Results 181 to 190 of about 6,619,911 (229)

POFUT1 Serves as an Independent Prognostic Factor and Therapeutic Target by Activating the PI3K/AKT Pathway in Glioma

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objective Protein O‐fucosyltransferase 1 (POFUT1) has been implicated in several malignancies, but its functional and prognostic significance in glioma remains insufficiently defined. This study evaluated whether POFUT1 expression is associated with glioma progression, patient outcome, and PI3K/AKT pathway activity.
Kai Yang, Chunlei Ju, Yifan Wang, Aijie Guo, Xiaochen Yang, Yang Mi, Yifei Su, Chunhong Wang, Hongming Ji   +8 more
wiley   +1 more source

Recurrent anti-GBM disease with T-cell large granular lymphocytic leukemia: A case report. [PDF]

Medicine (Baltimore), 2019
Zhang M, Guan N, Zhu P, Chen T, Liu S, Hao C, Xue J.   +6 more
europepmc   +1 more source

Development and Validation of an Interpretable Machine Learning Model for Predicting Early Pulmonary Metastasis Risk in Osteosarcoma

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Introduction Pulmonary metastasis in high‐grade conventional osteosarcoma remains a leading cause of treatment failure and mortality. Traditional monitoring methods are insufficient for early detection. This study aims to develop and validate an interpretable machine learning (ML) model using multi‐dimensional data from electronic medical ...
Jianhua Mu, Yitian Wang, Han Liu, Xuanhong He, Zhuangzhuang Li, Yi Luo, Yong Zhou, Minxun Lu, Fan Tang, Li Min, Chongqi Tu   +10 more
wiley   +1 more source

Spatial Omics in High‐Grade Gliomas: Mapping Immune–Tumor Niches for Precision Therapy

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT High‐grade gliomas (HGGs), particularly glioblastoma (GBM), remain among the most lethal human cancers despite decades of molecular profiling and therapeutic innovation. A primary reason for treatment failure is that HGG biology is spatial: malignant cell states, immune suppression, metabolic stress, and therapeutic resistance are organized ...
Saniyah Shaikh, Thaabit Raziq, Sulaf B. Alfares, Touleen T. Raslan, Ismail A. Abdullah, Itika Arora, Shamsa Saleh, Mohammed Imran Khan, Ahmed Yaqinuddin   +8 more
wiley   +1 more source

Clustering of Anti-GBM Disease: Clues to an Environmental Trigger? [PDF]

Clin J Am Soc Nephrol, 2016
McAdoo SP, Pusey CD.
europepmc   +1 more source

Hydrocephalus and Diffuse Alveolar Hemorrhage as the Initial Manifestation of Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many systems, such as the central nervous system (CNS), cardiovascular, musculocutaneous, renal, and respiratory systems, etc. SLE can occur alone or in association with other autoimmune diseases, especially antiphospholipid syndrome (APS).
Ehsan Adib, Narges Gorbanmaleki, Amirreza Eterafi, Sara Jalali Jivan   +3 more
wiley   +1 more source

Molecular Analysis of Goodpasture's Disease Following Hematopoietic Stem Cell Transplant in a Pediatric Patient, Recalls the Conformeropathy of Wild-Type Anti-GBM Disease. [PDF]

Front Immunol, 2019
Gray PE, McCarthy H, Siggs OM, Saleem MA, O' Brien T, Frith K, Ziegler JB, Kitching AR, Fogo AB, Hudson BG, Pedchenko V.   +10 more
europepmc   +1 more source

Favorable Neurological Outcome Following Prolonged Super‐Refractory Status Epilepticus in a Resource‐Limited Setting: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Super‐refractory status epilepticus (SRSE) is associated with high mortality and poor neurological outcomes. This case highlights a young male treated for SRSE. Diagnosis and treatment were expansive. Despite the severity of the patient's disease course, the patient had a favorable neurological outcome at the end of his hospital stay.
Amanda Sang, Allana Yearwood, Keevan Singh, Vaughn Lalla, Kamille Abdool   +4 more
wiley   +1 more source

Recurrent anti-GBM disease with pulmonary artery aneurysms. [PDF]

JRSM Open, 2016
Dixon J, Wilkinson H, Iqbal K, Quan V.
europepmc   +1 more source

Comprehensive In Silico Analysis Identifies MSTO1 and LIG1 as Candidate Biomarkers With Diagnostic and Prognostic Relevance in Hepatocellular Carcinoma

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and remains a major cause of cancer‐related mortality worldwide. Its poor clinical outcomes are largely attributed to late‐stage diagnosis and the limited accuracy of currently available diagnostic and prognostic biomarkers.
Jana Hamad, Hussein Fayyad‐Kazan, Fadi Abdel‐Sater   +2 more
wiley   +1 more source