Results 71 to 80 of about 1,759,549 (313)

Phytochemical Analysis, Anti-Inflammatory, and Antioxidant Activity of Selected Medicinal Plants in Mandiangin Rainforest in South Kalimantan, Indonesia

Journal of Tropical Life Science, 2023
Mandiangin is one of the tropical rainforests in South Kalimantan, with highly diverse plants used for health and medicinal purposes. To date, scientific evidence on these plants' content and bioactivities remain lacking for further medical applications.
Yusanto Nugroho, Windy Budianto, Salmon Siahaan, Purwakaning Agung, Iskandar Thalib, Eko Suhartono   +5 more
doaj   +1 more source

Antinociceptive, anti-inflammatory, and antipyretic properties of an aqueous extract of Dicranopteris linearis leaves in experimental animal models [PDF]

, 2008
This study was performed out to establish the antinociceptive, anti-inflammatory, and antipyretic properties of an aqueous extract of Dicranopteris linearis leaves in experimental animals.
Abdul Ghani, Zuleen Delina Fasya, Abdul Kadir, Arifah, Gopalan, Hanan Kumar, Mat Jais, Abdul Manan, Raden Mohd Nor, Raden Nur Suraya, Ripin, Johari, Somchit, Muhammad Nazrul, Sulaiman, Mohd Roslan, Zakaria, Zainul Amiruddin   +8 more
core   +1 more source

Exploring the anti‐inflammatory activity of sulforaphane

Immunology & Cell Biology, 2023
AbstractDysregulation of innate immune responses can result in chronic inflammatory conditions. Glucocorticoids, the current frontline therapy, are effective immunosuppressive drugs but come with a trade‐off of cumulative and serious side effects. Therefore, alternative drug options with improved safety profiles are urgently needed.
Katie Treasure, James Harris, Gary Williamson   +2 more
openaire   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

High‐density lipoprotein in diabetes: Structural and functional relevance

Journal of Diabetes Investigation
Low levels of high‐density lipoprotein‐cholesterol (HDL‐C) is considered a major cardiovascular risk factor. However, recent studies have suggested a more U‐shaped association between HDL‐C and cardiovascular disease.
David Tak Wai Lui, Kathryn Choon Beng Tan   +1 more
doaj   +1 more source

Unlocking the in vitroanti- inflammatory and antidiabetic potential of Polygonum maritimum [PDF]

, 2017
Context: Several Polygonum species (Polygonaceae) are used in traditional medicine in Asia, Europe and Africa to treat inflammation and diabetes. Objective: Evaluate the in vitro antioxidant, anti-inflammatory and antidiabetic potential of methanol and ...
Alice Martins, Amélia P. Rauter, Andreia Lopes, Bhandari U, Huang X, José M. F. Nogueira, João Varela, Kilinc M, Luísa Barreira, Luísa Custódio, Maria João Rodrigues, Marta Oliveira, Muriach M, Nishishiro M, Nuno R. Neng, Shai LJ, Veerasamy R   +16 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Anti‐inflammatory activity of cationic lipids [PDF]

British Journal of Pharmacology, 1997
The effect of liposome phospholipid composition has been assumed to be relatively unimportant because of the presumed inert nature of phospholipids. We have previously shown that cationic liposome formulations used for gene therapy inhibit, through their cationic component, the synthesis by activated macrophages of the pro‐inflammatory mediators ...
M C, Filion, N C, Phillips
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Phytochemical Profiling Using GCMS and HPLC and Evaluation of Anti-oxidant, Anti-inflammatory and Anti-bacterial Activities of Lawsonia Inermis

Pakistan Journal of Analytical & Environmental Chemistry
Lawsonia inermis leaves are often used in traditional medicine for the treatment of various disorders. The main objectives of this study were to assess the phytochemical composition of the plant using various analytical techniques and also to investigate
Ahdania Batool , Jamshaid Akbar , Kanwal Ashiq, Abubakar Munir, Khaled Alsubari, Sana Ashiq   +5 more
doaj   +1 more source