Results 11 to 20 of about 2,254,901 (137)
A synthetic cyclic peptide for promoting antigen presentation and immune activation [PDF]
Cyclic peptides are often used as scaffolds for the multivalent presentation of drug molecules due to their structural stability and constrained conformation. We identified a cyclic deca-peptide incorporating lipoamino acids for delivering T helper and B
Jiahui Zhang +15 more
doaj +2 more sources
Gonadotropin-releasing hormone (GnRH) regulates the reproductive endocrine system in mammals. The GnRH immunocontraception vaccine can aid animal population control and management.
Ai-Mei Chang +4 more
doaj +1 more source
Efficiency of the anti-GnRH vaccine for castration of lambs intended for finishing in pastures
It was aimed to evaluate anti-GnRH vaccine efficiency on productive characteristics, seminal performance, size, and histology of testicles of lambs submitted to immunocastration.
Mariana de Nadai Bonin +9 more
doaj +1 more source
Delivering an Immunocastration Vaccine via a Novel Subcutaneous Implant
Immunocastration relies on the vaccine-mediated stimulation of an immune response to gonadotropin-releasing hormone (GnRH) in order to interrupt spermatogenesis. This approach offers a less painful alternative to traditional castration approaches but the
Andrew K. Curtis +11 more
doaj +1 more source
Immunocastrated female pigs’ social and feeding behaviour [PDF]
This study compared the social and feeding behaviour of immunocastrated female pigs using different immunocastration protocols. We used seventy-two gilts from industrial crossbreeding (Agroceres × Topigs) at 15 weeks of age.
Daniela Regina Klein +8 more
doaj +1 more source
1. As human-wildlife conflicts increase worldwide, novel methods are required for mitigating these conflicts. Fertility control, based on immunocontraceptives, has emerged as an alternative option to lethal methods for managing wildlife.2 ...
G. Massei +8 more
doaj +1 more source
Active immunization against GnRH in ovine (Ovis aries): testicular morphometry, histopathology and endocrine responses in prepubertal ram lambs [PDF]
The main objective of the present research was to assess the effects of an active immunization against GnRH on male reproductive function as an alternative to surgical sterilization evaluating testicular morphometry, histopathological alterations and ...
Gutierrez-Reinoso MA +3 more
doaj +1 more source
The effects of anti-vaccine conspiracy theories on vaccination intentions [PDF]
The current studies investigated the potential impact of anti-vaccine conspiracy beliefs, and exposure to anti-vaccine conspiracy theories, on vaccination intentions. In Study 1, British parents completed a questionnaire measuring beliefs in anti-vaccine
Douglas, Karen M. +8 more
core +1 more source
GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines [PDF]
Breakthrough Breast CancerBackground: Gonadotrophin releasing hormone (GnRH) analogs lower estrogen levels in pre-menopausal breast cancer patients. GnRH receptor (GnRH-R) activation also directly inhibits the growth of certain cells.
Sims Andrew H +27 more
core +2 more sources
The Improvac® vaccine has been shown to improve growth performance, meat quality, and sexual behavior in swine herds in several countries. This study initially investigated the ability of this vaccine to control sex hormones and the development ...
Danh Cong Lai +5 more
doaj +1 more source

