Results 51 to 60 of about 2,254,901 (137)

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

MedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem, Atif Ali, Wajid Ali, Yuying Cheng, Zhibin Yan, Chaoyi Xia, Chenguang Liu, Caiyun Fu, Yiren Hu, Xi Wang   +9 more
wiley   +1 more source

INSL3 Expression in Leydig Cells is a Biomarker for Immunocastration in Boars: Transcriptional Evidence

Andrology, Volume 14, Issue 3, Page 782-795, March 2026.
ABSTRACT Background Study aimed to obtain insights into physiological responses to immunocastration in pubertal boars by evaluating effects of alternative vaccination protocols and identifying a reliable immunocastration biomarker. Objectives It was hypothesized that the timing of gonadotropin‐releasing hormone (GnRH) suppression by immunocastration ...
Nina Batorek Lukač, Martin Škrlep, Klavdija Poklukar, Petra Ferjan, Volker Stefanski, Gregor Fazarinc, Milka Vrecl   +6 more
wiley   +1 more source

Sex‐Specific Factors Influencing HIV Infection

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley   +1 more source

Primary and booster immune responses to SA14-14-2 Japanese encephalitis vaccine in Korean infants

, 1999
Attenuated SA14-14-2 Japanese encephalitis (JE) vaccine has been administered safely and effectively to more than 100 million children in China since 1988 and recently, licensure of the vaccine in Korea has been sought.
박민수
core   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes

Advanced Therapeutics, Volume 9, Issue 2, February 2026.
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava, Lydia Herrmann, Eden Ozkan, Abhiram Kunamneni, Vinamra Swaroop, Geetika Nehra, Rohit Srivastava, Pratima Tripathi, Ken Inoki, Julie E. Goodwin   +9 more
wiley   +1 more source

Bilateral laparoscopic ovariectomy in Dexter heifers under general anaesthesia: A description of two cases

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract This article presents two clinical cases of bilateral laparoscopic ovariectomy in Dexter heifers used as leisure animals to eliminate problematic sexual behaviour. Initial standing flank laparoscopy in one heifer failed due to anatomical limitations.
Cuevas‐Ramos Gabriel, Susan Brix Kronborg, Hanne Gervi Pedersen, Stine Jacobsen   +3 more
wiley   +1 more source

Randomized, Controlled Trial of the Long Term Safety, Immunogenicity and Efficacy of RTS,S/AS02(D) Malaria Vaccine in Infants Living in a Malaria-Endemic Region. [PDF]

, 2013
The RTS,S/AS malaria candidate vaccine is being developed with the intent to be delivered, if approved, through the Expanded Programme on Immunization (EPI) of the World Health Organization.
Machera, Francisca, Abdulla, Salim, Tanner, M., Schellenberg David, Vekemans, J., Richard Kamata, Kamata, Richard, Grace Mwangoka, Kubhoja, S., Leach, Amanda, Villafana Tonya, Dubois Marie-Claude, Sulende Kubhoja, Carter, T, Carter Terrell, Villafana, T, Dubois, M-C, Salim Nahya, Mshinda, H, Dubois, Marie-Claude, Leach, A, Joe Cohen, Salim, N, Kubhoja, Sulende, Vekemans Johan, Salim Abdulla, Mwangoka, G, Carter, T., Juma, O., Mohammed, A., Marcel Tanner, Marie-Claude Dubois, Mshinda Hassan, Marc Lievens, Aebi, Thomas, Kamata, R., Nahya Salim, Ballou, W Ripley, Machera, F., Leach, A., Lievens, Marc, Mohammed Ali, Leach Amanda, Ballou, W. R., W Ripley Ballou, Abdulla, S, Amanda Leach, Kubhoja Sulende, Cohen Joe, Ali Mohammed, Mwangoka Grace, Lievens Marc, Salim, N., Cohen, J., Hassan Mshinda, Abdulla, S., Mohammed, A, Aebi, T, Shomari, M, Mwangoka, G., Schellenberg, D, Cohen, Joe, Schellenberg, D., Machera Francisca, Tanner Marcel, Abdulla Salim, Tanner, M, Carter, Terrell, Juma, Omar, Ballou W Ripley, Omar Juma, Machera, F, Shomari, Mwanajaa, Aebi, T., Schellenberg, David, Mwanajaa Shomari, Lievens, M, Cohen, J, Thomas Aebi, Lievens, M., Juma Omar, Vekemans, J, Juma, O, Vekemans, Johan, Mshinda, Hassan, Tanner, Marcel, Shomari Mwanajaa, Mwangoka, Grace, David Schellenberg, Francisca Machera, Villafana, T., Shomari, M., Mshinda, H., Terrell Carter, Salim, Nahya, Mohammed, Ali, Dubois, M. C., Ballou, WR, Tonya Villafana, Kamata Richard, Kubhoja, S, Aebi Thomas, Johan Vekemans, Kamata, R, Villafana, Tonya   +104 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Actividad inmunopotenciadora de proteoliposomas de muy pequeño tamaño como componente activo de una vacuna peptídica para la terapia del cáncer de próstata

Correo Científico Médico, 2012
Antecedentes: las proteoliposomas de muy pequeño tamaño (VSSP) tienen un efecto adyuvante sobre la respuesta humoral y celular, la activación de células dendríticas y la diferenciación de epitopes T Helper.
Franklin Fuentes Aguilar, Jesús Junco Barranco, Lesvia Calzada Aguilera, Eddy Bover Fuentes, Roberto Basulto Baker, Eulogio Pimentel Vázquez, María Dolores Castro Santana, Yovisleidys Lopez Saes, Niurka Arteaga Moré   +8 more
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