Results 251 to 260 of about 2,980,164 (354)

Development of a submicron emulsion-based delivery system to improve the anti-inflammatory activity of urolithin A. [PDF]

J Pharm Pharm Sci
Esposito E, Dzyhovskyi V, Santamaria F, Marvelli L, Boldrini P, Mariani P, Pepe A, Ortore MG, Benedusi M, Valacchi G, Ferraro L.   +10 more
europepmc   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

The TRPV1 Channel Modulator Imidazo[1,2-a]Indole Derivative Exhibits Pronounced and Versatile Anti-Inflammatory Activity In Vivo. [PDF]

Biomedicines
Galenko-Yaroshevsky PA, Zelenskaya AV, Suzdalev KF, Popova TN, Kvetkina AN, Shamatova MM, Chuyan EN, Ravaeva MY, Murashko RA, Glechyan TR, Sergeeva AV, Ishkhanyan NN, Gulevskaya ON, Chubinskiy-Nadezhdin VI, Kryl'skii ED, Priymenko NA, Klimovich AA, Leychenko EV, Kozlov SA.   +18 more
europepmc   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Anti-Inflammatory Activity-Guided Isolation and In Silico Validation of Turmeric (<i>Curcuma longa</i> L.) Phytochemicals. [PDF]

Foods
Uvaniskanova Z, Hafez-Ghoran S, Ikhlas Abdjan M, Mountessou BYG, Taktaz F, Mulya F, Seitimova GA, Iqbal Choudhary M.   +7 more
europepmc   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Whole-Grain <i>Oryza sativa</i> L. Flour Extract Exhibits Potent Antioxidant and Anti-Inflammatory Activity in Rats with Experimentally Induced Inflammation. [PDF]

Molecules
Ferențiu I, Pop TI, Pârvu AE, Orăsan MS, Bolunduț D, Pârvu M, Ranga F, Dalai CO, Țicolea M, But AE, Usatiuc LO, Pop RM.   +11 more
europepmc   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

Structural Properties and Anti-Inflammatory Activity of GLP-P, a Kefir-Derived Neutral Glycopeptide. [PDF]

Foods
Yang Y, Zhang Z, Bai Y.
europepmc   +1 more source