Recurrent anti-GBM disease with T-cell large granular lymphocytic leukemia: A case report. [PDF]
Zhang M +6 more
europepmc +1 more source
This study integrated arterial stiffness with peripheral TCRβ repertoire and single‐cell transcriptomics in adults without cardiovascular disease, revealing a CD4+ T cell–driven “vascular immune remodeling” trajectory distinct from classical immunosenescence: increased TCR diversity, broad expansion of low‐frequency public clones and virus‐associated ...
Yu Miao +9 more
wiley +1 more source
tVNS Mitigates Neuroinflammation and Nociception in a Rodent LPS Endotoxemia Model
Experimental design and key findings. Four groups (Control+Sham, Control+tVNS, LPS+Sham, LPS+tVNS; n = 7 each) underwent serum ELISA, brain Western blot, and behavioral testing. tVNS altered serum Haptoglobin, IL‐6, CGRP1, and VE‐Cadherin levels, reversed LPS‐induced increases in brain IL‐1β, HMGB1, Haptoglobin, PAR‐2, and CGRP, and alleviated LPS ...
Kerem Atalar +10 more
wiley +1 more source
Clustering of Anti-GBM Disease: Clues to an Environmental Trigger? [PDF]
McAdoo SP, Pusey CD.
europepmc +1 more source
ABSTRACT This study aimed to elucidate the mechanism of action of Schisandrin A in the intervention of triple‐negative breast cancer (TNBC). Through the application of network pharmacology and the integration of targets from multiple databases, the research identified 128 overlapping targets between Schisandrin A and TNBC.
Meng Xu +6 more
wiley +1 more source
Molecular Analysis of Goodpasture's Disease Following Hematopoietic Stem Cell Transplant in a Pediatric Patient, Recalls the Conformeropathy of Wild-Type Anti-GBM Disease. [PDF]
Gray PE +10 more
europepmc +1 more source
Role of infection and molecular mimicry in the pathogenesis of anti-GBM disease [PDF]
openaire +2 more sources
ABSTRACT Melatonin signalling, mediated by membrane receptors and tightly regulated biosynthetic enzymes, is a key component of circadian and neuroendocrine control in the brain. However, whether the tryptophan–melatonin axis remains hierarchically intact during glioma progression and how its disruption affects downstream signalling remain unclear.
Bo Tan +11 more
wiley +1 more source
A case of PR3-ANCA-positive anti-GBM disease associated with intrarenal arteritis and thrombotic microangiopathy. [PDF]
Manabe S +6 more
europepmc +1 more source
Successful treatment of steroid-refractory double-positive ANCA and anti-GBM disease with a combination of plasma exchange and immunosuppression: A case report and literature review. [PDF]
Uto K +4 more
europepmc +1 more source

