Results 81 to 90 of about 4,294,591 (308)

Cyclopentenone prostaglandins as anti-inflammatory agents: a novel therapeutic strategy.

, 2003
Cyclopentenone prostaglandins (cyPG) are naturally occurring derivatives of prostaglandin E1, E2, and D2 containing an α,β-unsaturated carbonyl group in the cyclopentane ring structure (cyclopentenone).
IANARO, ANGELA, MAFFIA P, IALENTI, ARMANDO, DI ROSA M, Rosa, M., Maffia, P., Ianaro, A., Ialenti, A.   +7 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Emerging Roles for G-protein Coupled Receptors in Development and Activation of Macrophages

Frontiers in Immunology, 2019
Macrophages have emerged as a key component of the innate immune system that emigrates to peripheral tissues during gestation and in the adult organism.
Xinming Wang, Xinming Wang, Abishek Iyer, A. Bruce Lyons, Heinrich Körner, Heinrich Körner, Wei Wei   +6 more
doaj   +1 more source

Vascular Disease, Non-Steroidal Anti-Inflammatory Drugs and Risk of Parkinson's Disease. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Wotton C, Hermon C, Floud S, Reeves G, Barnes I.   +4 more
europepmc   +2 more sources

Anti-inflammatory diet or anti-inflammatory lifestyle?

Giornale di Clinica Nefrologica e Dialisi
Chronic low-grade inflammation is increasingly proving to be one of the main culprits for the onset of numerous pathologies. Until recently, to try to combat this insidious enemy, we mainly resorted to anti-inflammatory diets, but current scientific evidence seems to support the hypothesis that the maximum impact on health could be obtained above all ...
David Mariani, Sabrina Lucchetti
openaire   +2 more sources

Lyprinol : is it a useful anti-inflammatory agent? [PDF]

, 2009
The New Zealand green lipped mussel preparation Lyprinol is available without a prescription\ud from a supermarket, pharmacy or Web. The Food and Drug Administration have recently\ud warned Lyprinol USA about their extravagant anti-inflammatory claims ...
Doggrell, Sheila
core   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Anti-Inflammatory Effects and Mechanisms of Pudilan Antiphlogistic Oral Liquid

, 2021
Pudilan antiphlogistic oral liquid (PDL) is a commercial traditional Chinese medicine widely used in the treatment of a variety of inflammatory diseases.
Xiaoqun Gu (11817112), Yifan Xu (87249), Kaifan Bao (6017810), Gang Tian, Gang Tian (112190), Min Hong, Xiaoqun Gu, Jie Zheng, Xuerui Yu, Yifan Xu, Xuerui Yu (8382960), Min Hong (279203), Yuheng Zhang (1543663), Kaifan Bao, Jie Zheng (31208), Yuheng Zhang   +15 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source