Results 71 to 80 of about 3,164,975 (245)

Hepatites pós-transfusionais na cidade de Campinas, SP, Brasil: II. Presença dos anticorpos anti-HBc e anti-HCV em candidatos a doadores de sangue e ocorrência de hepatites pós-transfusionais pelo vírus C nos receptores de sangue ou derivados Post-transfusional hepatitis in the city of Campinas, SP, Brazil: II- Presence of anti-HBc and anti-HCV antibodies in blood donors and occurrence of post-transfusional hepatitis C virus in recipients of blood or derivates

Revista do Instituto de Medicina Tropical de São Paulo, 1993
Pesquisamos os anticorpos anti-HBc e anti-HCV em amostras de soros provenientes de 799 candidatos a doadores, que tiveram suas unidades de sangue ou derivados transfundidas a 111 receptores. O anti-HBc e o anti-HCV foram reagentes, em respectivamente 9 e
Fernando Lopes Gonçales Júnior, Rogério de Jesus Pedro, Luiz Jacintho da Silva, Raquel Silveira Bello Stucchi Boccato, Neiva Sellan Lopes Gonçales   +4 more
doaj   +1 more source

Current approaches for developing new anti-HCV agents and analyses of HCV replication using anti-HCV agents

Uirusu, 2005
Currently, patients with hepatitis C virus (HCV) are mainly treated with interferon alone or in combination with ribavirin. However, because the virus is not eliminated from approximately one half of the patients by this treatment, alternative approaches to the treatment of HCV infection are needed.
WATASHI, Koichi, SHIMOTOHNO, Kunitada
openaire   +3 more sources

Nivolumab and anti-HCV activity, a case report

Acta Clinica Belgica, 2020
Exhaustion of antigen-specific T-cells in order to escape immune destruction is frequently seen in chronic viral infection and different types of cancer. Blockade of overexpressed negative co-stimulatory pathways, a process known as immune checkpoint modulation, is a promising novel therapy that could improve the treatment of liver diseases with ...
Laura Wuyts, Annelies Janssens, Luisa Vonghia, Peter Michielsen, Jo Raskin, Ann Driessen, Stijn Van Hees, Sven Francque, Thomas Vanwolleghem   +8 more
openaire   +3 more sources

Anti-HCV antibodies: A battle for breadth and potency

Antiviral Research
Abstract Potent and broadly neutralizing antibodies (NAbs) are important for clearance of RNA virus infections. However, NAbs generated in response to RNA viruses exhibit diverse profiles of potency and breadth. In this study, we conducted a comparative analysis of NAbs targeting HIV, hepatitis C virus (HCV), SARS-CoV-2, and influenza based on ...
Elham, Jamali, Ahmed Abdul, Quadeer, Nicodemus, Tedla, Matthew R, McKay, Andrew, Lloyd, Melanie R, Walker, Rowena A, Bull   +6 more
openaire   +2 more sources

Prevalence of active HCV infection among the blood donors of Khyber Pakhtunkwa and FATA region of Pakistan and evaluation of the screening tests for anti-HCV

Virology Journal, 2011
Hepatitis C is a fatal liver disease caused by the hepatitis C virus. In this study, blood donors, from various districts of the KPK province and the federally administered tribal area (FATA) of Pakistan were tested for anti-HCV antibodies and HCV RNA by
N. Khan, Ijaz Ali, N. Ahmad, A. Iqbal, Latif U Rehman, I. Munir, M. Rehman, Sanaullah Khan, Sajid Ali, Lubna Siddique, Z. Swati   +10 more
semanticscholar   +1 more source

A descriptive case series of hepatotoxicity associated with CFTR modulators and possible relevance of pharmacogenetic polymorphisms in cystic fibrosis patients

British Journal of Clinical Pharmacology, EarlyView.
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are widely used in patients with cystic fibrosis and significantly improve respiratory function and quality of life. However, their effectiveness may be limited by liver damage, which sometimes leads to treatment discontinuation, and the mechanisms underlying this remain poorly ...
Clara Laffitte Redondo, Venceslas Bourdin, Abd El Kader Ait Tayeb, Sihem Benaboud, Inès Martins, Caroline Joyau, Myriam Benhamida, Isabelle Sermet‐Gaudelus, Clémence Martin, Pierre Régis Burgel, Céline Verstuyft, Laurent Chouchana, Estelle Ayme‐Dietrich   +12 more
wiley   +1 more source

Treatment initiation rates of patients with positive anti-hepatitis C virus results in tertiary hospitals in Turkey

Journal of Infection in Developing Countries
Introduction: The aim of this national, multicenter, cross-sectional, retrospective chart review study was to determine the proportion of patients in Turkey who received hepatitis C virus (HCV) treatment after receiving positive anti-HCV results during ...
Mustafa K Çelen, Buket Ertürk Şengel, Şafak Kaya, Neşe Demirtürk, Alpay Azap, Hüsnü Pullukçu, Esma Eroğlu, Figen Yıldırım, Hüseyin Ş Barut, Esra Zerdali, Ayşe Sağmak Tartar, Ayşe Ö Mete, Ahmet M Şahin, Bedia Mutay Suntur, Nagehan D Sarı, Emel Yılmaz, Aslıhan Candevir, Funda Şimşek, Dilara İnan, Sıla Akhan, Ali Asan, Özgür Günal, Onur Ural, Mehmet Parlak, Mehmet Çabalak, Selçuk Nazik, Kenan Hızel, Sami Kınıklı, Zehra Beştepe Dursun, Ayşe Batırel, Çiğdem Mermutluoğlu   +30 more
doaj   +1 more source

Evaluation of biochemical, hematological, RIBA and PCR assays in predicting viremia in anti-HCV positive patients

Journal of Infection in Developing Countries, 2019
Introduction: The detection of HCV-RNA by PCR assays is considered to be the gold standard for confirming the presence of HCV viremia. However, high costs, long and laborious procedures limit their widespread usage.
Mumtaz Cem Sirin, Buket Cicioglu Aridogan, Emel Sesli Cetin, Fevziye Burcu Sirin   +3 more
doaj   +1 more source

[Anti-HCV seropositivity in dialysis patients].

Revista de saude publica, 2006
Estudo transversal para verificar a prevalência de anticorpos contra hepatite em pacientes dialisados e fatores associados. Foi realizada revisão de prontuários de todos os pacientes dialisados (n=1.261) de Porto Alegre, RS, de agosto a dezembro de 2003. Os testes estatísticos aplicados foram o qui-quadrado e o teste de tendência linear.
Gomes, Marcia, Gigante, Luciana Petrucci, Gomes, Jane, Boschetti, Jaqueline, Carvalho, Glayds   +4 more
openaire   +2 more sources

Delayed anti-HCV antibody response in HIV-positive men acutely infected with HCV

AIDS (London), 2009
Objective:An epidemic of acute hepatitis C virus (HCV) infection among HIV-positive men who have sex with men is occurring in urban centers in Western Europe and the United States.
E. Thomson, E. Nastouli, J. Main, P. Karayiannis, J. Eliahoo, D. Muir, M. Mcclure   +6 more
semanticscholar   +1 more source