Results 131 to 140 of about 74,969 (210)
We investigated the habitat suitability and landscape connectivity of the endangered forest musk deer (Moschus berezovskii) at its northernmost known distribution limit using multi‐scale ensemble modeling and circuit theory. Our results highlight a scale‐dependent reliance on macro‐scale steep terrain and micro‐scale thermal refugia, while revealing ...
Wangshan Zheng +7 more
wiley +1 more source
ABSTRACT Background and Aims Solid tumors emerge from uncontrolled cell division and interactions with neighboring cells that influence their growth and resistance to therapy. Anti‐cancer drugs are developed to disrupt these processes, but they often damage healthy cells, making treatment difficult to manage safely and effectively. As the global cancer
Mohsin Kamran +3 more
wiley +1 more source
ABSTRACT Extracellular vesicles (EVs) mediate intercellular communication within the tumour microenvironment by carrying cargoes from paracrine parent cells. EVs have attracted great research interest for their ability to carry nucleic acids into recipient cells and modulate cellular functions.
Gaoge Sun +11 more
wiley +1 more source
The Dual Role of the Gut Microbiota in Cancer Chemoresistance
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi +3 more
wiley +1 more source
Glucose Transporter 1 in Health and Disease
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai +3 more
wiley +1 more source
Response to the Letter to the Editor Entitled "Atypical anti-GBM disease: A Case for the Occam's Razor? [PDF]
Fernández-Lorente L +1 more
europepmc +1 more source
Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge +5 more
wiley +1 more source
Concurrent anti-GBM disease and p-ANCA vasculitis presenting as pulmonary-renal syndrome in a patient with chronic kidney disease: a case report. [PDF]
Nazeer R +4 more
europepmc +1 more source
Nucleotide Metabolism in Health and Disease
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao +7 more
wiley +1 more source
Anti-GBM Disease Following Ovarian Mesonephric-Like Adenocarcinoma: A Unique Insight Into Paraneoplastic Autoimmunity. [PDF]
Fairhead T +3 more
europepmc +1 more source

