Results 41 to 50 of about 2,671,914 (293)

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

HLA class II antigens in Croatian patients with pemphigus vulgaris and their correlation with anti-desmoglein antibodies

Frontiers in Immunology, 2023
Pemphigus vulgaris (PV) is an acquired autoimmune blistering disease characterized by the production of autoantibodies targeting desmosomal cadherins, primarily desmoglein 1 and desmoglein 3, leading to acantholysis. The etiology of PV is multifactorial,
Ines Lakoš Jukić, Ines Lakoš Jukić, Mislav Mokos, Branka Marinović, Branka Marinović   +4 more
doaj   +1 more source

Effect Modification of Cigarette Smoking on the Relationship Between Posttraumatic Stress Disorder, Other Mental Health Conditions, and Rheumatoid Arthritis Risk: A Large Case‐Control Study in US Veterans

Arthritis Care &Research, EarlyView.
Objective We examined associations of posttraumatic stress disorder (PTSD) and other mental health disorders (OMH) with rheumatoid arthritis (RA), accounting for effects of smoking. Methods We conducted a matched case‐control study, identifying incident RA cases and controls using national Veterans Health Administration data (2006–2019).
Kelsey Coziahr, Harlan Sayles, Tate M. Johnson, Joshua F. Baker, Punyasha Roul, Grant W. Cannon, Gary A. Kunkel, Katherine D. Wysham, Gail S. Kerr, Amir A. Razmjou, Isaac Smith, Jennifer L. Barton, Maria I. Danila, Jonathan S. Richards, Bryant R. England, Ted R. Mikuls   +15 more
wiley   +1 more source

Intra-operative kinetics of anti-HLA antibody in simultaneous liver-kidney transplantation

Molecular Genetics and Metabolism Reports, 2021
During simultaneous liver-kidney transplantation (SLK) in highly sensitized patients, donor specific anti-human leukocyte antigen antibodies (DSA, HLA) can be present prior to transplant leading to positive crossmatch, yet these recipients have ...
M. Kueht, P. Jindra, H.L. Stevenson, T.N. Galvan, B. Murthy, J. Goss, J. Anton, R. Abbas, M.F. Cusick   +8 more
doaj   +1 more source

Correlation between maternal and fetal anti-HLA class I and class II antibodies.

, 2013
The panel reactivity of maternal anti-HLA antibodies is associated with that of fetal anti-HLA antibodies (for anti-HLA class I antibodies: r = 0.578 ...
Vanessa Topping (356439), JoonHo Lee (344749), Chong Jai Kim (212418), Jung-Sun Kim (356438), Juan Pedro Kusanovic (270688), Sonia S. Hassan (344754), Roberto Romero (19224), Bo Hyun Yoon (317495), Yi Xu (131145), Wonsuk Yoo (190903), Tinnakorn Chaiworapongsa (344752)   +10 more
core   +1 more source

Frequency of HLA antibodies in South India [PDF]

, 1993
Sera from 4088 pregnant women (649 antenatal bleeding and 3439 post-partum bleeding) living in Madurai, were collected and screened for anti-HLA. A, B and DR antibodies. 696 of them were screened for anti-HLA DR antibodies.
Mahendran, V., Manuel, May, Balakrishnan, K., Shankar Kumar, U., Indra Raja, V., Brahmajothi, V., Pitchappan, R. M., Amutha, S., Shantha Kumari, R., Sashidhar, M., SamalRaj   +10 more
core   +1 more source

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Pathologic findings in lung allografts with anti-HLA antibodies [PDF]

The Journal of Heart and Lung Transplantation, 2013
Despite data indicating a positive correlation between donor-specific anti-HLA antibodies (DSAs) and early development of bronchiolitis obliterans syndrome (BOS) in lung allografts, the role of an antibody-mediated process in acute and chronic lung allograft rejection has not been elucidated. In this study we evaluated pathologic features of transplant
Matthew M, DeNicola, Sam S, Weigt, John A, Belperio, Elaine F, Reed, David J, Ross, W Dean, Wallace   +5 more
openaire   +2 more sources

Experience of using polymethyl methacrylate membranes for anti-HLA antibodies’ elimination by hemodialysis in renal transplant recipients

Трансплантология (Москва), 2019
Introduction. In recipients with pre-existing sensitization with incompatible antigens of the main histocompatibility complex, the kidney graft survival after retransplantations directly depends on the level of anti-HLA antibodies.
E. I. Pervakova, V. V. Vasilets, O. N. Rzhevskaya, N. V. Borovkova, A. V. Pinchuk   +4 more
doaj   +1 more source