Results 61 to 70 of about 2,254,901 (137)

Breast Cancer: Molecular Pathogenesis, Targeted Therapy, Screening, and Prevention

MedComm, Volume 7, Issue 1, January 2026.
The review manuscript examines the molecular pathogenesis, screening, prevention advances, and evolving targeted therapies in breast cancer. It highlights the integration of AI and multiomics for precision prevention and personalized treatment, pointing toward future directions in equitable cancer care.
Huijun Lei, Jinzhen Fu, Wei Gu, Hongjin Qiao, Huixue Guo, Zijian Chen, San Ming Wang, Tianhui Chen   +7 more
wiley   +1 more source

[Oestrus suppression in a dairy herd by means of anti-GnRH vaccination Improvac®: A prospective field study]. [PDF]

, 2020
INTRODUCTION The aim of this study was to evaluate the duration of estrus suppression after a double administration of the anti-GnRH vaccine Improvac® (Zoetis Schweiz GmbH, 2800 Delémont) in cows.
Hirsbrunner, Gabriela, Studer, Eveline, Schmid, Robin Michael   +2 more
core   +2 more sources

Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders

Poultry Science
To investigate the regulatory mechanism mediated by hypothalamic OPN5 on seasonal changes in the reproductive activities of domestic geese, 60 Magang ganders in their breeding period were selected for the experiment and evenly divided into an ...
Jianqiu Pan, Xu Shen, Hongjia Ouyang, Junfeng Sun, Sui Liufu, Danli Jiang, Wenjun Chen, Siyue Peng, Danning Xu, Yunbo Tian, Yunmao Huang, Jianhua He   +11 more
doaj   +1 more source

Update and new advances in fertility preservation and cancer

CA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 602-629, November/December 2025.
Abstract Adolescents and young adults with a cancer diagnosis face unique challenges during treatment and into survivorship related to fertility and family building. This review provides an updated overview of the impact of cancer and its associated treatments, including novel treatments in male and female fertility.
Gwendolyn P. Quinn, Michelle Bayefsky, Brooke Cherven, Lauren V. Ghazal, Kara N. Goldman, Nina Francis Levin, Leena Nahata, Bobby Najari, Sameer Thakker, Daniel R. Greenberg, Joshua A. Halpern, Susan T. Vadaparampil   +11 more
wiley   +1 more source

Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis

, 2020
Tuberculosis still claims more lives than any other pathogen, and a vaccine better than BCG is urgently needed. One of the challenges for novel TB vaccines is to protect against all Mycobacterium tuberculosis lineages, including the most virulent ones ...
권기웅, 신성재
core   +1 more source

Cancer and fertility management: FIGO best practice advice

International Journal of Gynecology &Obstetrics, Volume 171, Issue 1, Page 32-44, October 2025.
Abstract Cancer diagnoses in patients of reproductive age require balancing urgent oncological treatment with the need to preserve fertility. This FIGO Best Practice Advice outlines key considerations for fertility management in this population given the rising cancer incidence among young women and the reproductive risks posed by cancer treatments ...
Nikhil Purandare, Francisco Ruiloba, Long Nguyen‐Hoang, Sarikapan Wilailak, Nozomu Yanaihara, Jacqueline P. W. Chung, Jaideep Malhotra, Edgar Mocanu, Frédéric Amant, Orla McNally, Inge Peters, Katie Flynn, Aya El Helali, Cynthia Maxwell, Sumaiya Adam, Lina Bergman, Surabhi Nanda, Valerie Tiempo Guinto, Fionnuala M. McAuliffe, Catherine Nelson‐Piercy, Melanie Nana, Graeme Smith, Jonathan Berek, Sharleen O'Reilly, Pat O'Brien, Bo Jacobsson, Liona C. Poon, on behalf of the FIGO Committee on the Impact of Pregnancy on Long‐term Health and the FIGO Division of Maternal and Newborn Health and in collaboration with the FIGO Committee on Women's Cancer and the FIGO Committee on Reproductive Medicine, Endocrinology and Infertility   +28 more
wiley   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, Volume 8, Issue 9, September 2025.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Immunization of Female Mice with a Plasmid DNA Vaccine Coding EightRepeats of Gonadotrophin Releasing Hormone (Gnrh-I) and Eight T-HelperEpitopes Suppress Fertility In Vivo [PDF]

, 2015
Induction of an appropriate immune response against gonadotrophin releasing hormone (GnRH-I) disrupt fertility,reduce fecundity and regress tumours of reproductive system.To disrupt fertility a plasmid DNA vaccine wasengineered coding eight repeats of ...
Gebril, Ayman M, Islam, Mohammad, Khan, Mohammad, Rima, Umme, Ferro, Valerie, Kimura, Tadashi, Bari, Abu   +6 more
core   +2 more sources

A 5-year follow-up of antibody response in children vaccinated with single dose of live attenuated SA14-14-2 Japanese encephalitis vaccine: immunogenicity and anamnestic responses

, 2008
Out of 98 subjects who had participated in the 2000 JE vaccination campaign, 69 people were enrolled in the tests of 2004 and 2005 for the evaluation of long term immune response of a single dose of live attenuated SA14-14-2 JE vaccine.
오희철
core   +1 more source

Anti-cancer activity of plant-produced HPV16 E7 vaccine

, 2022
S.3018-3021The E7 oncoprotein from Human Papilloma Virus (HPV) is an attractive candidate for anti-cancer vaccine development. In this study, we engineered HPV16 E7 coding sequence (wild type or mutagenized sequence, E7GGG) as fusions to -1,3-1,4 ...
Massa, S., Muller, A., Venuti, A., Brandi, R., Mett, V., Franconi, R., Yusibov, V.   +6 more
core   +1 more source