Results 121 to 130 of about 317,060 (305)
Health Impacts of Traditional Medicines and Bio-prospecting: A World Scenario Accentuating Bhutan's Perspective [PDF]
Life without natural products is unimaginable. It has provided mankind with oxygen, water, fire, food, clothing, shelter and medicine. Its public health impact is considerably high, especially of traditional medicines and nature-based modern drugs.
Wangchuk, Phurpa
core
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang +13 more
wiley +1 more source
Role of darunavir in the management of HIV infection
R Monica Lascar, Paul BennThe Mortimer Market Centre, Camden PCT, London WC1E 6JBAbstract: There is an ongoing need for potent antiretroviral therapies to deal with the increasing pool of treatment-experienced patients with multiple drug resistance.
R Monica Lascar, Paul Benn
doaj
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu +6 more
wiley +1 more source
Avaliação da aderência aos anti-retrovirais em pacientes com infecção pelo HIV/Aids
OBJETIVOS: Avaliar a aderência aos anti-retrovirais e os principais fatores preditivos e os motivos para a má-aderência. MÉTODOS: Para avaliar a aderência aos medicamentos, realizou-se um estudo em uma amostra aleatória de 120 pacientes com infecção por ...
Luiz Lignani Júnior +2 more
doaj
JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni +6 more
wiley +1 more source
A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform
Randomized PEG (rPEG), a conceptually new PEG alternative, is combined with poly(2‐phenyl‐2‐oxazine) (PPheOzi) to establish an rPEG‐b‐PPheOzi‐b‐rPEG micellar drug delivery platform. The PPheOzi block enables high drug loadings, while competitive ELISA reveals a drastic reduction in anti‐PEG antibody affinity of rPEG in comparison to PEG.
Julian Schmidt +6 more
wiley +1 more source
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan +4 more
wiley +1 more source

