Ginsenoside Rg1 treatment alleviates renal fibrosis by inhibiting the NOX4–MAPK pathway in T2DM mice
Diabetic kidney disease (DKD) is a severe complication of type 2 diabetes mellitus (T2DM). However, the pathogenesis of DKD remains unclear, and effective treatment strategies are still lacking. Ginsenoside Rg1 (Rg1) has been reported to improve DKD, but
Pengmin Ji+8 more
doaj +1 more source
Novel antioxidant and anti-inflammatory peptides from the Siamese crocodile (Crocodylus siamensis) hemoglobin hydrolysate [PDF]
Novel antioxidant and anti-inflammatory peptides were isolated from hydrolysates of Siamese crocodile (Crocodylus siamensis) hemoglobin. C. siamensis hemoglobin hydrolysates (CHHs) were obtained by pepsin digestion at different incubation times (2, 4, 6,
Jangpromma, Nisachon+7 more
core +1 more source
Anti-inflammatory diet or anti-inflammatory lifestyle?
Chronic low-grade inflammation is increasingly proving to be one of the main culprits for the onset of numerous pathologies. Until recently, to try to combat this insidious enemy, we mainly resorted to anti-inflammatory diets, but current scientific evidence seems to support the hypothesis that the maximum impact on health could be obtained above all ...
David Mariani, Sabrina Lucchetti
openaire +2 more sources
New insights into the anti-inflammatory mechanisms of glucocorticoids : an emerging role for glucocorticoid-receptor-mediated transactivation [PDF]
Glucocorticoids are anti-inflammatory drugs that are widely used for the treatment of numerous (autoimmune) inflammatory diseases. They exert their actions by binding to the glucocorticoid receptor (GR), a member of the nuclear receptor family of ...
Dejager, Lien+3 more
core +1 more source
The role of a key transcription factor PU.1 in autoimmune diseases
PU.1, a transcription factor member of the E26 transformation-specific family, affects the function of a variety of immune cells in several physiological and pathological conditions.
Yilong Fang+15 more
doaj +1 more source
Impact of Janus Kinase Inhibition with Tofacitinib on Fundamental Processes of Bone Healing [PDF]
Both inflammatory diseases like rheumatoid arthritis (RA) and anti-inflammatory treatment of RA with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs) negatively influence bone metabolism and fracture healing.
Brinkman, Antonia Clara Katharina+10 more
core +1 more source
Anti-inflammatory Effects of Phosphatidylcholine [PDF]
We recently showed that mucus from patients with ulcerative colitis, a chronic inflammatory disorder of the colon, is characterized by a low level of phosphatidylcholine (PC) while clinical studies reveal that therapeutic addition of PC using slow release preparations is beneficial. The positive role of PC in this disease is still elusive.
Treede, Irina+11 more
openaire +4 more sources
Honey anti-inflammatory factor identified [PDF]
Four different brands of honey wound dressings are now on sale internationally as registered medical devices, all made from manuka honey because of its well-established reputation as an antibacterial agent.
Molan, Peter C.
core +1 more source
Anti-inflammatory and wound healing properties of Malaysia tualang honey [PDF]
Inflammation is a biological response and a defence mechanism by the body to remove harmful stimuli followed by the healing process. Healing is a process of skin and other soft tissue repair at the site of injury. However, uncontrolled inflammation could
Devasvaran, Kogilavanee+1 more
core +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source