiago Pereira, Dulce Carvalho, Fernando Nolasco   +4 more
doaj   +1 more source