Results 161 to 170 of about 3,164,975 (245)

Efficient One‐Pot Synthesis of Dibenzoxanthenes Using a Vinylimidazolium‐Based Brønsted Acidic Ionic Liquid [VSBIM][Cl]: In Silico Evaluation of Drug‐Likeness, ADMET Properties, PASS Analysis, Antiviral Activity Prediction, and Molecular Docking Studies

open access: yesChemistryOpen, Volume 15, Issue 8, August 2026.
An efficient and solvent‐free sustainable one‐pot protocol is developed for the synthesis of broad range of dibenzoxanthenes using 5 mol% Bronsted acidic ionic liquid [VSBIM][Cl]. The versatility of the methodology was demonstrated by the effective synthesis of 19 dibenzoxanthene derivatives up to 90%–95% yields.
Talamarlla Deepthi, Barnali Maiti
wiley   +1 more source

The Predictive Value of Tenascin‐C, Neopterin and Pro‐Inflammatory Cytokines (IFN‐γ, TNF‐α, IL‐6) in Alcohol Use Disorder Treatment Response

open access: yesAddiction Biology, Volume 31, Issue 8, August 2026.
Thirty patients with AUD undergoing detoxification and 31 healthy controls were evaluated. From baseline to day 7, TNC decreased significantly, accompanied by improvements in depression, anxiety and total symptom scores. Neopterin and cytokine levels remained unchanged.
Guleser Akpinar   +6 more
wiley   +1 more source

Short Inter‐Treatment Interval Treatment With Artificial Liver Support System Reduces 90‐Day Transplant‐Free Mortality in Patients With Hepatitis B Virus–Related Acute‐On‐Chronic Liver Failure: A Retrospective Observational Study

open access: yesArtificial Organs, Volume 50, Issue 8, Page 1145-1152, August 2026.
ALSS short inter‐treatment interval treatment (patients received two ALSS treatments within 48 h) correlates with improved liver function and 90‐day transplant‐free survival of HBV‐ACLF. This result provides a certain theoretical basis for the timing and time interval of ALSS for HBV‐ACLF, enriches the models and contents of ALSS treatment for HBV‐ACLF,
Jingjie Fu   +4 more
wiley   +1 more source

Temporal Association Between COVID‐19 Vaccination and HBsAg Loss in Chronic Hepatitis B Infection: An Interrupted Time Series Analysis

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 4, Page 517-526, August 2026.
In 59,946 chronic hepatitis B patients followed over 23 years, COVID‐19 vaccination rollout was temporally associated with a 56% increase in HBsAg loss rates (peak 1.27 per 100 person‐years in 2022), followed by gradual waning. Negative control outcomes showed no similar pattern, supporting biological specificity. ABSTRACT Background and Aims Hepatitis
Jonggi Choi   +6 more
wiley   +1 more source

Updated Burden and Long‐Term Projections of Chronic Hepatitis B and C in Japan: A Nationwide Markov Modeling Study

open access: yesHepatology Research, Volume 56, Issue 8, Page 1213-1224, August 2026.
ABSTRACT Aim Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections remain major causes of liver‐related morbidity and mortality worldwide. Although Japan has implemented nationwide screening and treatment programs for decades, updated nationwide estimates and long‐term projections are limited.
Junko Tanaka   +4 more
wiley   +1 more source

Preventive Effect of Mineralocorticoid Receptor Antagonists Against Proteinuria Induced by Atezolizumab Plus Bevacizumab Therapy in Hepatocellular Carcinoma: A Multicenter Retrospective Study

open access: yesHepatology Research, Volume 56, Issue 8, Page 1225-1234, August 2026.
Mineralocorticoid receptor antagonists are known to reduce proteinuria in chronic kidney disease, but their effectiveness in preventing bevacizumab‐related proteinuria has not been well established. In the present multi‐institutional retrospective study, we found that these agents significantly delay the onset of moderate or higher grade proteinuria ...
Tomoki Hori   +17 more
wiley   +1 more source

CD49a expression defines a metabolically robust, cytokine‐biased liver NK cell subset in rhesus macaques during lentivirus infection

open access: yesImmunology &Cell Biology, Volume 104, Issue 7, Page 656-666, August 2026.
Liver‐resident NK cells (CD49a+ NK cells) in rhesus macaques display distinct activating receptor and metabolic markers enhanced phenotype compared with hepatic NK cell subsets (CD49a−) in the liver. These cells exhibit heightened cytokine polyfunctionality with restrained cytotoxic responses upon mitogen stimulation in comparison with CD49a− NK cell ...
Andrew Hudson   +4 more
wiley   +1 more source

Differing Epidemiology of Chronic Hepatitis C Infection, Treatment, and Outcomes Among Migrants and Australian‐Born Patients

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 8, August 2026.
ABSTRACT The burden of hepatitis C virus (HCV) infection often falls disproportionately on migrant populations within high‐income countries. Differences in health literacy, language, comorbidities, and HCV genotype may influence HCV natural history. 3537 persons including 652 migrants treated for HCV infection with direct‐acting antiviral (DAA) (2016 ...
Belaynew W. Taye   +17 more
wiley   +1 more source

Trends in Hepatitis B, Hepatitis C, and HIV Seroprevalence in the Netherlands: Insights From Two Decades of Nationwide PIENTER Serosurveys

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 8, August 2026.
ABSTRACT Hepatitis B (HBV), hepatitis C (HCV), and HIV remain public health challenges despite effective treatments and preventive options. Infections are often asymptomatic, leading to undiagnosed cases, onward transmission, and preventable morbidity and mortality.
Christine G. J. I. van Straten   +7 more
wiley   +1 more source

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