Results 61 to 70 of about 4,687,299 (337)

Biosynthetic ε-poly-L-lysine for the treatment of extensively- and pan-drug-resistant Pseudomonas aeruginosa

npj Antimicrobials and Resistance
Pseudomonas aeruginosa (PA) represents a major cause of antimicrobial resistance-related morbidity and mortality. The recent emergence of highly fatal infections, caused by carbapenem-resistant PA, has called for novel antimicrobial therapies and ...
Darren Shu Jeng Ting, Thet Tun Aung, Venkatesh Mayandi, Mercy Halleluyah Periayah, Eunice Tze Leng Goh, Mugil Muthu, Veluchamy Amutha Barathi, Jodhbir S. Mehta, Donald Tiang Hwee Tan, Rajamani Lakshminarayanan   +9 more
doaj   +1 more source

Systemic sclerosis-associated pulmonary arterial hypertension and pulmonary fibrosis: exploring biomarker discriminators with advanced omics in a Caucasian cohort

Frontiers in Immunology
IntroductionSystemic sclerosis (Scleroderma; SSc) is associated with high morbidity and mortality, particularly in patients with pulmonary arterial hypertension (SSc-PAH) and pulmonary fibrosis (SSc-PF). Effective risk stratification and treatment of SSc
Nada Mohamed-Ali, Vanessa Acquaah, Maneera Al-Jaber, Rikesh Bhatt, Ibrahim Al-Mohannadi, Konduru Seetharama Sastry, Alka Beotra, Daniel Knight, Daniel Knight, Christopher Denton, Voon Ong, Maryam Ali Al-Nesf, Maryam Ali Al-Nesf, David Abraham, Mohammed Al-Maadheed, Mohammed Al-Maadheed, Markella Ponticos, Vidya Mohamed-Ali, Vidya Mohamed-Ali   +18 more
doaj   +1 more source

Polysaccharide Peptide: A promising Anti Inflammation and Anti Oxidant in Atherosclerosis

Majalah Kardiologi Indonesia, 2015
Background : Heart disease is the leading cause of death for both men and women, but heart disease is preventable and controllable. Ganoderma lucidum is widely used as traditional medicine for centuries particularly in China, Japan, and Korea.
Indra Prasetya, Ria Ashriyah, Ira Setyawati, Joko Hermawan, Widyo Mahargo, Yunita Leksono, Titin Andri W., Teuku Heriansyah, Muhammad Aris W., Djanggan Sargowo   +9 more
doaj   +1 more source

Antidiabetic effect of Tibetan medicine Tang-Kang-Fu-San on high-fat diet and streptozotocin-induced type 2 diabetic rats [PDF]

, 2017
The aim of this study was to investigate the antidiabetic effects of a Tibetan medicine, Tang-Kang-Fu-San (TKFS), on experimental type 2 diabetes mellitus (T2DM) rats and to explore its underlying mechanisms.
Duan, Bailu, Gao, Tiexiang, Jin, Jing, Lin, Ling, Mei, Zhinan, Ta, Na, Xiong, Hui, Zhang, Lijun, Zhao, Zhongqiu   +8 more
core   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Transcriptome investigation of anti‐inflammation and immuno‐regulation mechanism of taurochenodeoxycholic acid

BMC Pharmacology and Toxicology, 2021
Background Taurochenodeoxycholic acid (TCDCA) is one of the major active components in bile acid. It was proven to have inhibitory activities on inflammation and also participate in host immuno-regulation.
Lige Bao, Dacheng Hao, Xu Wang, Xiuling He, Wei Mao, Peifeng Li   +5 more
doaj   +1 more source

Anti-inflammatory effects of hunger are transmitted to the periphery via projection-specific AgRP circuits

Cell Reports, 2023
Summary: Caloric restriction has anti-inflammatory effects. However, the coordinated physiological actions that lead to reduced inflammation in a state of caloric deficit (hunger) are largely unknown.
Michelle L. Klima, Kayla A. Kruger, Nitsan Goldstein, Santiago Pulido, Aloysius Y.T. Low, Charles-Antoine Assenmacher, Amber L. Alhadeff, J. Nicholas Betley   +7 more
doaj   +1 more source

The effects of anti-sense interleukin-5 gene transferred by recombinant adeno-associated virus in allergic rats [PDF]

, 2008
The accumulation and infiltration of eosinophils in airways is one of the most important characteristics of asthma, and is mediated partly by secretion of IL-5 from Th2 lymphocytes.
Chao Cao, Daxiong Zeng, Qingfeng Song, Weining Xiong, Xiansheng Liu, Yong Cao, Yongjian Xu   +6 more
core   +1 more source

Autophagy and anti-inflammation ameliorate diabetic neuropathy with Rilmenidine

Acta Cirúrgica Brasileira, 2023
To evaluate the neuroprotective effects of Rilmenidine on diabetic peripheral neuropathy (DPN) in a rat model of diabetes induced by streptozotocin (STZ).STZ (60 mg/kg) was administered to adult Sprague-Dawley rats to induce diabetes. On the 30th day after STZ administration, electromyography (EMG) and motor function tests confirmed the presence of DPN.
Mehmet Burak Yalçın, Ejder Saylav Bora, Adem Çakır, Sabiye Akbulut, Oytun Erbaş   +4 more
openaire   +4 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source