IgA Nephropathy and Atypical Anti-GBM Disease: A Rare Dual Pathology in a Pediatric Rapidly Progressive Glomerulonephritis. [PDF]
Bajaj V +5 more
europepmc +1 more source
SMPD1 expression varies across different glioma subtypes and clinical features and is associated with poor prognosis. High SMPD1 levels are linked to an immunosuppressive tumor microenvironment, characterized by suppressed M1 macrophage polarization and enhanced M2‐like signatures.
Yanan Xu +6 more
wiley +1 more source
An Updated Narrative Review on the Therapeutic Potential of Resveratrol in the Treatment of Cancer
ABSTRACT Background Cancer is a significant global health challenge, affecting millions of people every year. Overall survival rates have improved over time, but some patients exhibit treatment resistance, prompting ongoing research to find suitable and effective sensitizers.
Mohammad Ashraful Islam +6 more
wiley +1 more source
Pneumocystis pneumonia secondary to intensive immunosuppression treatment for anti-GBM disease complicated with IgA nephropathy: A case report and literature review. [PDF]
Zhang M +5 more
europepmc +1 more source
RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets
RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin +9 more
wiley +1 more source
Diagnosis of membranous nephropathy with Anti-GBM glomerulonephritis: a case series report
Background The concomitant occurrence of membranous nephropathy and anti-glomerular basement (anti-GBM) disease has been previously described but is extremely rare.
Ge Liu +5 more
doaj +1 more source
Antiglomerular basement membrane (anti-GBM) disease with clinical and histological features that bridge the typical to atypical spectrum. [PDF]
Fouhy F +3 more
europepmc +1 more source
Clinical Application of Peripheral Blood Biomarkers for Solid Tumors
Peripheral blood biomarkers provide a minimally invasive, dynamic, and potentially more accurate means to obtain a comprehensive tumor profile. Technologies for detecting them are advancing, and with the help of artificial intelligence, they are being used more and more often for cancer diagnosis, prognostic assessment, and therapeutic monitoring ...
Xinru Tu, Mengyan Tu, Junfen Xu
wiley +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Graphene Triggers Inflammation in Murine Microglia via Phagocytosis
Phagocytosis of single‐layer graphene by microglia triggers inflammatory activation without cytotoxicity. Small carbon nanotubes elicit similar responses, whereas larger graphene nanoplatelets do not. Proteomic analysis reveals effects on inflammation, cytoskeleton, and proliferation, highlighting the importance of graphene stability for safe neural ...
Pratika Rai +10 more
wiley +1 more source

