Results 141 to 150 of about 6,619,911 (229)

IgA Nephropathy and Atypical Anti-GBM Disease: A Rare Dual Pathology in a Pediatric Rapidly Progressive Glomerulonephritis. [PDF]

Glomerular Dis, 2022
Bajaj V, Thakur S, Barwad A, Sinha A, Bagga A, Singh G.   +5 more
europepmc   +1 more source

The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma

Immunology &Cell Biology, EarlyView.
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald, Matthew Drill, Padmakrishnan C. Jayakrishnan, Richard P. Sequeira, Terence J. O'Brien, Rosalind L. Jeffree, Mastura Monif   +6 more
wiley   +1 more source

Artificial Intelligence‐Driven Precision Bisphosphonate Therapy in Osteoporosis: Mechanisms, Clinical Applications, Risks, and Future Directions

Orthopaedic Surgery, EarlyView.
This comprehensive review integrates 17 benchmark studies to illustrate the transition of osteoporosis management toward precision medicine. The schematic highlights three key clinical applications: AI‐driven opportunistic screening from routine CTs, precision pharmacotherapy selection, and the predictive prevention of adverse events like MRONJ ...
Xiang Yao, Yicong Chao, Xiao Gu, Jingtao Peng, Jishan Yuan, Wei Shi, Fuguo Zhang, Qiwen Bao   +7 more
wiley   +1 more source

Diagnosis of membranous nephropathy with Anti-GBM glomerulonephritis: a case series report

BMC Nephrology
Background The concomitant occurrence of membranous nephropathy and anti-glomerular basement (anti-GBM) disease has been previously described but is extremely rare.
Ge Liu, Xinyan Feng, Shuangyan Yu, Jie Sheng, Chunyan Liu, Lihua Wang   +5 more
doaj   +1 more source

Pneumocystis pneumonia secondary to intensive immunosuppression treatment for anti-GBM disease complicated with IgA nephropathy: A case report and literature review. [PDF]

Medicine (Baltimore), 2021
Zhang M, Yang D, Wang W, Zhao F, Zhang X, Li X.   +5 more
europepmc   +1 more source

Impact of ICD Presence in Patients With Left Ventricular Assist Devices for End‐Stage Heart Failure

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background The prognostic relevance of implantable cardioverter defibrillator (ICD) in patients with end‐stage heart failure (HF) with left ventricular assist device (LVAD) remains controversial. Objectives To evaluate the prognostic impact of ongoing use of ICD and associated complications in HF‐patients with LVAD‐implantation.
Nafilah Baridwan, Mustafa Gerçek, Muhammed Gerçek, Michiel Morshuis, Thomas Eitz, René Schramm, Volker Rudolph, Jan F. Gummert, Philipp Sommer, Christian Sohns, Angelika Costard‐Jäckle, Guram Imnadze   +11 more
wiley   +1 more source

Antiglomerular basement membrane (anti-GBM) disease with clinical and histological features that bridge the typical to atypical spectrum. [PDF]

BMJ Case Rep, 2021
Fouhy F, Mayer N, Burke L, O'Shaughnessy M.   +3 more
europepmc   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

High Endothelial Venules in Small Cell Lung Cancer: Prognostic Subtypes and Therapeutic Implications for Immunoradiotherapy

International Journal of Cancer, Volume 159, Issue 9, Page 2314-2327, 1 November 2026.
ABSTRACT Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine malignancy with an immunosuppressive tumor microenvironment, and current immunotherapy provides limited benefit. This highlights the need to identify microenvironmental features enabling effective immune responses.
Jiatian Fang, Zilian Wang, Hui Wang, Jianxin Xue, Kai Kang   +4 more
wiley   +1 more source