Results 121 to 130 of about 24,523 (202)

Successful treatment of steroid-refractory double-positive ANCA and anti-GBM disease with a combination of plasma exchange and immunosuppression: A case report and literature review

Respiratory Medicine Case Reports, 2018
The concurrence of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and anti-glomerular basement membrane (GBM) disease, known as double-positive disease, is rare, but it occurs at a much higher frequency than expected by chance ...
Kazuko Uto, Shigehisa Yanagi, Hironobu Tsubouchi, Nobuhiro Matsumoto, Masamitsu Nakazato   +4 more
doaj   +1 more source

Heparanase inhibition prevents glycocalyx damage and albuminuria in experimental minimal change disease

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Michael Crompton, Raina D. Ramnath, Kai Betteridge, Sara Desideri, Aldara Martin Alonso, Lulu Jiang, Monica Gamez, Holly Stowell‐Connolly, Viktoriia Vasylchenko, Karen L. Onions, Matthew J. Butler, Chris R. Neal, Andrew H. J. Salmon, Jeremy E. Turnbull, Hiroshi Kawachi, Olga V. Zubkova, Gavin I. Welsh, Simon C. Satchell, Rebecca R. Foster   +18 more
wiley   +1 more source

Empagliflozin and renal histological changes in an experimental model of heart failure in male rats

Physiological Reports, Volume 14, Issue 12, June 2026.
In a non‐diabetic rat model of heart failure, empagliflozin preserved renal structure by attenuating renal changes associated with congestion and tubular atrophy, while modulating inflammatory cell infiltration, characterized by increased CD206‐positive macrophages and reduced CD3‐positive T cells.
Aline Cavalcanti Toledo Wisnivesky, João Guilherme Ferreira Bertacchi, Bruno Caramelli   +2 more
wiley   +1 more source

Neuregulin‐1 Mitigates Kidney Injury in Humanized Sickle Cell Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Compared with untreated sickle cell (HbSS) mice, neuregulin‐1 (NRG‐1) treatment reduced plasma heme, lactate dehydrogenase, and pro‐inflammatory cytokines while increasing the proportion of circulating F‐cells. NRG‐1 improved urinary biomarkers of kidney health, decreasing cystatin C and NGAL levels and increased renal repair markers clusterin and ...
William K. Agbozo, Wesley Solomon, Isaac Joe Erskine, Cecilia E. Lekpor, Oguljahan Babayewa, Alaijah Bashi, Adriana Harbuzariu, Aqua Asberry, Driss Adel, Samuel Adjei, Lily Paemka, Solomon F. Ofori‐Acquah, Jonathan K. Stiles   +12 more
wiley   +1 more source

Targets of alloantibodies in Alport anti-glomerular basement membrane disease after renal transplantation

, 1998
Targets of alloantibodies in Alport anti-glomerular basement membrane disease after renal transplantation. A minority of patients with Alport syndrome develop anti-GBM disease in their allografts after renal transplantation. Clinically, the renal disease
Gubler, Marie Claire, Turner, A. Neil, Brainwood, David, Kashtan, Clifford   +3 more
core   +1 more source

Angiopoietin correlates with glomerular capillary loss in anti-glomerular basement membrane glomerulonephritis

, 2002
Angiopoietin correlates with glomerular capillary loss in anti-glomerular basement membrane glomerulonephritis.BackgroundEmerging evidence suggests that endothelial turnover occurs in several glomerular diseases and correlates with resolution or ...
Li, Xiao Zhong, Long, David A., Woolf, Adrian S., Tipping, Peter G., Yuan, Hai Tao   +4 more
core   +1 more source

Anti-glomerular basement membrane disease, ulcerative colitis, and primary sclerosing cholangitis: link or co-incidence?

, 2010
International audienceUlcerative colitis, primary sclerosing cholangitis, and anti-glomerular basement membrane disease (anti-GBM) are three rare immune diseases with incompletely under-stood pathogenic mechanisms.
Bouguen, Guillaume, Nathalie Rioux-Leclercq, Cecile Vigneau, Pinçon, Emilie, Rivalan, Joseph, Guillaume Bouguen, Le Pogamp, Patrick, Joseph Rivalan, Rioux-Leclercq, Nathalie, Emilie Pinçon, Vigneau, Cecile, Coiffier, Guillaume, Guillaume Coiffier, Patrick Le Pogamp   +13 more
core   +1 more source

Efficacy and Safety of Rituximab in Antiglomerular Basement Membrane Disease

Kidney International Reports
Introduction: Anti–glomerular basement membrane (GBM) disease is caused by pathogenic antibodies usually targeting the noncollagenous domain of the α3 chain of type IV collagen and frequently presents as rapidly progressive glomerulonephritis and diffuse
Vanja Ivković, Ingeborg Bajema, Annette Bruchfeld, Stephen McAdoo, Asheesh Kumar, Richard Klaus, Nele Kanzelmeyer, Maxime Touzot, Georgina Maalouf, Ajay Jaryal, Sanjay Vikrant, Dieter Haffner, Bärbel Lange-Sperandio, David Saadoun, Mårten Segelmark, Andreas Kronbichler   +15 more
doaj   +1 more source

CXCL16 and oxLDL are induced in the onset of diabetic nephropathy

, 2009
Diabetic nephropathy (DN) is a major cause of end-stage renal failure worldwide. Oxidative stress has been reported to be a major culprit of the disease and increased oxidized low density lipoprotein (oxLDL) immune complexes were found in patients with ...
Amann, Kerstin Ute, El Sayed, El Sayed M., Doberstein, Kai, Kämpfer-Kolb, Nicole, Abdel-Aziz, Abdel-Aziz H., Schäfer, Liliana, Gutwein, Paul, Pfeilschifter, Josef, Abdel-Bakky, Mohamed Sadek, Beckmann, Janet, Doller, Anke, Schramme, Anja   +11 more
core   +1 more source

Anti-glomerular basement membrane antibody-induced glomerulonephritis

, 1973
Anti–glomerular basement membrane antibody-induced glomerulonephritis. Sixty-three glomerulonephritic patients with evidence of anti–glomerular basement membrane (GBM) antibody by immunofluorescence, elution of specific antibody and/or detection of ...
Wilson, Curtis B., Dixon, Frank J.
core   +1 more source