Results 31 to 40 of about 2,225,971 (290)

Ontogeny of Synovial Macrophages and the Roles of Synovial Macrophages From Different Origins in Arthritis

Frontiers in Immunology, 2019
The ontogeny of macrophages in most organ/tissues in human body has been proven. Due to the limited number and inaccessibility of synovial macrophages (SM), the origin of SM has not been fully illuminated.
Jiajie Tu, Wenming Hong, Wenming Hong, Yawei Guo, Pengying Zhang, Yilong Fang, Xinming Wang, Xinming Wang, Xiaoyun Chen, Shanshan Lu, Wei Wei   +10 more
doaj   +1 more source

The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods [PDF]

, 1964
1. The forms of irritation causing inflammation and pain are reviewed, with reference to the significance of histamine, serotonin and bradykinin and in particular to the interrelationship between inflammation and pain. 2.
Wilhelmi, G.
core   +1 more source

CXCL16/CXCR6 axis drives microglia/macrophages phenotype in physiological conditions and plays a crucial role in glioma [PDF]

, 2018
Microglia are patrolling cells that sense changes in the brain microenvironment and respond acquiring distinct phenotypes that can be either beneficial or detrimental for brain homeostasis.
Antonangeli, Fabrizio, D'Alessandro, Giuseppina, Esposito, Vincenzo, Lepore, Francesca, Limatola, Cristina, Santoro, Antonio, Trettel, Flavia   +6 more
core   +1 more source

N-Arachidonoyl Dopamine Modulates Acute Systemic Inflammation via Nonhematopoietic TRPV1. [PDF]

, 2017
N-Arachidonoyl dopamine (NADA) is an endogenous lipid that potently activates the transient receptor potential vanilloid 1 (TRPV1), which mediates pain and thermosensation. NADA is also an agonist of cannabinoid receptors 1 and 2.
Hellman, Judith, Lawton, Samira K, Prakash, Arun, Schumacher, Mark, Tran, Alphonso, Wilhelmsen, Kevin, Wong, Erika, Xu, Fengyun   +7 more
core   +2 more sources

MicroRNAs in Microglia: How do MicroRNAs Affect Activation, Inflammation, Polarization of Microglia and Mediate the Interaction Between Microglia and Glioma?

Frontiers in Molecular Neuroscience, 2019
The essential roles of microglia in maintaining homeostasis in the healthy brain and contributing to neuropathology are well documented. Emerging evidence suggests that epigenetic modulation regulates microglial behavior in both physiological and ...
Yawei Guo, Wenming Hong, Wenming Hong, Xinming Wang, Pengying Zhang, Heinrich Körner, Jiajie Tu, Wei Wei   +7 more
doaj   +1 more source

Ginsenoside Rg1 alleviates Aβ deposition by inhibiting NADPH oxidase 2 activation in APP/PS1 mice

Journal of Ginseng Research, 2021
Background: Ginsenoside Rg1 (Rg1), an active ingredient in ginseng, may be a potential agent for the treatment of Alzheimer’s disease (AD). However, the protective effect of Rg1 on neurodegeneration in AD and its mechanism of action are still ...
Han Zhang, Yong Su, Zhenghao Sun, Ming Chen, Yuli Han, Yan Li, Xianan Dong, Shixin Ding, Zhirui Fang, Weiping Li, Weizu Li   +10 more
doaj   +1 more source

Ontology and Function of Fibroblast-Like and Macrophage-Like Synoviocytes: How Do They Talk to Each Other and Can They Be Targeted for Rheumatoid Arthritis Therapy?

Frontiers in Immunology, 2018
Fibroblast-like synoviocytes (FLS) and macrophage-like synoviocytes (MLS) are the two main cellular components of the synovium. It has been widely reported that FLS and MLS play essential roles in the joint pathology of rheumatoid arthritis (RA ...
Jiajie Tu, Wenming Hong, Wenming Hong, Pengying Zhang, Xinming Wang, Xinming Wang, Heinrich Körner, Wei Wei   +7 more
doaj   +1 more source

Dairy products and inflammation: a review of the clinical evidence [PDF]

, 2015
Inflammation is a major biological process regulating the interaction between organisms and the environment, including the diet. Because of the increase in chronic inflammatory diseases, and in light of the immune-regulatory properties of breastfeeding ...
Bordoni, Allessandra, Dansesi, Francesca, Dardevet, Dominique, Dupont, Didier, Fernandez, Aida S., Gille, Doreen, Nunes dos Santos, Claudia, Pinto, Paula, Re, Roberta, Remond, Didier, SHAHAR, DANIT, Vergères, Guy   +11 more
core   +4 more sources

The Role of CTHRC1 in Regulation of Multiple Signaling and Tumor Progression and Metastasis

Mediators of Inflammation, 2020
Collagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. CTHRC1 expresses mainly in adventitial fibroblasts and neointimal smooth muscle cells of balloon-injured vessels and promotes cell migration and tissue ...
Dan Mei, Yue Zhu, Lingling Zhang, Wei Wei   +3 more
doaj   +1 more source

Long non-coding RNAs: Potential therapeutic targets for epilepsy

Frontiers in Neuroscience, 2022
Epilepsy is a common and disastrous neurological disorder characterized by abnormal firing of neurons in the brain, affecting about 70 million people worldwide.
Sen Liu, Sen Liu, Sen Liu, Min Fan, Min Fan, Min Fan, Meng-Die Ma, Meng-Die Ma, Meng-Die Ma, Jin-Fang Ge, Jin-Fang Ge, Jin-Fang Ge, Fei-Hu Chen, Fei-Hu Chen, Fei-Hu Chen   +14 more
doaj   +1 more source