Results 81 to 90 of about 96,395 (289)

Dosage Effects of Histamine-2 Receptor Antagonist on the Primary Prophylaxis of Non-Steroidal Anti-Inflammatory Drug (NSAID)-Associated Peptic Ulcers: A Retrospective Cohort Study [PDF]

, 2014
postprin
Chan, EW, He, Y, Ho, LM, Lau, CY, Leung, WK, Man, KCK, Wong, ICK   +6 more
core   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Xanthones, A Promising Anti-Inflammatory Scaffold: Structure, Activity, and Drug Likeness Analysis

Molecules, 2020
Inflammation is the body’s self-protective response to multiple stimulus, from external harmful substances to internal danger signals released after trauma or cell dysfunction.
Zheling Feng, Xiuqiang Lu, Lishe Gan, Qingwen Zhang, Ligen Lin   +4 more
doaj   +1 more source

Analysis of gut microbiota in rheumatoid arthritis patients. Disease-related dysbiosis and modifications induced by etanercept [PDF]

, 2018
A certain number of studies were carried out to address the question of how dysbiosis could affect the onset and development of rheumatoid arthritis (RA), but little is known about the reciprocal influence between microbiota composition and ...
D'Amelio, R, Di Rosa, R, Laganà, B, Panebianco, C, Pazienza, V, Picchianti-Diamanti, A, Salemi, S, Salerno, G, Sgrulletti, Mayla, Sorgi, Ml, Terracciano, F, Tropea, A   +11 more
core   +1 more source

A Polyoxometalate—Carbon Nanotube Enhanced Electrochemical Sensor for Aptamer‐Based Diagnostics

Advanced Sensor Research, EarlyView.
The high electroactive surface area of multi‐walled carbon nanotubes decorated with aptamer‐functionalized polyoxovanadate units enables a ≈1000‐fold increase in peak current response for a model diclofenac detection in aqueous solution compared to unmodified platinum microelectrodes.
Eric Vogelsberg, Andriy Lotnyk, Kirill Monakhov   +2 more
wiley   +1 more source

Disparities in rate, triggers, and management in pediatric and adult cases of suspected drug‐induced anaphylaxis in Canada

Immunity, Inflammation and Disease, 2018
Introduction Data is sparse on drug‐induced anaphylaxis (DIA) and there have not been studies assessing the differences in clinical characteristics and management of DIA between adults and children.
Sofianne Gabrielli, Ann E. Clarke, Harley Eisman, Judy Morris, Lawrence Joseph, Sebastien La Vieille, Peter Small, Rodrick Lim, Paul Enarson, Michal Zelcer, Edmond S. Chan, Chris Mill, Moshe Ben‐Shoshan   +12 more
doaj   +1 more source

Evaluation of the usefulness of a computer‐based learning program to support student learning in pharmacology [PDF]

, 1999
This study aims to evaluate the effectiveness of a computer‐based teaching program in supporting and enhancing traditional teaching methods. The program covers the pharmacology of inflammation and has been evaluated with a group of second‐year medical ...
Brain, S., Dewhurst, D. G., Williams, A. D.   +2 more
core   +2 more sources

Possibilities of Inner Ear Barrier Models for Otologic Drug Development

Advanced Therapeutics, EarlyView.
This review examines innovative organ chip models that reconstruct critical inner ear barriers, addressing a fundamental challenge in otologic drug development: the limited understanding of pharmaceutical behavior across these complex barriers. By replicating these barriers, the advanced models offer promising alternatives to traditional testing ...
Yeji Ahn, Seonmin Choi, Minju Kim, Zachary Estlack, Daniel Brown, Jaehong Key, Young Joon Seo, Jungkyu Kim   +7 more
wiley   +1 more source

Salivary gland derived peptides as a new class of anti-inflammatory agents: review of preclinical pharmacology of C-terminal peptides of SMR1 protein

Journal of Inflammation, 2010
The limitations of steroidal and non steroidal anti-inflammatory drugs have prompted investigation into other biologically based therapeutics, and identification of immune selective anti-inflammatory agents of salivary origin.
Befus A Dean, Davison Joseph S, Mathison Ronald D, Gingerich Daniel A   +3 more
doaj   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source