Results 21 to 30 of about 4,687,299 (337)

20-hydroxyecdysone dilates muscle arterioles in a nitric oxide-dependent, estrogen ER-β receptor-independent manner

open access: yesPhytomedicine Plus, 2021
Background: 20-hydroxyecdysone is an ecdysteroid which is abundant in plants and insects and has anabolic potentials in mammals. It was recently shown to have affinity for estrogen ER-β receptor, which could potentially make it vasodilatory.
Nelson N Orie   +9 more
doaj   +1 more source

Exosomes secreted by FNDC5-BMMSCs protect myocardial infarction by anti-inflammation and macrophage polarization via NF-κB signaling pathway and Nrf2/HO-1 axis

open access: yesStem cell research & therapeutics, 2021
Background Exosomes are considered a substitute for stem cell-based therapy for myocardial infarction (MI). FNDC5, a transmembrane protein located in the cytoplasm, plays a crucial role in inflammation diseases and MI repair.
Hongjuan Ning   +7 more
semanticscholar   +1 more source

The Role of CCL3 in the Pathogenesis of Rheumatoid Arthritis

open access: yesRheumatology and Therapy, 2023
Rheumatoid arthritis (RA) is a chronic autoimmune disease of unexplained causes. Its pathological features include synovial tissue hyperplasia, inflammatory cell infiltration in joint cavity fluid, cartilage bone destruction, and joint deformation.
Ying-Li Yang   +6 more
doaj   +1 more source

The Screening of Therapeutic Peptides for Anti-Inflammation through Phage Display Technology

open access: yesInternational Journal of Molecular Sciences, 2022
For the treatment of inflammatory illnesses such as rheumatoid arthritis and carditis, as well as cancer, several anti-inflammatory medications have been created over the years to lower the concentrations of inflammatory mediators in the body.
Kangran Zhang   +3 more
semanticscholar   +1 more source

Caveolin-1 Alleviates Acetaminophen-Induced Fat Accumulation in Non-Alcoholic Fatty Liver Disease by Enhancing Hepatic Antioxidant Ability via Activating AMPK Pathway

open access: yesFrontiers in Pharmacology, 2021
Non-alcoholic fatty liver disease (NAFLD) is an independent risk factor for acute liver injury caused by overuse of acetaminophen (APAP). Caveolin-1 (CAV1), a regulator of hepatic energy metabolism and oxidative stress, was found to have a protective ...
Jiarong Wang   +23 more
doaj   +1 more source

PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis

open access: yesFrontiers in Pharmacology, 2021
Rheumatoid arthritis (RA) is characterized by a tumor-like expansion of the synovium and subsequent destruction of adjacent articular cartilage and bone.
Xiao-Feng Li   +15 more
doaj   +1 more source

Inflammation‐Controlled Anti‐Inflammatory Hydrogels

open access: yesAdvanced Science, 2023
While autoregulative adaptation is a common feature of living tissues, only a few feedback‐controlled adaptive biomaterials are available so far. This paper herein reports a new polymer hydrogel platform designed to release anti‐inflammatory molecules in
Tina Helmecke   +8 more
doaj   +1 more source

Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis [PDF]

open access: yes, 2011
PMCID: PMC3212807This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Damazo, AS   +5 more
core   +3 more sources

Characterization, Antioxidant and Anti-Inflammation Capacities of Fermented Flammulina velutipes Polyphenols

open access: yesMolecules, 2021
This work investigated the preparation, characterization, antioxidant, and anti-inflammation capacities of Flammulina velutipes polyphenols (FVP) and fermented FVP (FFVP).
Sheng Ma, Hongcai Zhang, Jianxiong Xu
semanticscholar   +1 more source

CaM/CaMKII mediates activation and proliferation of hepatic stellate cells regulated by ASIC1a

open access: yesFrontiers in Pharmacology, 2022
The activation of hepatic stellate cells (HSCs) is closely related to hepatic fibrosis and plays a key role in its occurrence and development. In the damaged liver, inhibition of the activation, proliferation, and clearance of HSCs is an important ...
Hui Liu   +30 more
doaj   +1 more source

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