Results 51 to 60 of about 5,688,015 (387)
Metallothionein as an Anti-Inflammatory Mediator [PDF]
Mediators of Inflammation, 2009 The integration of knowledge concerning the regulation of MT, a highly conserved, low molecular weight, cystein-rich metalloprotein, on its proposed functions is necessary to clarify how MT affects cellular processes. MT expression is induced/enhanced in various tissues by a number of physiological mediators.
Masahiko Satoh +3 more
openaire +4 more sources
Anti-inflammatory therapy in atherosclerosis [PDF]
Frontiers in Bioscience, 2020 Cardiovascular disease (CVD) is the leading cause of death. Although once considered merely as a lipid storage disease, studies indicate the role of inflammation in initiation and progression of atherosclerotic CVD, as well as the development of thrombotic complications. Despite significant advances in treatment of atherosclerosis, there still exists a
Lale Tokgozoglu +2 more
openaire +3 more sources
Mediators of Inflammation, 2018 MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level via direct binding to the 3′-untranslated region (UTR) of target mRNAs.
Wenming Hong +4 more
doaj +1 more source
Pro-Inflammatory and Anti-Inflammatory Interleukins in Infectious Diseases: A Comprehensive Review
Tropical Medicine and Infectious DiseaseInterleukins (ILs) are signaling molecules that are crucial in regulating immune responses during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment of immune cells, whereas anti-inflammatory ILs help to suppress ...
A. Al-Qahtani +2 more
semanticscholar +1 more source
Anti-Inflammatory Drugs as Anticancer Agents
International Journal of Molecular Sciences, 2020 Inflammation is strictly associated with cancer and plays a key role in tumor development and progression. Several epidemiological studies have demonstrated that inflammation can predispose to tumors, therefore targeting inflammation and the molecules ...
S. Zappavigna +7 more
semanticscholar +1 more source
Frontiers in Molecular Neuroscience, 2019 The essential roles of microglia in maintaining homeostasis in the healthy brain and contributing to neuropathology are well documented. Emerging evidence suggests that epigenetic modulation regulates microglial behavior in both physiological and ...
Yawei Guo +7 more
doaj +1 more source
Immunomodulatory and Anti-Inflammatory Effects of Fucoidan: A Review
Polymers, 2020 Inflammation is the initial response of the immune system to potentially harmful stimuli (e.g., injury, stress, and infections). The process involves activation of macrophages and neutrophils, which produce mediators, such as nitric oxide (NO ...
E. Apostolova +10 more
semanticscholar +1 more source
Frontiers in Immunology, 2018 Fibroblast-like synoviocytes (FLS) and macrophage-like synoviocytes (MLS) are the two main cellular components of the synovium. It has been widely reported that FLS and MLS play essential roles in the joint pathology of rheumatoid arthritis (RA ...
Jiajie Tu +7 more
doaj +1 more source
The role of atrial natriuretic peptide to attenuate inflammation in a mouse skin wound and individually perfused rat mesenteric microvessels. [PDF]
, 2016 We tested the hypothesis that the anti-inflammatory actions of atrial natriuretic peptide (ANP) result from the modulation of leukocyte adhesion to inflamed endothelium and not solely ANP ligation of endothelial receptors to stabilize endothelial barrier
Adamson, Roger H +5 more
core +2 more sources
Plants as Sources of Anti-Inflammatory Agents
Molecules, 2020 Plants represent the main source of molecules for the development of new drugs, which intensifies the interest of transnational industries in searching for substances obtained from plant sources, especially since the vast majority of species have not yet
C. R. Nunes +7 more
semanticscholar +1 more source