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Pharmaceutics, 2022 Chronic inflammation plays a side effect on tissue regeneration, greatly inhibiting the repair or regeneration of tissues. Conventional local delivery of anti-inflammation drugs through physical encapsulation into carriers face the challenges of ...
Jingjing Ye +7 more
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BMEMatOsteoarthritis (OA) is a chronic and degenerative disease with limited clinical options for effective suppression. Recently, significant endeavors have been explored to reveal its pathogenesis and develop treatments against OA. Hydrogels, designed with a
Xuwei Jiang +6 more
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Genetic Engineering Bacillus thuringiensis Enable Melanin Biosynthesis for Anti‐Tumor and Anti‐Inflammation [PDF]
Advanced ScienceCollaboration between cancer treatment and inflammation management has emerged as an integral facet of comprehensive cancer care. Nevertheless, the development of interventions concurrently targeting both inflammation and cancer has encountered ...
Meng Chen +12 more
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Effect of Cell Generations on t-BHP-induced Oxidative Stress Model of Caco-2 Cells
Shipin gongye ke-ji, 2023 Objective: To investigate the effects of cell passage number on the establishment of an oxidative stress model in human colon adenocarcinoma cells (Caco-2) caused by tert-butyl hydroperoxide (t-BHP).
Jun NI +6 more
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Acta Pharmaceutica Sinica B, 2022 Phosphodiesterase-4 (PDE4) functions as a catalyzing enzyme targeting hydrolyzation of intracellular cyclic adenosine monophosphate (cAMP) and inhibition of PDE4 has been proven to be a competitive strategy for dermatological and pulmonary inflammation ...
Heng Li +11 more
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Frontiers in Pharmacology, 2023 Chlorogenic acid is a bioactive compound ubiquitously present in the natural realm, lauded for its salient anti-inflammatory and antioxidant attributes. It executes its anti-inflammatory function by moderating the synthesis and secretion of inflammatory ...
Jianhuan Huang +4 more
semanticscholar +1 more source
Bmal1 Regulates Macrophage Polarize Through Glycolytic Pathway in Alcoholic Liver Disease
Frontiers in Pharmacology, 2021 Hepatic macrophages play a critical role in inflammation caused by alcohol feeding. During this process, variation of macrophage phenotypes triggers inflammatory responses in a variety of ways. Moreover, there is increasing evidence that Brain and Muscle
Yiwen Zhou +20 more
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Untargeted Metabolomics Identifies a Novel Panel of Markers for Autologous Blood Transfusion
Metabolites, 2022 Untargeted metabolomics was used to analyze serum and urine samples for biomarkers of autologous blood transfusion (ABT). Red blood cell concentrates from donated blood were stored for 35–36 days prior to reinfusion into the donors.
Amna Al-Nesf +12 more
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International Journal of Nanomedicine, 2023 Introduction Ginger extract (GE) has sparked great interest due to its numerous biological benefits. However, it suffers from limited skin permeability, which challenges its transdermal application.
Abeer S. Hassan +3 more
semanticscholar +1 more source
Vaccarin alleviates cisplatin-induced acute kidney injury via decreasing NOX4-derived ROS
Heliyon, 2023 Cisplatin is a chemotherapeutant widely used in treating solid tumors, with the common side effect of acute kidney injury (AKI). Developing effective useful agent for preventing or treating cisplatin-induced AKI is of great importance.
Tingni Wu +19 more
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