Results 31 to 40 of about 74,493 (218)

A case of relapsing anti-GBM disease secondary to alemtuzumab therapy. [PDF]

open access: yesCEN Case Rep, 2023
AbstractWe report the first case of relapsing anti-GBM disease secondary to alemtuzumab in a 24-year-old female with relapsing–remitting multiple sclerosis. Initial anti-GBM disease was detected 10 months after alemtuzumab was given and was diagnosed by demonstrating high anti-GBM antibody titers and with a confirmatory kidney biopsy.
Leibowitz SM   +3 more
europepmc   +5 more sources

The Immunobiological Agents for Treatment of Antiglomerular Basement Membrane Disease

open access: yesMedicina, 2023
Combination therapy with glucocorticoids, cyclophosphamide, and plasmapheresis is recommended as the standard treatment for anti-glomerular basement membrane (anti-GBM) disease, but the prognosis of this disease remains poor.
Marina Yamashita   +3 more
doaj   +1 more source

The clinical and immunological features of the post-extracorporeal shock wave lithotripsy anti-glomerular basement membrane disease

open access: yesRenal Failure, 2021
Introduction Extracorporeal shock wave lithotripsy (ESWL) is a noninvasive modality to treat urolithiasis, with complications including tissue damage and hematoma of kidney parenchyma.
Beining Wang   +4 more
doaj   +1 more source

Clinicopathological characteristics and predictors of poor outcome in anti-glomerular basement membrane disease – a fifteen year single center experience

open access: yesRenal Failure, 2021
Introduction Anti-glomerular basement membrane (anti-GBM) disease is a small vessel vasculitis affecting the renal and lung capillary beds. We aim to study the clinicopathological characteristics and predictors of poor outcome of this disease in our ...
Zafirah Zahir   +3 more
doaj   +1 more source

Goodpasture’s Syndrome with Negative Anti-glomerular Basement Membrane Antibodies

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2017
A young male patient with rapidly progressive and life-threatening pulmonary haemorrhage due to anti-glomerular basement membrane (anti-GBM) antibody disease without renal involvement repeatedly tested negative for serum anti-GBM antibodies.
Tjitske Berends-De Vries   +5 more
doaj   +1 more source

Tolerance and Autoimmunity in Anti-GBM Disease [PDF]

open access: yesJournal of the American Society of Nephrology, 2003
Anti-glomerular basement membrane (GBM) or Goodpasture’s disease is an uncommon cause of acute renal failure, with an incidence of only 0.5–1 cases/million per year, making it an unfamiliar clinical entity to many physicians.
Alan D. Salama, Jeremy B. Levy
openaire   +1 more source

A Case of Simultaneous, Biopsy-Proven, Classic, ANCA-Positive Wegener's Granulomatosis and Anti-GBM Disease, but without Detectible Circulating Anti-GBM Antibodies

open access: yesThe Scientific World Journal, 2010
Wegener's granulomatosis (WG) is a systemic, necrotizing, granulomatous vasculitis of unknown etiology. Approximately 75% of cases present as classic WG with both pulmonary and renal involvement, while the remaining 25% of patients present with a limited
Aleksandra Gmurczyk   +5 more
doaj   +1 more source

Anti-glomerular basement membrane disease mediated by IgG and IgA: a case report

open access: yesRenal Failure, 2021
Background Anti-glomerular basement membrane (anti-GBM) disease is a rare autoimmune condition responsible for rapidly progressive glomerulonephritis. This disease is usually mediated by IgG autoantibodies against the noncollagenous domain of the α3(IV ...
Guming Zou   +4 more
doaj   +1 more source

Retransplantation in Alport post-transplant anti-GBM disease [PDF]

open access: yesKidney International, 2004
Post transplant anti-glomerular basement membrane (GBM) disease affects up to 5% of patients with Alport's syndrome. Defects in the COL4A5 gene are responsible for most cases, and alpha 5(IV)NC1 is the usual target for alloantibodies. Gene deletions are more commonly associated with this complication than are point mutations.
Browne, Gemma   +8 more
openaire   +3 more sources

The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients

open access: yesBMC Nephrology, 2011
Background Human leukocyte antigen (HLA) alleles are associated with many autoimmune diseases, including anti-glomerular basement membrane (GBM) disease.
Zhou Xu-Jie   +6 more
doaj   +1 more source

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