Results 91 to 100 of about 2,980,164 (354)

High‐density lipoprotein in diabetes: Structural and functional relevance

Journal of Diabetes Investigation
Low levels of high‐density lipoprotein‐cholesterol (HDL‐C) is considered a major cardiovascular risk factor. However, recent studies have suggested a more U‐shaped association between HDL‐C and cardiovascular disease.
David Tak Wai Lui, Kathryn Choon Beng Tan   +1 more
doaj   +1 more source

Anti-inflammatory and Anti-arthritic Potentials of Maesa Montana Roots

Walailak Journal of Science and Technology, 2021
Maesa Montana is a flowering plant of the Myrsinaceae family, which is locally known as ramjani. The current study aimed to evaluate the in-vitro anti-arthritic and anti-inflammatory activities of the root extract of this plant.
Sanjida SHARMIN, Rabeya Gazi JHUMA, Sanjida ISLAM, Riniara KHATUN   +3 more
doaj   +1 more source

Protective effects of urocortin 2 against caerulein-induced acute pancreatitis. [PDF]

, 2019
Because little is known about the role of corticotropin-releasing factor (CRF) agonists in regulating responses in pancreatitis, we evaluated the effects of urocortin 2 (UCN2) and stressin1 in caerulein-induced acute pancreatitis (AP) model in rats. Male
Bhargava, Aditi, Chheda, Chintan, Hasdemir, Burcu, Pandol, Stephen J, Rivier, Jean, Tan, Tanya, Yuan, Jingzhen   +6 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Synthesis and Anti-Inflammatory Activity of Pyrazolines

E-Journal of Chemistry, 2010
Some new pyrazoline derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with phenyl hydrazine hydrochloride in the presence of alcohol.
B. Ramesh, T. Sumana
doaj   +1 more source

Anti-Inflammatory activity of a polyphenolic extract from Arabidopsis thaliana in in vitro and in vivo models of Alzheimer's Disease [PDF]

, 2019
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the primary form of dementia in the elderly. One of the main features of AD is the increase in amyloid-beta (Aβ) peptide production and aggregation, leading to oxidative stress ...
Casale, Assunta Maria, Costantino, Paolo, D'Erme, Maria, Francioso, Antonio, Gazzino, Roberta, Mancini, Patrizia, Mattioli, Roberto, Mosca, Luciana, Piacentini, Lucia, Trovato, Maurizio, Wessjohann, Ludger   +10 more
core   +1 more source

Anti‐inflammatory activity of cationic lipids [PDF]

British Journal of Pharmacology, 1997
The effect of liposome phospholipid composition has been assumed to be relatively unimportant because of the presumed inert nature of phospholipids. We have previously shown that cationic liposome formulations used for gene therapy inhibit, through their cationic component, the synthesis by activated macrophages of the pro‐inflammatory mediators ...
M C, Filion, N C, Phillips
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Phytochemical Profiling Using GCMS and HPLC and Evaluation of Anti-oxidant, Anti-inflammatory and Anti-bacterial Activities of Lawsonia Inermis

Pakistan Journal of Analytical & Environmental Chemistry
Lawsonia inermis leaves are often used in traditional medicine for the treatment of various disorders. The main objectives of this study were to assess the phytochemical composition of the plant using various analytical techniques and also to investigate
Ahdania Batool , Jamshaid Akbar , Kanwal Ashiq, Abubakar Munir, Khaled Alsubari, Sana Ashiq   +5 more
doaj   +1 more source

Evaluation of the in vivo anti-inflammatory activity of a flavone glycoside from Cancrinia discoidea (Ledeb.) Poljak [PDF]

, 2011
The anti-inflammatory effect of selagin-7-O-(6″-O-Acetyl-)-β-D-glucoside, isolated from the medicinal herb Cancrinia discoidea (Ledeb.) Poljak, was evaluated for its anti-inflammatory activity in the carrageenin- and serotonin-induced rat paw oedema ...
Li, Qing-Chan, Su, Jian-Yu, Zhu, Liang
core