Results 131 to 140 of about 74,969 (210)

Assessing Habitat Suitability and Landscape Connectivity for the Endangered Forest Musk Deer (Moschus berezovskii) at Its Northern Distribution Margin: A Multi‐Scale Ensemble Approach

open access: yesEcology and Evolution, Volume 16, Issue 8, August 2026.
We investigated the habitat suitability and landscape connectivity of the endangered forest musk deer (Moschus berezovskii) at its northernmost known distribution limit using multi‐scale ensemble modeling and circuit theory. Our results highlight a scale‐dependent reliance on macro‐scale steep terrain and micro‐scale thermal refugia, while revealing ...
Wangshan Zheng   +7 more
wiley   +1 more source

Advancing Tumor Treatment Through Artificial Intelligence and Mathematical Modeling: A Comprehensive Review

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Solid tumors emerge from uncontrolled cell division and interactions with neighboring cells that influence their growth and resistance to therapy. Anti‐cancer drugs are developed to disrupt these processes, but they often damage healthy cells, making treatment difficult to manage safely and effectively. As the global cancer
Mohsin Kamran   +3 more
wiley   +1 more source

Tumour‐Derived Extracellular Vesicles Containing dsRNA Induce Degradation of Ribosomal Protein mRNA in Platelets

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
ABSTRACT Extracellular vesicles (EVs) mediate intercellular communication within the tumour microenvironment by carrying cargoes from paracrine parent cells. EVs have attracted great research interest for their ability to carry nucleic acids into recipient cells and modulate cellular functions.
Gaoge Sun   +11 more
wiley   +1 more source

The Dual Role of the Gut Microbiota in Cancer Chemoresistance

open access: yesMicrobiologyOpen, Volume 15, Issue 4, August 2026.
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi   +3 more
wiley   +1 more source

Glucose Transporter 1 in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai   +3 more
wiley   +1 more source

Turning Cold Tumors Into Hot Tumors: Implications for Cancer Therapy

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Barrier‐defined strategies for cold‐to‐hot tumor conversion. Cold tumors include immune‐desert and immune‐excluded states marked by poor antigen visibility, limited T‐cell priming, stromal or vascular exclusion, metabolic stress and suppressive immune programs.
Xiao Ge   +5 more
wiley   +1 more source

Nucleotide Metabolism in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao   +7 more
wiley   +1 more source

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