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Immune-Cell-Based Therapy for COVID-19: Current Status
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. The interplay between innate and adaptive immune responses plays a crucial role in managing COVID-19.
Yiyuan Wang +7 more
doaj +1 more source
Anti‐Inflammatory Natural Products [PDF]
Inflammation is the first biological response of the immune system against infection or irritation. However, accumulating epidemiological and clinical study indicates that zealous acute inflammation or chronic inflammatory reaction is a significant risk factor to develop various human diseases.
Yifu Yang +3 more
openaire +3 more sources
Novel antioxidant and anti-inflammatory peptides from the Siamese crocodile (Crocodylus siamensis) hemoglobin hydrolysate [PDF]
Novel antioxidant and anti-inflammatory peptides were isolated from hydrolysates of Siamese crocodile (Crocodylus siamensis) hemoglobin. C. siamensis hemoglobin hydrolysates (CHHs) were obtained by pepsin digestion at different incubation times (2, 4, 6,
Jangpromma, Nisachon +7 more
core +1 more source
Molecular Mechanisms of T Cells Activation by Dendritic Cells in Autoimmune Diseases
The interaction between T cell and dendritic cells (DCs) that leads to T cell activation affects the progression of the immune response including autoimmune diseases. Antigen presentation on immune cell surface, formation of an immunological synapse (IS),
Yu Tai +5 more
doaj +1 more source
Synovial Macrophages in Rheumatoid Arthritis: The Past, Present, and Future
The ontogeny of macrophages in most organs has already been established. Owing to the limited number and inaccessibility of synovial macrophages (SMs), the origin of SMs has not been fully elucidated.
Jiajie Tu +7 more
doaj +1 more source
MicroRNA-10b promotes arthritis development by disrupting CD4+ T cell subtypes
Rheumatoid arthritis (RA) is an inflammation-involved disorder and features the disruption of CD4+ T lymphocytes. Herein, we describe that microRNA-10b-5p (miR-10b) promotes RA progression by disrupting the balance between subsets of CD4+ T cells.
Jiajie Tu +9 more
doaj +1 more source
The glucocorticoid receptor in inflammatory processes : transrepression is not enough [PDF]
Glucocorticoids (GCs) are the most commonly used anti-inflammatory agents to treat inflammatory and immune diseases. However, steroid therapies are accompanied by severe side-effects during long-term treatment. The dogma that transrepression of genes, by
Dejager, Lien +3 more
core +2 more sources
Bidirectional Role of β2-Adrenergic Receptor in Autoimmune Diseases
Disorder of the sympathetic nervous system (SNS) is closely related to the pathogenesis of various autoimmune diseases (ADs). Catecholamine triggered beta2-adrenergic receptor (β2-AR) signaling is important in creating a bidirectional response in the ...
Li Wu +9 more
doaj +1 more source
Metastasis has emerged as a major impediment to achieve successful therapeutic outcomes in hepatocellular carcinoma (HCC). Nonetheless, the intricate molecular mechanisms governing the progression of HCC remain elusive.
Xiu Chen +8 more
doaj +1 more source
Rheumatoid arthritis (RA) is an autoimmune disease and is mainly characterized by abnormal proliferation of fibroblast-like synoviocytes (FLS). The up-regulated cellular membrane expression of G protein coupled receptor kinase 2 (GRK2) of FLS plays a ...
Chenchen Han +12 more
doaj +1 more source

