Results 41 to 50 of about 89,994 (247)
KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages [PDF]
, 2016 Among the strategies adopted by glioma to successfully invade the brain parenchyma is turning the infiltrating microglia/macrophages (M/MΦ) into allies, by shifting them toward an anti-inflammatory, pro-tumor phenotype.
Catalano, M +11 more
core +2 more sources
REGULATORY ROLE OF OX22HIGH T-CELLS IN MERCURY-INDUCED AUTOIMMUNITY IN THE BROWN NORWAY RAT [PDF]
, 1993 The monoclonal antibody OX22 defines a functional split within CD4+ T cells in the rat, with OX22high cells mainly producing interleukin 2 (IL-2) and interferon γ and responsible for delayed-type hypersensitivity responses, and OX22low cells mainly ...
Mathieson, PW, Oliveira, DB, Thiru, S
core +1 more source
The Scientific World Journal, 2010 Wegener's granulomatosis (WG) is a systemic, necrotizing, granulomatous vasculitis of unknown etiology. Approximately 75% of cases present as classic WG with both pulmonary and renal involvement, while the remaining 25% of patients present with a limited
Aleksandra Gmurczyk +5 more
doaj +1 more source
Anti-glomerular basement membrane disease mediated by IgG and IgA: a case report
Renal Failure, 2021 Background Anti-glomerular basement membrane (anti-GBM) disease is a rare autoimmune condition responsible for rapidly progressive glomerulonephritis. This disease is usually mediated by IgG autoantibodies against the noncollagenous domain of the α3(IV ...
Guming Zou +4 more
doaj +1 more source
An Atypical Case of Anti GBM Disease
Bangladesh Journal of Medicine, 2023 Anti GBM disease is a very rare type of small vessel vasculitis. The incidence is around less than 1 per million per year .This disease is also known as “Good Pasteur Disease”. Usually it presents with rapidly progressive glomerulonephritis with or without lung haemorrhage. The pathognomonic hallmark of the disease is strong linear IgG deposition along
Sabrina Shahrin, Al Mahmud, Babrul Alam
openaire +1 more source
KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment [PDF]
, 2016 Malignant gliomas are among the most frequent and aggressive cerebral tumors, characterized by high proliferative and invasive indexes. Standard therapy for patients, after surgery and radiotherapy, consists of temozolomide (TMZ), a methylating agent ...
Catalano, Myriam +13 more
core +3 more sources
Tolerance and Autoimmunity in Anti-GBM Disease [PDF]
Journal of the American Society of Nephrology, 2003 Anti-glomerular basement membrane (GBM) or Goodpasture’s disease is an uncommon cause of acute renal failure, with an incidence of only 0.5–1 cases/million per year, making it an unfamiliar clinical entity to many physicians.
Alan D. Salama, Jeremy B. Levy
openaire +1 more source
Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome [PDF]
, 2011 Background Pulmonary-renal syndrome associated with anti-glomerular basement membrane (GBM) antibodies, also known as Goodpasture's syndrome, is a rare but acute and life-threatening condition.
Christoph Etter +6 more
core +2 more sources
The role of the Bmi1-GSK3β pathway in glioblastoma [PDF]
, 2010 Malignant gliomas remain one of the deadliest of all cancers despite maximal therapy. They present unique challenges to therapy with a median survival of 12 months.
Korur, Serdar
core +1 more source
The Potential Roles of Long Noncoding RNAs (lncRNA) in Glioblastoma Development [PDF]
, 2016 Long noncoding RNA (lncRNA) may contribute to the initiation and progression of tumor. In this study, we first systematically compared lncRNA and mRNA expression between glioblastoma and paired normal brain tissues using microarray data.
Eischen, Christine M. +6 more
core +2 more sources