Results 31 to 40 of about 4,511,051 (310)

Ontology and Function of Fibroblast-Like and Macrophage-Like Synoviocytes: How Do They Talk to Each Other and Can They Be Targeted for Rheumatoid Arthritis Therapy?

Frontiers in Immunology, 2018
Fibroblast-like synoviocytes (FLS) and macrophage-like synoviocytes (MLS) are the two main cellular components of the synovium. It has been widely reported that FLS and MLS play essential roles in the joint pathology of rheumatoid arthritis (RA ...
Jiajie Tu, Wenming Hong, Wenming Hong, Pengying Zhang, Xinming Wang, Xinming Wang, Heinrich Körner, Wei Wei   +7 more
doaj   +1 more source

The Role of CTHRC1 in Regulation of Multiple Signaling and Tumor Progression and Metastasis

Mediators of Inflammation, 2020
Collagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. CTHRC1 expresses mainly in adventitial fibroblasts and neointimal smooth muscle cells of balloon-injured vessels and promotes cell migration and tissue ...
Dan Mei, Yue Zhu, Lingling Zhang, Wei Wei   +3 more
doaj   +1 more source

Anti-bacterial, Anti-oxidant and Anti-inflammatory Activity of Leaf Extract of Christella acuminata [PDF]

Natural source being a valuable resource of medicine, Christella acuminata (fern), is considered in the present study, where its ethanolic and aqueous leaf extracts were examined for phytochemical screening, antibacterial activity, antioxidant activity ...
Gayatri Thapa, Ananya Bhattacharjee, Ashsis Sapkota, Shalini Singh, Mahak R Chetri, Prabika Rai   +5 more
core   +1 more source

Lyprinol : is it a useful anti-inflammatory agent? [PDF]

, 2009
The New Zealand green lipped mussel preparation Lyprinol is available without a prescription\ud from a supermarket, pharmacy or Web. The Food and Drug Administration have recently\ud warned Lyprinol USA about their extravagant anti-inflammatory claims ...
Doggrell, Sheila
core   +2 more sources

Ginsenoside Rg1 treatment protects against cognitive dysfunction via inhibiting PLC–CN–NFAT1 signaling in T2DM mice

Journal of Ginseng Research, 2023
Background: As a complication of Type II Diabetes Mellitus (T2DM), the etiology, pathogenesis, and treatment of cognitive dysfunction are still undefined.
Xianan Dong, Liangliang Kong, Lei Huang, Yong Su, Xuewang Li, Liu Yang, Pengmin Ji, Weiping Li, Weizu Li   +8 more
doaj   +1 more source

The application of HER2 and CD47 CAR-macrophage in ovarian cancer

Journal of Translational Medicine, 2023
Background The chimeric antigen receptor (CAR)-T therapy has a limited therapeutic effect on solid tumors owing to the limited CAR-T cell infiltration into solid tumors and the inactivation of CAR-T cells by the immunosuppressive tumor microenvironment ...
Yizhao Chen, Xiangling Zhu, Hanze Liu, Cunzhi Wang, Yu Chen, Huihui Wang, Yilong Fang, Xuming Wu, Yuting Xu, Chunhua Li, Xinyue Lv, Jinghua Huang, Xintong Han, Ruilin Li, Wenming Hong, Zhiying Yu, Wei Wei, Jiajie Tu   +17 more
doaj   +1 more source

Long non-coding RNAs: Potential therapeutic targets for epilepsy

Frontiers in Neuroscience, 2022
Epilepsy is a common and disastrous neurological disorder characterized by abnormal firing of neurons in the brain, affecting about 70 million people worldwide.
Sen Liu, Sen Liu, Sen Liu, Min Fan, Min Fan, Min Fan, Meng-Die Ma, Meng-Die Ma, Meng-Die Ma, Jin-Fang Ge, Jin-Fang Ge, Jin-Fang Ge, Fei-Hu Chen, Fei-Hu Chen, Fei-Hu Chen   +14 more
doaj   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Cyclopentenone prostaglandins as anti-inflammatory agents: a novel therapeutic strategy.

, 2003
Cyclopentenone prostaglandins (cyPG) are naturally occurring derivatives of prostaglandin E1, E2, and D2 containing an α,β-unsaturated carbonyl group in the cyclopentane ring structure (cyclopentenone).
IANARO, ANGELA, MAFFIA P, IALENTI, ARMANDO, DI ROSA M, Rosa, M., Maffia, P., Ianaro, A., Ialenti, A.   +7 more
core   +1 more source