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Functional Roles of Azoles Motif in Anti-HIV Agents
Current Medicinal Chemistry, 2011Currently, there has been considerable interest in the discovery of original molecules with broad-spectrum anti-HIV activity and favourable pharmacokinetic profiles, to be used as an alternative to the approved anti-HIV/AIDS drugs, should they fail as therapeutics.
Dongyue Li +4 more
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Transport, metabolism and elimination mechanisms of anti-HIV agents
Advanced Drug Delivery Reviews, 1999Currently available anti-HIV drugs can be classified into three categories: nucleoside analogue reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, and protease inhibitors. Knowledge of these anti-HIV drugs in various physiological or pharmacokinetic compartments is essential for design and development of drug delivery ...
William K. Chan, Xiaoling Li
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Sulfur Metabolism in AIDS: Cystamine as an Anti-HIV Agent
AIDS Research and Human Retroviruses, 2009Numerous reports have documented disturbances of sulfur metabolism in AIDS patients. There is a generalized loss of sulfur from the body, measured as cysteine and glutathione. The enzyme, cystathionase, has been shown to be greatly decreased in the liver of AIDS patients.
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Current Status of Anti-HIV Agents
Current Medicinal Chemistry -Anti-Infective Agents, 2005V. Tandon, R. Chhor
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Evaluation of Candidate Anti-HIV Agents in vitro
1990Significant progress has been made in the development of anti-HIV therapies for patients with AIDS and other HIV-related illnesses [1-4]. Because of major advances in our understanding of the HIV-1 replicative cycle and identification of potential targets for anti-retroviral therapy, many newer agents are now undergoing preclinical and clinical drug ...
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New acquisitions in the development of anti-HIV agents
Antiviral Research, 1989openaire +3 more sources
Predictive QSAR analysis of anti-HIV agents
Drugs of the Future, 2000V. Nair, T. Mickle
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