Results 61 to 70 of about 1,759,549 (313)

Immunomodulatory effects of 17-O-acetylacuminolide in RAW264.7 cells and HUVECs : involvement of MAPK and NF-κB pathways [PDF]

open access: yes, 2014
The terpenoid 17-O-acetylacuminolide (AA) was shown to inhibit the production of several inflammatory mediators. However, the mechanisms by which this compound elicited its anti-inflammatory activity remain to be elucidated.
Achoui, Mouna   +5 more
core   +1 more source

Post-ischaemic immunological response in the brain: targeting microglia in ischaemic stroke therapy [PDF]

open access: yes, 2020
Microglia, the major endogenous immune cells of the central nervous system, mediate critical degenerative and regenerative responses in ischaemic stroke.
Chen, Ruoli   +4 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Novel N-phenylcarbamothioylbenzamides with anti-inflammatory activity and prostaglandin E2 inhibitory properties

open access: yesDrug Design, Development and Therapy, 2013
Carmen Limban,1 Alexandru Vasile Missir,1 Khairi Mustafa Salem Fahelelbom,2 Moawia Mohammad Al-Tabakha,2 Miron Teodor Caproiu,3 Bassem Sadek4 1Department of Pharmaceutical Chemistry, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania ...
Limban C   +5 more
doaj  

Anti-inflammatory activity of the methanolic extracts of leaves and stems from Tabebuia hypoleuca (C. Wright) Urb. [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2015
Context: There are reports in the literature of species belonging to the genus Tabebuia with pharmacological potential as anti-inflammatory: Tabebuia avellanedae, Tabebuia chrysanta, Tabebuia rosea, Tabebuia ochracea, among others; however, about of the ...
Ada I. Regalado   +2 more
doaj  

EFFECT OF DIFFERENT DOSES OF PUMPKIN SEED OIL AS AN ANTI-INFLAMMATORY AND ANALGESIC ON MICE

open access: yesThe Iraqi Journal of Agricultural science, 2020
To evaluate the role of anti-inflammatory and analgesicof Iraqi pumpkin seed oil. The oil seed (25-100 mg / kg) were investigated using various experimental models for analgesic and anti-inflammatory benefit.
N. Z. yahya
doaj   +1 more source

Research Progress on Anti-inflammatory Activity Mechanism and Structure-activity Relationship of Plant Polysaccharides

open access: yesShipin gongye ke-ji, 2022
Plant polysaccharides, one of the main sources of polysaccharides, has many important pharmacological functions. This paper reviews the research progress of anti-inflammatory activity of plant polysaccharides in recent years, focusing on the anti ...
Chuang LIU   +3 more
doaj   +1 more source

Antimicrobial and anti-inflammatory activity of chitosan-alginate nanoparticles: a targeted therapy for cutaneous pathogens. [PDF]

open access: yes, 2013
Advances in nanotechnology have demonstrated potential application of nanoparticles (NPs) for effective and targeted drug delivery. Here we investigated the antimicrobial and immunological properties and the feasibility of using NPs to deliver ...
Blecher-Paz, Karin   +10 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Synthesis and Anti-Inflammatory Activity of Pyrazolines

open access: yesE-Journal of Chemistry, 2010
Some new pyrazoline derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with phenyl hydrazine hydrochloride in the presence of alcohol.
B. Ramesh, T. Sumana
doaj   +1 more source

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