Results 171 to 180 of about 74,969 (210)
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American Journal of Kidney Diseases, 2018
Patients with both anti-glomerular basement membrane (anti-GBM) disease and Castleman disease have been rarely reported. In this study, we report 3 patients with this combination. They had immunologic features similar to patients with classic anti-GBM disease. Sera from the 3 patients recognized the noncollagenous (NC) domain of the α3 chain of type IV
Su-Xia Wang, Qiu-Hua Gu, Zhao Cui
exaly +3 more sources
Patients with both anti-glomerular basement membrane (anti-GBM) disease and Castleman disease have been rarely reported. In this study, we report 3 patients with this combination. They had immunologic features similar to patients with classic anti-GBM disease. Sera from the 3 patients recognized the noncollagenous (NC) domain of the α3 chain of type IV
Su-Xia Wang, Qiu-Hua Gu, Zhao Cui
exaly +3 more sources
“Atypical” Anti-GBM Disease: Just Atypical, or Not Anti-GBM Disease at All?
American Journal of Kidney DiseasesTwo large cohorts1,2 of patients with “atypical” anti–glomerular basement membrane (GBM) disease sharedheterogeneous clinical presentations and a single commoninclusioncriterion—linearIgGstainingalongthe GBM, foundonbiopsy. Indeed,4patientsevendemonstratedanti-GBMantibodies, deemedrelevantforthediagnosisof“typical”anti-GBMdis ease ...
Vanja Ivković +2 more
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Atypical anti-GBM disease in pregnancy
BMJ Case ReportsA woman in her 20s presented with nephrotic syndrome and hyperemesis in early pregnancy. Pertinent initial investigations revealed a severe acute kidney injury, a serum albumin of 19 g/L, a random protein creatinine ratio of 800 g/mol and microscopic haematuria.
Shaun Chandler +1 more
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Anti-GBM disease and ANCA during dengue infection
Clinical Nephrology, 2015Anti-glomerular basement membrane (GBM) disease is a severe inflammatory renal disorder due to pathogenic autoantibodies directed mainly against the α3 chain of type IV collagen. In ~1/4 of patients with anti-GBM disease, antineutrophil cytoplasmic antibodies (ANCA) predominantly with myeloperoxidase (MPO) specificity can be detected.
Karlo J, Lizarraga +7 more
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Plasma Exchange in Anti-GBM Disease
1981The last two decades have witnessed a striking increase in knowledge of immunological mechanisms responsible for allergic glomerular injury. One particular type has received much attention — that in which disease is caused by the development of auto-antibodies to glomerular basement membrane (GBM).
D. K. Peters, M. Lockwood
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Lambda-Light-Chain-Mediated Anti-GBM Disease
Nephron, 2008A 77-year-old man presented with macroscopic haematuria and oligo-anuric renal failure. A renal biopsy showed moderate linear glomerular basement membrane (GBM) staining with λ light chains alone, but both circulating IgG and λ light chain activity were present. There was no evidence of a serum or urinary paraprotein and a bone marrow biopsy was normal.
J A, Savige +3 more
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Glomerular Basement Membrane and Anti-GBM Antibody Disease
Nephron, 2008The GBM is an important structure for the development of immunologic renal disease. It may serve as the primary antigen or as the site of deposition of immune complexes. The GBM is recognized as the major protein filtration barrier of the glomerulus.
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Rituximab in anti-GBM disease: A retrospective study of 8 patients
Journal of Autoimmunity, 2015Anti-glomerular basement membrane (GBM) disease is a rare autoantibody-mediated disorder presenting as rapidly progressive glomerulonephritis, and often with pulmonary hemorrhage. Antibody removal with plasmapheresis and immunosuppressive drugs are the cornerstones of the treatment.
Maxime, Touzot +11 more
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