Results 31 to 40 of about 2,671,914 (293)

Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]

, 1989
Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Gekeler, V., Müller, C. A., Engler-Blum, G., Steiert, I., Weiss, Elisabeth H., Schmidt, H.   +5 more
core   +1 more source

Heart transplantation and anti‐HLA antibodY: myocardial dysfunction and prognosis ‐ HeartLAy study

ESC Heart Failure, 2023
Aims The presence of anti‐human leucocyte antigen (HLA) antibodies has been implicated in a higher incidence of complications as well as mortality rate in heart transplantation.
Carlotta Sciaccaluga, Benedetta Maria Natali, Francesca Maria Righini, Carlotta Sorini Dini, Federico Landra, Giulia Elena Mandoli, Nicolò Sisti, Daniele Menci, Antonio D'Errico, Flavio D'Ascenzi, Marta Focardi, Sonia Bernazzali, Massimo Maccherini, Serafina Valente, Matteo Cameli   +14 more
doaj   +1 more source

Humanization and characterization of the anti-HLA-DR antibody 1D10 [PDF]

International Journal of Cancer, 2001
1D10 is a previously described antibody that binds to cells from a majority of B-cell malignancies. The current studies were designed to further evaluate the antigen specificity of 1D10 and its potential as an immunotherapeutic agent. Studies with transfectants and immunoprecipitation demonstrated that 1D10 recognizes some, but not all, of the human ...
S A, Kostelny, B K, Link, J Y, Tso, M, Vasquez, B H, Jorgensen, H, Wang, W C, Hall, G J, Weiner   +7 more
openaire   +2 more sources

Anti-HLA antibodies in transplant patients.

, 2018
Anti-HLA antibodies were analyzed in kidney transplant patients before transplantation and at the end of follow-up by LABScreen® assays using Luminex xMAP technology.
Rebeca Alonso-Arias (5089019), Alejandra García-Torre (5089028), María Luisa Suárez-Fernández (5089022), Pablo Martínez-Camblor (295223), Marco Antonio Moro-García (5089013), Minerva Rodríguez (5089010), Marta Elena Álvarez-Argüelles (276222), María Iglesias-Escudero (5089016), Raquel Marcos-Fernández (5089025)   +8 more
core   +1 more source

Prevalence of pre-transplant anti-HLA antibodies and their impact on outcomes in lung transplant recipients

BMC Pulmonary Medicine, 2018
Background Previous studies have suggested that antibodies against human leukocyte antigen (HLA) are associated with worse outcomes in lung transplantation.
Ji Eun Park, Chi Young Kim, Moo Suk Park, Joo Han Song, Young Sam Kim, Jin Gu Lee, Hyo Chae Paik, Song Yee Kim   +7 more
doaj   +1 more source

Anti-HLA I antibodies induce VEGF production by endothelial cells, which increases proliferation and paracellular permeability

, 2009
Anti-human leukocyte antigen class I (HLA I) antibodies were shown to activate several protein kinases in endothelial cells (ECs), which induces proliferation and cell survival.
Ligeti, Nathalie, Bieri, Jürg, Bieri, Michael, Mohacsi, Paul, Farkas, Anikò, Oroszlan, Melinda, Mohacsi P, Oroszlan M, Bieri J, Bieri M, Ligeti N, Farkas A, Nathalie Ligeti, Jürg Bieri, Melinda Oroszlan, Paul Mohacsi, Michael Bieri, Anikò Farkas   +17 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

HLA-DRB1*0404 is strongly associated with high titers of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis.

, 2008
International audienceOBJECTIVE: To test whether the presence of RA associated HLA-DRB1*0101, HLA-DRB1*0401 and HLA-DRB1*0404 alleles individually influences anti-cyclic citrullinated peptide antibodies (anti-CCP) production.
Charpin, C., Roudier, C., Lambert, N., Auger, I., Rak, J., Balandraud, N., Roudier, J., Guis, Sandrine, Toussirot, E., Martin, M., Reviron, D.   +10 more
core   +6 more sources

Maternal HLA Ib Polymorphisms in Pregnancy Allo-Immunization

Frontiers in Immunology, 2021
During pregnancy the formation of alloreactive anti-human leukocyte antigen (HLA) antibodies are a major cause of acute rejection in organ transplantation and of adverse effects in blood transfusion.
Gry Persson, Christophe Picard, Christophe Picard, Gregory Marin, Cecilie Isgaard, Cecilie Isgaard, Christina Seefeldt Stæhr, Christina Seefeldt Stæhr, Nicolas Molinari, Jacques Chiaroni, Morten Lebech, Thomas Vauvert F. Hviid, Thomas Vauvert F. Hviid, Julie Di Cristofaro   +13 more
doaj   +1 more source

Antibodies to the Mr 64,000 (64K) protein in islet cell antibody positive non-diabetic individuals indicate high risk for impaired Beta-cell function [PDF]

, 1992
A prospective study of a normal childhood population identified 44 islet cell antibody positive individuals. These subjects were typed for HLA DR and DQ alleles and investigated for the presence of antibodies to the Mr 64,000 (64K) islet cell antigen ...
Glück, Michael, Bretzel, Reinhard G., Federlin, Konrad, Seißler, Jochen, Hering, Bernhard J., Böhm, Bernhard Otto, Yassin, Nuha, Scherbaum, Werner A., Richter, Wiltrud   +8 more
core   +1 more source