Results 31 to 40 of about 2,254,901 (137)

The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01E on protective efficacy and anti-circumsporozoite protein antibody avidity in African infants [PDF]

, 2015
The malaria vaccine RTS,S induces antibodies against the Plasmodium falciparum circumsporozoite protein (CSP) and the concentration of Immunoglobulin G (IgG) against the repeat region of CSP following vaccination is associated with protection from P ...
Mpina, Maxmilliam, Ajua, Anthony, Abdulla, Salim, Jongert, Erik, Cambron, Pierre, Ockenhouse, Chris F., Agnandji, Selidji Todagbe, Asante, Kwaku Poku, Owusu-Agyei, Seth, Mwangoka, Grace, Kremsner, Peter G., Lell, Bertrand, Mordmüller, Benjamin, Salim, Nahya, Lievens, Marc, Ockenhouse, Chris F, Kremsner, Peter G, Vekemans, Johan, Tanner, Marcel   +18 more
core   +1 more source

Safety and Therapeutic Profile of a GnRH-Based Vaccine Candidate Directed to Prostate Cancer. A 10-Year Follow-Up of Patients Vaccinated With Heberprovac

Frontiers in Oncology, 2019
Heberprovac is a GnRH based vaccine candidate containing 2.4 mg of the GnRHm1-TT peptide as the main active principle; 245 μg of the very small size proteoliposomes adjuvant (VSSP); and 350 μL of Montanide ISA 51 VG oil adjuvant.
Jesús A. Junco, Ranfis Rodríguez, Franklin Fuentes, Idania Baladrón, Maria D. Castro, Lesvia Calzada, Carmen Valenzuela, Eddy Bover, Eulogio Pimentel, Roberto Basulto, Niurka Arteaga, Angel Cid-Arregui, Francisco Sariol, Lourdes González, Liliana Porres-Fong, María Medina, Ayni Rodríguez, A. Hilda Garay, Osvaldo Reyes, Matilde López, Lourdes de Quesada, Allelin Alvarez, Carolina Martínez, Marleny Marrero, Guillermo Molero, Alfredo Guerra, Pedro Rosales, Carlos Capote, Sahily Acosta, Idania Vela, Lina Arzuaga, Ana Campal, Erlán Ruiz, Elier Rubio, Pável Cedeño, María Carmen Sánchez, Pedro Cardoso, Rolando Morán, Yairis Fernández, Magalys Campos, Henio Touduri, Dania Bacardi, Indalecio Feria, Amilcar Ramirez, Karelia Cosme, Pedro López Saura, Maricel Quintana, Verena Muzio, Ricardo Bringas, Marta Ayala, Mario Mendoza, Luis E. Fernández, Adriana Carr, Luis Herrera, Luis Herrera, Gerardo Guillén   +55 more
doaj   +1 more source

The role of Gai in the Gonadotropin-releasing hormone (GnRH) receptor inhibition of cell proliferation [PDF]

, 2011
Includes abstract.Includes bibliographical references (leaves 72-78).The activation of Gonadotropin-releasing hormone receptor (GnRHR) by the GnRH ligand has been shown to mediate antiproliferative effects in extra-pituitary cells and in reproductive ...
Phillips, Pumza Samantha
core   +1 more source

Ligand-induced selective signalling at the gonadotrophin releasing hormone receptor [PDF]

, 2008
Includes abstract.Includes bibliographical references (p. 179-202).The pituitary gonadotrophin releasing hormone (GnRH) receptor regulates reproduction by activation of Gq/11 proteins.
Coetsee, Marla Catherine
core   +1 more source

Brazilian Spotted Fever Prevention through a Nonlethal Capybara Population Control Strategy

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000 - 2018 >600 human deaths) involving synanthropic capybara as host.
Derek Andrew Rosenfield, Gina Polo, Cristiane Schilbach Pizzutto   +2 more
doaj   +1 more source

Congenital hypogonadotropic hypogonadism due to GnRH receptor mutations in three brothers reveal sites affecting conformation and coupling [PDF]

, 2012
Congenital hypogonadotropic hypogonadism (CHH) is characterized by low gonadotropins and failure to progress normally through puberty. Mutations in the gene encoding the GnRH receptor (GNRHR1) result in CHH when present as compound heterozygous or ...
Newton, Claire, Young, Jacques, Claire L Newton, Millar, Robert, Newton, Claire L., Guiochon-Mantel Anne, Young Jacques, Guiochon-Mantel, Anne, Millar, Robert P., Bouligand, Jerome, Newton Claire L., Millar, Robert P, Tello Javier A., Tello, Javier, Anne Guiochon-Mantel, Newton, Claire L, Tello, Javier A., Millar Robert P., Robert P Millar, Jerome Bouligand, Jacques Young, Bouligand Jerome, Tello, Javier A, Javier A Tello   +23 more
core   +2 more sources

Use of anti-gonadotropin-releasing hormone vaccines in African elephants (Loxodonta africana): A review

Bothalia: African Biodiversity & Conservation, 2018
Background: Androgen-related aggressive behaviour and musth cause serious problems in captive African elephant bulls and often lead to human and animal injuries, and damage to property.
Hendrik J. Bertschinger, Imke Lueders
doaj   +1 more source

Administering GonaCon^TM to White-Tailed Deer Via Hand-Injection Versus Syringe-Dart

Human-Wildlife Interactions, 2017
Immunocontraceptive vaccines have shown some promise for fertility control of white-tailed deer (Odocoileus virginianus) in urban and suburban habitats where traditional methods of population control may not be applicable.
Charles S. Evans, Anthony J. DeNicola, John D. Eisemann, Robert J. Warren   +3 more
doaj   +1 more source

Veterinarian attitudes towards immunocontraceptive use in cats

Australian Veterinary Journal, EarlyView.
Background The continuously expanding global cat population poses concerns to public health, native ecosystems and individual animal welfare. These concerns have led to additional management strategies to reduce unowned cat numbers, including the development of feline immunocontraceptives.
E Vartola, S Wills, E Cottingham, CD Marth, N Krekeler   +4 more
wiley   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source