Results 151 to 160 of about 89,994 (247)

Efficacy and immunogenic effects of Tumor Treating Fields (TTFields) in preclinical models of pancreatic ductal adenocarcinoma, with and without gemcitabine/nab‐paclitaxel

open access: yesInternational Journal of Cancer, Volume 158, Issue 12, Page 3091-3100, 15 June 2026.
What's new? Adaptive immune responses are typically limited in pancreatic ductal adenocarcinoma, resulting in minimal efficacy of immune checkpoint inhibitors. Tumor Treating Fields (TTFields) therapy, which uses low‐intensity intermediate‐frequency electric fields to disrupt cancer cell processes, has been approved for certain cancers.
Tal Kan   +21 more
wiley   +1 more source

Physiology, pathology and therapeutic potential of microglial triggering receptor expressed on myeloid cells 2 signalling: A narrative update

open access: yesClinical and Translational Discovery, Volume 6, Issue 3, June 2026.
TREM2hi microglia and macrophages exert distinct roles in neurological diseases. Enhancing TREM2 signalling supports pathological protein or debris clearance and mitigates inflammation in Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, demyelination disorders and stroke, whereas blocking TREM2 may alleviate tauopathy and ...
Zhe Kong   +3 more
wiley   +1 more source

Diagnosis of membranous nephropathy with Anti-GBM glomerulonephritis: a case series report

open access: yesBMC Nephrology
Background The concomitant occurrence of membranous nephropathy and anti-glomerular basement (anti-GBM) disease has been previously described but is extremely rare.
Ge Liu   +5 more
doaj   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

open access: yesChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci   +5 more
wiley   +1 more source

MET fusions and splicing variants in glioma: a landscape integrating clinical, pathological, and survival features

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 3, May 2026.
Abstract MET alterations, including MET fusions and splicing variants (F/SVs), are linked to glioma progression, but the clinical features remain underexplored since the 2021 WHO classification of tumors of the CNS. We aimed to systematically depict the MET F/SVs and patient characteristics in a multicenter cohort focusing on clinical, pathological ...
Zheng Fang   +11 more
wiley   +1 more source

Advancements in Glioblastoma Multiforme Treatment: A Comprehensive Systematic Review and Meta‐Analysis

open access: yesBrain and Behavior, Volume 16, Issue 5, May 2026.
This study is a systematic review and meta‐analysis comparing bevacizumab‐, temozolomide‐, and lomustine‐based treatments for recurrent glioblastoma. The findings suggest that monotherapy, particularly bevacizumab, may provide better clinical outcomes with fewer adverse events than combination regimens. ABSTRACT Background Glioblastoma multiforme (GBM)
Kayode Agboola   +6 more
wiley   +1 more source

The anti-GBM disease: treatments and outcomes [PDF]

open access: yesOA Nephrology, 2013
K Yamagata, K Hirayama
openaire   +1 more source

PLA2R‐Positive Membranous Nephropathy and AA Amyloidosis in an Ethiopian Patient With Chronic Hepatitis B: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT The coexistence of primary phospholipase A2 receptor positive membranous nephropathy and AA amyloidosis in a patient with chronic hepatitis B is an exceedingly rare triad presenting a profound diagnostic and therapeutic challenge. A 38‐year‐old Ethiopian man with nephrotic syndrome and chronic hepatitis B had dual pathology on renal biopsy ...
Betelhem Abreham   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy